A5073539318- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Sinusitis and nasal conditions
- Respiratory and Cough-Related Research
- Nasal Surgery and Airway Studies
- Olfactory and Sensory Function Studies
- Food Allergy and Anaphylaxis Research
- Drug-Induced Adverse Reactions
- Dermatology and Skin Diseases
- Tracheal and airway disorders
- Myasthenia Gravis and Thymoma
- Obstructive Sleep Apnea Research
- Inflammatory mediators and NSAID effects
- Ear Surgery and Otitis Media
- Urticaria and Related Conditions
- Airway Management and Intubation Techniques
- Peripheral Neuropathies and Disorders
- Otitis Media and Relapsing Polychondritis
- Ocular Surface and Contact Lens
- IL-33, ST2, and ILC Pathways
- Pediatric health and respiratory diseases
- Inflammasome and immune disorders
- Monoclonal and Polyclonal Antibodies Research
- Head and Neck Surgical Oncology
- Cystic Fibrosis Research Advances
University College London
2016-2025
Institute of Infection and Immunity
2023-2025
Royal Brompton Hospital
2023-2024
University of Ulster
2003-2024
Royal Victoria Hospital
2003-2024
Royal National Throat Nose and Ear Hospital
2013-2023
University College Hospital
2018-2023
University College London Hospitals NHS Foundation Trust
2017-2022
Royal London Hospital
2015-2022
Faculty (United Kingdom)
2021
Summary This guidance for the management of patients with allergic and non‐allergic rhinitis has been prepared by Standards Care Committee (SOCC) British Society Allergy Clinical Immunology (BSACI). The guideline is based on evidence as well expert opinion use both adult physicians paediatricians practicing in allergy. recommendations are graded. During development these guidelines, all BSACI members were included consultation process using a web‐based system. Their comments suggestions...
NSAID-exacerbated respiratory disease (N-ERD) is a chronic eosinophilic, inflammatory disorder of the tract occurring in patients with asthma and/or rhinosinusitis nasal polyps (CRSwNP), symptoms which are exacerbated by NSAIDs, including aspirin. Despite some progress understanding pathophysiology syndrome, affects 1/10 and rhinosinusitis, it remains diagnostic therapeutic challenge. In order to provide evidence-based recommendations for diagnosis management N-ERD, panel international...
Nasal endoscopy is not only used for the diagnosis of chronic rhinosinusitis with nasal polyps (CRSwNP), but also monitoring response to therapy playing an important role in both daily practice and research. In contrast patient-reported outcomes, endoscopic polyp scoring by independent blinded readers objective measurement, influenced placebo effect. It safer cheaper compared computed tomography imaging therefore, better suited regular assessments extent disease. Since early 90s, a variety...
Severe chronic rhinosinusitis with nasal polyps (CRSwNP), a form of diffuse bilateral (usually type 2) CRS, is debilitating disease significant impact on quality life (QoL). With novel knowledge and treatment options becoming available, there growing need to update or revise key definitions enable communication across different specialties dealing agree goals care in CRSwNP. The European Forum for Research Education Allergy Airway diseases (EUFOREA) EPOS expert members discussed how measure...
Patients with asthma who have aspirin sensitivity greater cysteinyl leukotriene production and airway hyperresponsiveness to the effects of inhaled leukotrienes than their aspirin-tolerant counterparts. We hypothesized that latter effect reflects elevated expression receptor CysLT1 on inflammatory cells in target organ its is down-regulated by desensitization.
Abstract Objectives: To conduct the first prospective, randomized, controlled trial evaluating and comparing medical surgical treatment of polypoid nonpolypoid chronic rhinosinusitis (CRS). Materials Methods: Ninety patients with CRS were equally randomized either to or therapy. All underwent pre‐ posttreatment assessments visual analogue score (VAS), Sinonasal Outcome Test‐20 (SNOT‐20), Short Form 36 Health Survey (SF‐36), nitric oxide (NO), acoustic rhinometry, saccharine clearance time...
Summary In a double‐blind placebo‐controlled cross‐over trial, low dose sublingual therapy with house dust mite was effective in relieving symptoms 72% of the group patients perennial rhinitis due to ( P < 0·03). Following active treatment, there significant increase morning peak nasal inspiratory flow rate 0·01) those who improved (thirteen out eighteen) and resistance provocation also increased, some cases up 1000‐fold 0·05). Oral is safe avoids side effects desensitizing injections...
This article was originally published online on 19 November 2009 Asia Pacific Association of Allergology and Clinical Immunology. Commonwealth Independent States (CIS). European Academy Allergy Immunology (EAACI). Latin American Society Interasma (International Asthmology). Albanian South Africa. Allergy, Asthma College Argentine Australasian Allergy. Bangladesh Belgian Brazilian Immunopathology. British for Bulgarian National Allergology. China Chinese Allergists. Cuban Czech Finnish French...
Summary This guidance for the management of patients with rhinosinusitis and nasal polyposis has been prepared by Standards Care Committee (SOCC) British Society Allergy Clinical Immunology (BSACI). The recommendations are based on evidence expert opinion graded. These guidelines benefit both adult physicians paediatricians treating allergic conditions. Rhinosinusitis implies inflammation nose sinuses which may or not have an infective component includes polyposis. Acute lasts up to 12 weeks...
Abstract This EAACI Task Force document aims at providing the readers with a comprehensive and complete overview of currently available tools for diagnosis nasal sino‐nasal disease. We have tried to logically order different important issues related history taking, clinical examination additional investigative evaluation severity sinonasal disease into consensus document. A panel European experts in field Rhinology has contributed this on Diagnostic Tools Rhinology.
Antiacetylcholine receptor antibody (anti-AChR) was spontaneously synthesized by cultured thymic tissue from 19 of 35 patients with myasthenia gravis. Two other thymus cultures produced after stimulation pokeweed mitogen. Antibody production correlated histologic evidence thymitis, long duration symptoms, or high serum anti-AChR values. None seven thymomas in culture, but suggested that there had been vivo synthesis trapping anti-AChR. Clinical improvement thymectomy, during the short period...