Zhimei Tian

ORCID: 0000-0002-1738-7454
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Animal Nutrition and Physiology
  • Meat and Animal Product Quality
  • Gut microbiota and health
  • Biochemical effects in animals
  • Diamond and Carbon-based Materials Research
  • Ginger and Zingiberaceae research
  • Metabolomics and Mass Spectrometry Studies
  • Adipose Tissue and Metabolism
  • Food Quality and Safety Studies
  • Muscle metabolism and nutrition
  • Nanoparticle-Based Drug Delivery
  • Phytochemicals and Antioxidant Activities
  • GABA and Rice Research
  • Pharmacological Effects and Assays
  • Tea Polyphenols and Effects
  • Aquaculture Nutrition and Growth
  • Phytoestrogen effects and research
  • Protein Hydrolysis and Bioactive Peptides
  • Pharmacological Effects of Natural Compounds
  • Peroxisome Proliferator-Activated Receptors
  • Probiotics and Fermented Foods
  • Fermentation and Sensory Analysis
  • Boron Compounds in Chemistry
  • Ginseng Biological Effects and Applications
  • Sulfur Compounds in Biology

Guangdong Academy of Agricultural Sciences
2016-2025

Ministry of Agriculture and Rural Affairs
2018-2025

Jiangxi Agricultural University
2025

Innovation Team (China)
2025

Key Laboratory of Guangdong Province
2018-2024

Guangdong Inspection and Quarantine Technology Center (China)
2020-2024

Poultry Research Institute
2024

Shanxi University
2013-2015

Background: This study investigated the use of nanodiamond particles (NDs) as a promising material for drug delivery in vivo and vitro. Methods: HepG2 cells (a human hepatic carcinoma cell line) were used to determine characteristics nanodiamond-doxorubicin complex (ND-DOX) when taken up by vitro using laser scanning confocal microscopy dialysis experiments. We also compared survival rate histopathology tumor-bearing mice after treatment with NDs or ND-DOX vivo. Results: In investigation...

10.2147/ijn.s54864 article EN cc-by-nc International Journal of Nanomedicine 2014-02-01

Background/Aims: There has been increasing recent attention on the antioxidative capacity of equol. This study tested effect equol oxidative stress induced by lipopolysaccharide (LPS) and regulation immunity in chicken macrophages. Methods: Chicken HD11 macrophages were challenged with LPS (100 ng/mL) alone or (±)equol (10, 20, 40, 80, 160 μmol/L) together for 24h. Evaluated responses included contents malondialdehyde (MDA) reduced glutathione (GSH), activities total superoxide dismutase...

10.1159/000430124 article EN cc-by-nc Cellular Physiology and Biochemistry 2015-01-01

This study evaluated the ability of Aspergillus niger and Trichoderma koningii to improve quality tea dregs (TDs) through solid-state fermentation as well value fermented (FTDs) produced for use bio-feed additives. After fermentation, FTDs differed in color structure. Fermentation with A . T increased contents crude protein, fiber, neutral detergent acid fiber TDs. Compared unfermented group, reducing sugar, total flavonoids, polyphenols, theasaponins were FTDs, while caffeine was completely...

10.1371/journal.pone.0260045 article EN cc-by PLoS ONE 2021-11-12

Reduced glutathione (GSH) is a main nonenzymatic antioxidant, but its effects and underlying mechanisms on growth intestinal health in weaned piglets still require further assessment. A total of 180 were randomly allotted to 5 groups: basal diet (CON), supplemented with antibiotic chlortetracycline (ABX), 50 (GSH1), 65 (GSH2), or 100 mg/kg GSH (GSH3). Results revealed that dietary GSH1, GSH2, ABX improved body weight the average daily gain piglets, decreased albumin content increased...

10.3390/antiox14010107 article EN cc-by Antioxidants 2025-01-17

This study investigated the effects of microenapsulated hydrolyzed tannins (MHTs) on growth performance and meat quality Zhongshan shelducks. A total 288 healthy shelducks with an average initial weight 1790.27 ± 0.14 kg were randomly divided into four groups through a 56 d experiment period fed basal diet supplemented 0 (CON), 400, 800, 1600 mg/kg MHTs, respectively. Results showed that 400 800 MHTs improved final body weight, daily gain, glutathione peroxidase activity, antioxidant...

10.3390/foods14050839 article EN cc-by Foods 2025-02-28

Aim: PEGylated fluorescent nanodiamond (FND) conjugated with Tf (FND-PEG-Tf) was investigated for targeted drug delivery. Materials & methods: Human hepatoma (HepG2) and normal (L-02) cell lines were used to investigate the difference in cellular uptake of FND-PEG-Tf its loading system. Nanoparticle evaluated by flow cytometry laser scanning confocal microscopy. Results: showed highly specific TfR-mediated HepG2 cells, relative negative controls (L-02 cell), which a strong correlation among...

10.4155/tde.14.17 article EN Therapeutic Delivery 2014-05-01

The accumulation of reactive oxygen species (ROS) triggers oxidative stress in cells by oxidizing and modifying various cellular components, preventing them from performing their inherent functions, ultimately leading to apoptosis autophagy. Glutathione (GSH) is a ubiquitous intracellular peptide with multiple functions. In this study, hydrogen peroxide (H2O2)-induced damage model IPEC-J2 was used investigate the protection mechanism exogenous GSH against stress. results showed that...

10.3390/molecules27082416 article EN cc-by Molecules 2022-04-08

Abstract This study aimed to assess the efficacy of fermented okara on performance and meat quality, explore feasibility its partial substitution for corn‐soybean meal in pig production. A total 48 pigs (Duroc × Landrace Yorkshire) with an average body weight 58.60 ± 0.65 kg were randomly assigned 2 groups, Control group Fermented (FO) group. There 8 replicate pens each 3 per treatment. fed a basal diet, treatment diet supplemented FO throughout 55‐d experimental period. Results showed that...

10.1002/fsn3.1857 article EN cc-by Food Science & Nutrition 2020-09-07

Mulberry leaf extract (MLE) extracted from mulberry leaves is rich in a variety of bioactive ingredients and can be used as feed additives weaned piglets. The present study was conducted to evaluate the effects dietary MLE supplementation on intestinal barrier function, colon microbial numbers metabolites piglets.MLE increased villus height height/crypt depth ratio jejunum ileum (P < 0.05), mRNA expression ZO-1, Claudin-1 MUC-2 ileal mucosa decreased serum level lipopolysaccharide 0.01)....

10.1002/jsfa.12254 article EN Journal of the Science of Food and Agriculture 2022-10-10

This study investigated whether dietary supplementation with magnolol affects growth performance, anti-inflammatory abilities, serum and muscle amino acid profiles, metabolisms in growing pigs. A total of 42 seventy-days-old barrows (Duroc × Landrace Yorkshire) were randomly allocated into two groups: Con, control group (basal diet); Mag, diet supplemented 400 mg/kg magnolol). The results revealed that had no effect (p > 0.05) on performance. However, remarkably increased < the content...

10.3390/ijms241813952 article EN International Journal of Molecular Sciences 2023-09-11

Mulberry leaves are rich in nutrients but contain anti-nutrient factors that hinder their digestion and absorption. Feeding animals with mulberry directly could harm health. The microbial fermentation of reduce anti-nutritional factors’ content improve nutritional value. Sequencing analyzing before after showed increased the relative abundance Pediococcus, Bradyrhizobium, Hydrotalea, Rhodanobacteria, decreased Enterobacter. Fermentation improved quality by rebuilding bacterial community....

10.3390/fermentation10040215 article EN cc-by Fermentation 2024-04-15

This study aimed to investigate the effects of long-term feeding diets supplemented with antibiotics and Lactobacillus reuteri 1 (LR1) on growth performance, intestinal digestion absorption in pigs. The results showed that both LR1 increased body weight piglets after 42-d (P < 0.05), a tendency promote performance growing-finishing significantly improved jejunal ileal mucosal morphology expression glucosidase cholecystokinin, digestive enzymes nutrient transporters. decreased lactase, B0 +...

10.1016/j.jff.2020.104010 article EN cc-by-nc-nd Journal of Functional Foods 2020-05-21

This study investigated the effects of guanidine acetic acid (GAA) supplementation on growth performance, carcass traits, and meat quality in Tibetan pigs. A total 18 male pigs (21.35 ± 0.99 kg) were randomly assigned to control (basal diet) GAA diet + 800 mg/kg GAA) groups for 125 days. Growth pigs, chemical composition Longissimus thoracis (LT) not altered by GAA. In LT, compared group, dietary increased superoxide dismutase activity, transcripts stearoyl CoA desaturase ( SCD ) fatty...

10.3389/fvets.2022.998956 article EN cc-by Frontiers in Veterinary Science 2022-10-11
Coming Soon ...