A5038269365- Hemoglobinopathies and Related Disorders
- Malaria Research and Control
- Child Nutrition and Water Access
- Autism Spectrum Disorder Research
- Epilepsy research and treatment
- Renal Diseases and Glomerulopathies
- Acute Kidney Injury Research
- Pharmacological Effects and Toxicity Studies
- Metabolism and Genetic Disorders
- Global Maternal and Child Health
- Family and Disability Support Research
- Autopsy Techniques and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Iron Metabolism and Disorders
- Child Development and Digital Technology
- Digital Imaging for Blood Diseases
- Attention Deficit Hyperactivity Disorder
- Asthma and respiratory diseases
- Mosquito-borne diseases and control
- Infectious Encephalopathies and Encephalitis
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Anesthesia and Pain Management
- Chronic Kidney Disease and Diabetes
- Genetics and Neurodevelopmental Disorders
Lagos University Teaching Hospital
2012-2025
University of Lagos
2012-2023
Federal Neuro Psychiatric Hospital
2017-2019
University of California, Davis
1994
<h3>Objective</h3> To investigate the prevalence, profile and predictors of severe malnutrition in children with congenital heart defects (CHDs). <h3>Design</h3> Case–control, observational study. <h3>Setting</h3> Tertiary teaching hospital Lagos, Nigeria (March 2006 to March 2008). <h3>Participants</h3> Children aged 3–192 months uncorrected symptomatic CHD healthy controls, frequency matched for age sex. <h3>Main outcome measures</h3> Prevalence based on WHO/National Center Health...
Background The modest decline in child mortality Africa raises the question whether pattern of diseases associated with acute kidney injury (AKI) children Nigeria has changed. Methods A database children, aged between one month and 16 years, AKI (using modified pediatric RIFLE criteria) was reviewed. cause defined as major underlying disease. clinical laboratory features who survived were compared to those died. Results Of 4 015 admitted into Lagos University Teaching Hospital July 2010...
Congenital malaria is increasingly reported among babies born to mothers continually residing in endemic areas. Given the high morbidity and mortality associated with it pertinent determine its current status newborns Lagos, Nigeria. The aim was incidence of congenital newborn delivered at Lagos University Teaching Hospital also frequency parasitaemia their placentae. A cross-sectional study attending antenatal clinic done. Sociodemographic clinical characteristics were documented. Samples...
Insufficient data to guide the authorities responsible for resource allocation and a focus on communicable diseases increase challenges of care children with kidney disease in resource-constrained settings like ours. This study was performed aim describe current spectrum pediatric nephrology tertiary hospital Sub-Saharan Africa highlight encountered their care. A 4-year retrospective review renal admissions carried out overall prevalence, disease-specific prevalence mortality rates were...
Congenital malaria is an important cause of morbidity and mortality in newborns. Signs symptoms congenital are non-specific could be confused with Neonatal sepsis. There has been a recent decline burden worldwide attributed to new strategy recommended by the WHO including use intermittent preventive treatment pregnancy using Sulfadoxine-Pyrimethamine (IPT-SP) during pregnancy, long lasting insecticide treated nets, case management Artemisinin-based combination therapy etc. This study sets...
The major pathology in sickle cell anaemia (SCA) is sickling of red cells due to the precipitation reduced haemoglobin. We report our experience with extract Cajanus cajan as a possible antisickling agent by determining changes, if any, clinical and laboratory features disease patients given single-blind placebo-controlled study. One hundred steady-state SCA were randomized into treatment placebo arms. extract/placebo administered twice daily subjects. Weight, hepatosplenomegaly, blood...
Introduction International professional groups are supporting the training of physicians in developing countries nephrology, including peritoneal dialysis (PD). This report documents impact such efforts provision manual PD for children with acute kidney injury (AKI) a public hospital Lagos, Nigeria. Methods Medical records all AKI managed between July 2010 and March 2013 were reviewed. Results Seventeen mean (SEM) age 3.8 (0.8) years received 0 - 18 days; about half infants. was provided...
Recent reports from both Caucasian and black populations suggest changes in steroid responsiveness of childhood nephrotic syndrome. This study was therefore undertaken to determine the features sensitivity pattern a cohort children with Records managed for syndrome January 2008 April 2013 were reviewed. Details including age, response treatment, renal histology analysed. There 108 (median age: 5.9 years, peak: 1-2 years), 90.2% whom had idiopathic Steroid 82.8% among but 75.9% overall....
Background: In this study, we sought to evaluate the influence of sociodemographic factors, ie, age, sex, socioeconomic status, maternal education, and human immunodeficiency virus (HIV) on cognitive performance in school-aged HIV-infected Nigerian children. Methods: Sixty-nine HIV-positive children aged 6–15 years were matched with 69 HIV-negative control for age sex. The subdivided purpose analysis into two developmental stages using Piaget’s staging, concrete operational stage (6–11...
Autism Spectrum Disorder (ASD) is a globally prevalent neurodevelopmental disorder for which early diagnosis and intervention the mainstay of management. In African continent, limited data available regarding non-clinic based samples. Lack information to caregivers inadequate skilled manpower often limit detection access few though under resourced services in community. Community screening can be an important drive create awareness improve dissemination those living with this disorder. This...
Introduction: In resource-constraint regions of the world, spectrum childhood diseases is changing, creating a need to clearly define epidemiology severe acute kidney injury (AKI). Methods: Medical records children aged between 1 month and 17 years with stage 3 AKI in tertiary hospital were reviewed. Results: Ninety-one children, comprising 63 (69.2%) males 26 (28.6%) infants, studied. Majority (75.8%) had at point hospitalization. Sepsis (41.8%), primary (PKD; 29.7%) malaria (13.2%) most...
Wilson disease is rarely reported among African children. This report describes the second case of a Nigerian child with in three decades. An eight-year-old boy presented generalized oedema and ascites proteinuria. Over next weeks he developed conjugated hyperbilirubinaemia, severe coagulopathy prominent extrapyramidal features consisting rigidity, tremors at rest action, shuffling gait, slurred speech emotional lability. Slit-lamp examination his eyes revealed Kayser-Fleischer rings...
Context and setting Advances in information technology biomedical research have resulted an expanded constantly changing literature of variable quality clinical relevance. This has the need to teach medical students skills self-directed management critical appraisal. Evidence-based medicine (EBM) principles been widely accepted as efficient strategies for accomplishing these goals incorporated into many school curricula. Why idea was necessary In sub-Saharan Africa, teaching EBM is rarely...
The role of oxidative stress has been identified in the development autism spectrum disorder (ASD), and polymorphisms glutathione S-transferase have associated with some diseases linked to stress. Hence, we evaluated serum levels markers investigated genetic autism.Forty-two children clinically diagnosed ASD using Diagnostic Statistical Manual for Mental Disorders (DSM-5) criteria a clinical interview were included study. Twenty-three age-matched controls without any known...
The ophthalmological findings in 91 Nigerian children with homozygous sickle cell anemia is reported. While the most constant sign was abnormality of conjunctival vasculature, seen 74(81%) patients, retinal lesions were found a total 53(58%) patients. Only tortuosity major vessels some patients but several others had more than one type lesion.
The clinical course of steroid-sensitive nephrotic syndrome (SSNS) among Nigerian children has rarely been reported; this makes prognostication difficult.The objective was to determine the frequency relapses including frequent (FR) and steroid-dependence (SD) in a cohort with SSNS. A secondary identify demographic factors associated relapse these children.Medical records SSNS Tertiary Hospital Nigeria were reviewed. Children onset (NS) at age <1-year, follow-up period <12 months causes NS...
Abstract This study investigated the attitudes of dental and medical students toward disability issues in Nigeria. The setting was College Medicine, University Lagos (CMUL), Idi-Araba, Lagos, researchers surveyed two groups 500-level (i.e., 142 42 students). Participants voluntarily anonymously completed a survey July 2013 after year-long exposure to disabilities class modules community-based experiences. An exploratory factor analysis conducted. found three factors, namely: caring for...
Objective: Developmental disorders with or without associated neuropsychiatric complications continue to be one of the major health problems in Africa. The grossly inadequate management/ rehabilitative facilities further worsen this. A prospective study aimed at finding types developmental and among children aged ≤15 years that presented disorder centers over 36 month duration. Methods: was carried out paediatric child psychiatric clinics as well Electroencephalographic (EEG) unit two...