A5100402340- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Sinusitis and nasal conditions
- Antioxidant Activity and Oxidative Stress
- Gastric Cancer Management and Outcomes
- Retinoids in leukemia and cellular processes
- Pancreatic and Hepatic Oncology Research
- Head and Neck Surgical Oncology
- Gallbladder and Bile Duct Disorders
- Dermatology and Skin Diseases
- Nasal Surgery and Airway Studies
- Pancreatitis Pathology and Treatment
- Infectious Diseases and Mycology
- Pediatric health and respiratory diseases
- Metastasis and carcinoma case studies
- Liver Disease Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Esophageal and GI Pathology
- Neonatal Respiratory Health Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Liver Disease and Transplantation
- Gastrointestinal disorders and treatments
- Tracheal and airway disorders
Beijing Institute of Neurosurgery
2015-2025
Beijing Tongren Hospital
2016-2025
Capital Medical University
2016-2025
Fudan University
2009-2025
Henan Provincial People's Hospital
2020-2025
Hohai University
2025
China Mobile (China)
2025
Institute of Computing Technology
2021-2025
Chinese Academy of Sciences
2021-2025
Jean Mayer Human Nutrition Research Center on Aging
2010-2024
To date, no study has evaluated the diversity of TH cell cytokine patterns patients with chronic rhinosinusitis (CRS) among centers in different continents using identical methods.We sought to assess profiles CRS from Europe, Asia, and Australia.Patients nasal polyps (CRSwNP) without (CRSsNP; n = 435) control subjects (n 138) were recruited Adelaide, Benelux, Berlin, Beijing, Chengdu, Tochigi. Nasal mucosal concentrations TH2, TH17, TH1 cytokines; eosinophilic cationic protein (ECP);...
The first officially documented management of the mentally ill in China was Tang Dynasty (618–907 AD), when homeless widows, orphans and were cared for Bei Tian Fang, a type charity facility administrated by monks 1. western style psychiatric hospital established funded 1898 an American missionary, John Kerr, what is currently Guangzhou Brain Hospital. In next 50 years, hospitals built very slowly limited number large cities. psychiatrists gradually increased to 100, beds amounted 1,000....
Inflammatory diseases are often chronic and recurrent, current treatments do not typically remove underlying disease drivers1. T cells participate in a wide range of inflammatory such as psoriasis2, Crohn's disease3, oesophagitis4 multiple sclerosis5,6, clonally expanded antigen-specific may contribute to chronicity recurrence, part by forming persistent pathogenic memory. Chronic rhinosinusitis asthma airway that present comorbidities7. affects more than 10% the general population8. Among...
Previous studies have shown that beta-carotene 15,15'-monooxygenase catalyzes the cleavage of at central carbon 15,15'-double bond but cleaves lycopene with much lower activity. However, expressing mouse carotene 9',10'-monooxygenase (CMO2) in beta-carotene/lycopene-synthesizing and -accumulating Escherichia coli strains leads to both a color shift formation apo-10'-carotenoids, suggesting oxidative carotenoids their 9',10'-double bond. Here we provide information on biochemical...
Abstract Epidemiological and experimental studies provide supportive evidence that lycopene (LY), a major carotenoid from tomatoes tomato products, may act as chemopreventive agent against certain types of cancers. We recently showed high‐fat diet (HFD)‐induced nonalcoholic steatohepatitis (NASH) promoted diethylnitrosamine (DEN)‐initiated hepatocarcinogenesis in rat model. Using this model, we investigated the efficacy an equivalent dosage dietary LY either pure compound or extract (TE)...
There is little evidence on the efficacy of glucocorticoid transnasal nebulization therapy in patients with eosinophilic chronic rhinosinusitis nasal polyps (CRSwNP).We sought to evaluate immunologic and remodeling effects budesonide CRSwNP.Sixty CRSwNP were randomized receive or placebo treatment for 14 days by means a double-blind manner. Endoscopic polyp size scores (maximum = 6 points, Kennedy score) visual analog scale symptoms assessed before after treatment. Similarly, samples...
Abstract The second largest Phanerozoic mass extinction occurred at the Ordovician-Silurian (O-S) boundary. However, unlike other major events, driver for O-S remains uncertain. abundance of mercury (Hg) and total organic carbon (TOC) Ordovician early Silurian marine sediments were analyzed from four sections (Huanghuachang, Chenjiahe, Wangjiawan Dingjiapo) in Yichang area, South China, as a test evidence massive volcanism associated with event. Our results indicate Hg concentrations...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal pathogen of ongoing global pandemic disease 2019 (COVID-19). Loss smell and taste are symptoms COVID-19, may be related to cilia dysfunction. Here, we found that SARS-CoV-2 ORF10 increases overall E3 ligase activity CUL2ZYG11B complex by interacting with ZYG11B. Enhanced causes increased ubiquitination subsequent proteasome-mediated degradation an intraflagellar transport (IFT) B protein, IFT46, thereby impairing both...
Abstarct Odontogenic maxillary sinusitis (OMS) is a subtype of (MS). It actually inflammation the sinus that secondary to adjacent infectious dental lesion. Due lack unique clinical features, OMS difficult distinguish from other types rhinosinusitis. Besides, characteristic pathogeny makes it resistant conventional therapies Its current diagnosis and treatment are thus facing great difficulties. The multi-disciplinary cooperation between otolaryngologists dentists absolutely urgent settle...
Thymic stromal lymphopoietin (TSLP) played an important role in the pathogenesis of allergic rhinitis (AR) and can be regarded a potential therapeutic target for management AR.To evaluate possible TSLP AR.We enrolled 16 patients AR to investigate expression nasal mucosa link interleukin-4 (IL-4). Expression was detected by immunohistochemical analysis quantitative reverse transcriptase-polymerase chain reaction (RT-PCR), concentrations IL-4 were measured enzyme-linked immunosorbent assay...
Immature corn grains are becoming increasingly popular as a snack/vegetable, facilitating human consumption in some countries. Of particular interest were their nutritional and functional properties. Therefore, plants at stages M1 (74 DAS), M2 (86 M3 (98 maturity stage (116 where DAS refers to days after seeding, investigated for changes of the nutrients, phytochemicals, antioxidant activity during maturation. Results revealed that maturation grains, content reducing sugar crude protein...