A5026197982- Lung Cancer Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Treatments and Mutations
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tracheal and airway disorders
- Endoplasmic Reticulum Stress and Disease
- Pulmonary Hypertension Research and Treatments
- Medical Imaging and Pathology Studies
- Ultrasound and Hyperthermia Applications
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Neuroscience of respiration and sleep
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Ultrasound in Clinical Applications
- Intraoperative Neuromonitoring and Anesthetic Effects
- Intracranial Aneurysms: Treatment and Complications
- Obstructive Sleep Apnea Research
- Nonmelanoma Skin Cancer Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Respiratory Support and Mechanisms
- Research on Leishmaniasis Studies
- Cutaneous Melanoma Detection and Management
- Cardiac Structural Anomalies and Repair
- Lipid metabolism and biosynthesis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
The University of Texas Health Science Center at San Antonio
2025
University of Central Florida
2019-2023
Oregon Health & Science University
2014-2022
Mid Yorkshire Hospitals NHS Trust
2022
University of Florida
2020
Mayo Clinic
2016-2019
Mayo Clinic in Florida
2017-2018
WinnMed
2016-2018
Pulmonary and Critical Care Associates
2018
Mayo Clinic in Arizona
2016-2017
Dendritic cells (DCs) orchestrate the initiation, programming, and regulation of anti-tumor immune responses. Emerging evidence indicates that tumor microenvironment (TME) induces dysfunctional tumor-infiltrating DCs (TIDCs), characterized with both increased intracellular lipid content mitochondrial respiration. The underlying mechanism, however, remains largely unclear. Here, we report fatty acid-carrying tumor-derived exosomes (TDEs) induce to promote evasion. Mechanistically, peroxisome...
Purpose Optimization of the clinical management screen-detected lung nodules is needed to avoid unnecessary diagnostic interventions. Herein we demonstrate potential value a novel radiomics-based approach for classification indeterminate nodules. Material and methods Independent quantitative variables assessing various radiologic nodule features such as sphericity, flatness, elongation, spiculation, lobulation curvature were developed from NLST dataset using 726 (all ≥ 7 mm, benign, n = 318...
Optimal strategies to detect early interstitial lung disease (ILD) are unknown. ILD is frequently subpleural in distribution and affects elasticity. Lung ultrasound surface wave elastography (LUSWE) a noninvasive method of quantifying superficial tissue elastic properties. In LUWSE handheld device applied at the intercostal space vibrates chest set frequency, velocity measured by an probe 5 mm away same space. We explored LUWSE's ability correlated LUSWE with physiological, quantitative,...
A growing body of evidence supports the use bedside ultrasound for core Internal Medicine procedures and increasingly as augmentation physical exam. The literature also that trainees, both medical students residents, can acquire these skills. However, there is no consensus on training approach.To implement study effectiveness a high-yield expedited curriculum to train internal medicine interns examination procedures.The was conducted at metropolitan, academic center included 33 interns.This...
Purpose: This study assessed a novel diabetes mellitus (DM) rating scale in relation to its utility reducing Descemet membrane endothelial keratoplasty (DMEK) tissue preparation failure. Methods: A 5-point DM was defined, which 1 demonstrated relatively good health associated with and 5 represented comorbidities DM. chart review from consecutive donors who had at least prepared for DMEK performed. Using the donor profile, first processed each categorized according severity if passed or...
Abstract Computer-Aided Nodule Assessment and Risk Yield (CANARY) is quantitative imaging analysis software that predicts the histopathological classification post-treatment disease-free survival of patients with adenocarcinoma lung. CANARY characterizes nodules by distribution nine color-coded texture-based exemplars. We hypothesize computed tomography (CT) tumor tumor-free surrounding lung facilitates non-invasive identification clinically-relevant mutations in adenocarcinoma....
Lung adenocarcinoma (ADC), the most common lung cancer type, is recognized increasingly as a disease spectrum. To guide individualized patient care, non-invasive means of distinguishing indolent from aggressive ADC subtypes needed urgently. Computer-Aided Nodule Assessment and Risk Yield (CANARY) novel computed tomography (CT) tool that characterizes early ADCs by detecting nine distinct CT voxel classes, representing spectrum lepidic to invasive growth, within an ADC. CANARY...
A lung ultrasound surface wave elastography (LUSWE) technique is developed for assessing interstitial disease (ILD). In LUSWE, a 0.1 second harmonic vibration generated on the chest wall of subject using handheld vibrator. An probe aligned with indenter in same intercostal region to measure speed lung. human examined sitting position. The tested at total volume. upper anterior lungs are through space mid-clavicular line. lower lateral mid-axillary line and posterior mid-scapular prospective...