A5067895480- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Mobile Health and mHealth Applications
- Inhalation and Respiratory Drug Delivery
- Pediatric health and respiratory diseases
- Breast Cancer Treatment Studies
- School Health and Nursing Education
- Health Literacy and Information Accessibility
- Medication Adherence and Compliance
- Breast Implant and Reconstruction
- Pharmaceutical studies and practices
- Cancer survivorship and care
- Public Health and Nutrition
- Cystic Fibrosis Research Advances
- Heart Rate Variability and Autonomic Control
- Landslides and related hazards
- Diabetic Foot Ulcer Assessment and Management
- Tunneling and Rock Mechanics
- Neurological and metabolic disorders
- Respiratory Support and Mechanisms
- Delphi Technique in Research
- Peripheral Artery Disease Management
- Chronic Disease Management Strategies
- Global Cancer Incidence and Screening
Memorial University of Newfoundland
2016-2023
Health Sciences Centre
2018-2023
Park Nicollet Clinic
2001
Methodist Hospital
1998
Methodist Hospital Foundation
1998
BACKGROUND Because breast-conserving surgery (BCS), mastectomy alone, and with reconstruction are equally effective for the treatment of early stage breast carcinoma, women's choice among them often focuses on quality-of-life (QOL) issues. Information regarding QOL after these surgical treatments could help women this decision. METHODS Participants in prospective study were women, age 30–85 years, newly diagnosed carcinoma who underwent BCS (n = 103), alone 55), or 40). Quality life was...
Using a mobile health (mHealth) intervention, consisting of smartphone and compatible medical device, has the potential to enhance chronic obstructive pulmonary disease (COPD) treatment outcomes while mitigating care costs.The aim this study was explore facilitators barriers among providers (HCPs) regarding use mHealth interventions for COPD management.This qualitative study. Semistructured individual interviews were conducted with HCPs, including nurses, pharmacists, physicians who work...
Background Using a mobile health (mHealth) intervention consisting of smartphone and compatible medical device has the potential to enhance chronic obstructive pulmonary disease (COPD) treatment outcomes while mitigating care costs. Objective This study aims describe demographics, use, access smartphones patients with COPD. It also explore develop an understanding facilitators barriers that might influence using mHealth interventions for COPD management. Methods was explanatory, sequential...
Despite ample evidence underpinning the efficacy of β2-agonists in asthma and chronic obstructive pulmonary disease (COPD), occurrence β1- β2-adrenoceptors heart suggests that may have deleterious cardiac effects. We investigated association between new users long-or short-acting (LABA or SABA) ICS (inhaled corticosteroids)/LABA major adverse cardiovascular events (MACE).A nested case-control analysis was conducted using UK Clinical Practice Research Datalink patients with asthma, COPD...
Patients with chronic obstructive pulmonary disease (COPD) are often nonadherent medications and have poor inhaler technique. Community pharmacists can help to improve health-related quality of life overall outcomes in patients COPD. We aim measure the effectiveness a systematic, pharmacist-driven intervention on diagnosed COPD.This pragmatic, parallel-group, cluster randomized controlled trial is designed determine multifactorial, pharmacist-led medication adherence, technique, life, health...
Background: The use of mobile health (mHealth) interventions has the potential to enhance chronic obstructive pulmonary disease (COPD) treatment outcomes. Further research is needed determine which mHealth features are required potentially COPD self-management. Aim: aim this study was explore an intervention for management with healthcare providers (HCPs) and patients COPD. It could inform development successful implementation management. Methods: This a qualitative study. We conducted...
Background and Objective . Aboriginal peoples are at a higher risk of many chronic respiratory diseases compared to the general Canadian population. Patients with asthma-COPD overlap (ACO), disease newly described in 2015, associated frequent exacerbations, rapid decline lung function, poor quality life, high mortality, disproportionate utilization health-care resources than patients asthma COPD alone. The objective was investigate prevalence factors ACO peoples. Methods Data from 2012...
Background . Asthma and obesity are two common health problems in the pediatric population. Obesity is associated with several comorbidities which of great consequence. Excess adipose tissue has been linked to asthma a number studies. However, little known about childhood body mass index (BMI) trajectories development phenotypes. Objective The current study aims investigate significance BMI over risk Methods prospective cohort children aged 0-2 years who were followed every for eight through...
Purpose: Gender differences in the incidence, susceptibility and severity of many obstructive airway diseases (OADs) have been well recognized. However, gender inhaled pharmacotherapy profile are not characterized. Methods: We conducted a retrospective cohort study to investigate new-users corticosteroids (ICS), short-or long-acting beta 2 -agonist (SABA or LABA), ICS/LABA, muscarinic antagonist (SAMA LAMA) among patients with asthma, COPD asthma-COPD overlap (ACO). used Clinical Practice...
A retrospective review was conducted of all early-stage breast cancer patients treated with breast-conservation surgery plus radiation therapy (BCS/RT) to determine mortality and recurrence rates evaluate prognostic factors for these outcomes. Between 1982 1988, 121 stages I II were BCS/RT at our institution. Most the (83%) had re-excision initial biopsy site final surgical evaluation, only 4 positive margins (3.2%). Median follow-up 89.7 months. Cox proportional hazards regression models...
Background Asthma is a prevalent disease that affects many Canadians. Persistent asthma can affect quality of life, and has multiple health implications. Maternal age at birth been associated with adverse outcomes in children. Conflicting study results exist regarding maternal childhood asthma. The association between persistent children still unknown.Objective To investigate the relationship ten years age.Methods This prospective cohort including all aged 0-2 who took part first cycle...
Objective: Sex differences in incidence, susceptibility and severity of many chronic respiratory diseases have been long recognized. Asthma-COPD Overlap (ACO) is newly recognized disease with its management guidelines reported 2015. The objective this analysis to identify the female-specific risk factors associated ACO Aboriginal people.Methods: Peoples Survey 2012 (N = 28,410) fourth cycle a national cross-sectional survey representative First Nations living off reserve, Metis Inuit. APS...
The etiology of sex differences in the risk asthma-COPD phenotype and COPD is still not completely understood. Genetic environmental factors are commonly believed to play an important role. This study aims identify sex-specific genetic markers associated with using Canadian Longitudinal Study on Aging (CLSA) Baseline Comprehensive Genomic data. There were a total 1,415 cases. Out them, 504 cases identified. 20,524 participants without diagnosis asthma served as controls. We performed...
BACKGROUND Because breast-conserving surgery (BCS), mastectomy alone, and with reconstruction are equally effective for the treatment of early stage breast carcinoma, women's choice among them often focuses on quality-of-life (QOL) issues. Information regarding QOL after these surgical treatments could help women this decision. METHODS Participants in prospective study were women, age 30–85 years, newly diagnosed carcinoma who underwent BCS (n = 103), alone 55), or 40). Quality life was...
Asthma patients may have an increased risk for diagnosis of chronic obstructive pulmonary disease (COPD). However, factors accelerating time-to-COPD are unclear. This study aims to estimate associated with the incidence COPD in asthma patients. Canada's Population Data BC (PopData BC) was used identify without prior between January 1, 1998, December 31, 1999. Patients were assessed time-to-incidence from 2000, 2018. The estimated effects several predicting during 18-year follow-up period....
Background: Poor adherence to prescribed asthma medications and risk of severe exacerbations have been well established. However, the effects changes in medication compliance levels subsequent COPD is unknown yet be investigated. This study investigated independent effect (MA) severity on COPD. Methods: We used four linked administrative health databases from Population data BC identify patients aged 18 years older between January 1, 1998 December 31, 1999 without diagnosis The primary event...
This study investigated the association between varying cutoffs for Medication Adherence (MA) among physician-diagnosed asthma patients and subsequent with exacerbation.We linked four administrative health databases obtained from Population Data in British Columbia. Index cases were January 1, 1998, to December 31, 1999, aged 18 years older. Patients prospectively assessed follow-up period 2000, 2018, identify exacerbation. Two proxy measures used assess MA: proportion of days covered (PDC)...