Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. The chance of cure very limited due to treatment-refractory disease course with frequent recurrences despite aggressive multimodality management. In this retrospective study, we evaluated treatment outcomes hypofractionated stereotactic radiotherapy (HFSRT) management recurrent GBM and report our single-center experience.Twenty-eight patients receiving HFSRT for between September 2008 February 2014 were...

In this retrospective analysis, we evaluated the use of stereotactic body radiation therapy in management adrenal metastases from non-small cell lung cancer and report our single center experience.Fifteen patients (9 male, 6 female) with 17 referred to Gulhane Military Medical Academy Radiation Oncology Department were treated using active breathing control-guided between December 2009 October 2013. Dose per fraction was 10 Gy deliver a total dose 30 over 3 consecutive days for all...

Lung cancer presents a major public health concern in our country and around the globe. Radiotherapy is one of main treatment modalities for lung management several years. This study aims to evaluate differences dosimetric radiobiological parameters dose distributions Planning Target Volume (PTV) organs at risk (OAR) patients with tumors using different Treatment System (TPS) algorithms Volumetric Modulated Arc Therapy (VMAT) technique. was accomplished group 19 who were treated clinic. In...

Background/Aim. Management of patients with recurrent glioblastoma (GB) comprises a therapeutic challenge in neurooncology owing to the aggressive nature disease poor local control despite combined modality treatment. The majority cases recur within highdose radiotherapy field limiting use conventional techniques for re-irradiation due potential toxicity. Stereotactic radiosurgery (SRS) offers viable noninvasive option palliative treatment GB as sophisticated improved setup accuracy allowing...

Cavernous malformations (CM), also named as "cavernomas," "cavernous angiomas," or hemangiomas" are low-flow vascular lesions deemed to be in relation with developmental venous anomalies and capillary telangiectasias. 1 CM have a well-established tendency bleed.Although intracranial hemorrhages usually mild severity, severe may lead significant disability death.The rationale for using stereotactic radiosurgery (SRS) the management of is preventing any Evaluation linear accelerator...

Aims and Background Although mostly benign slow-growing, glomus jugulare tumors have a high propensity for local invasion of adjacent vascular structures, lower cranial nerves the inner ear, which may result in substantial morbidity even mortality. Treatment strategies include surgery, preoperative embolization followed by surgical resection, conventionally fractionated external beam radiotherapy, radiosurgery form stereotactic or radiation therapy, combinations these modalities. In present...

Stereotactic radiosurgery is being increasingly used for the treatment of both benign and malignant disorders such as brain metastasis, spinal cord tumors, intracranial blood vessel abnormalities neurological/functional problems Parkinson’s disease, epilepsy, obsessive-compulsive disorder trigeminal neuralgia. The purpose this report was to present our experience at Department Radiation Oncology Gulhane Military Medical Faculty using linear accelerator-based stereotactic technology examine...

The purpose of this study is to evaluate the use linear accelerator (LINAC)-based stereotactic body radiotherapy (SBRT) boost with multileaf collimator technique after pelvic (RT) in patients endometrial cancer.Consecutive cancer treated using LINAC-based SBRT RT were enrolled study.All had undergone surgery including total abdominal hysterectomy and bilateral salpingo-oophorectomy ± pelvic/paraortic lymphadenectomy before RT.Prescribed external dose was 45 Gray (Gy) 1.8 Gy daily...

The purpose of this study is to evaluate the effect Active Breathing Control-moderate deep inspiration breath-hold (ABC-mDIBH) on tumor motion and critical organ doses in non-small cell lung cancer (NSCLC) radiotherapy. 23 patients with locally advanced NSCLC were included study. All scanned at free breathing ABC-mDIBH for radiation treatment planning. 3 separate plans generated each patient including one plan uniform margins, 3-dimensional non-uniform margins determined by Cone Beam...

The aim of the study was to evaluate feasibility, toxicity and effectiveness active breathing control-guided stereotactic body radiotherapy in management pulmonary oligometastases.Between June 2010 2012, 20 patients (13 males, 7 females) with 31 metastases referred Department Radiation Oncology, Gulhane Military Medical Academy were treated using radiotherapy. Response Evaluation Criteria Solid Tumors Common Terminology for Adverse Events used assessment treatment response toxicity,...

Aims and background The aim of the study was to examine feasibility non-invasive image-guided radiosurgery improve patient comfort quality life in stereotactic planning treatment patients with brain metastasis. Precise immobilization is a rule thumb for radiosurgery. Non-invasive techniques have potential improved compared invasive procedures. Methods design A total 92 lesions from 42 metastasis were included study. After thermoplastic mask bite-block unlike frame-based procedure, computed...

The primary goal of treatment for vestibular schwannoma is to achieve local control without comprimising regional cranial nerve function. Stereotactic radiosurgery has emerged as a viable therapeutic option schwannoma. aim the study report our 15-year single center experience using linear accelerator-based stereotactic in management patients with schwannoma.Between July 1998 and January 2013, 68 unilateral were treated at Department Radiation Oncology, Gulhane Military Medical Academy. All...

There is scant data on the utility of repeated radiosurgery for management locally recurrent brain metastases after upfront stereotactic (SRS). Most studies have used single-fraction SRS radiosurgery, and use fractionated (f-SRS) in this setting has been poorly addressed. In study, we assessed f-SRS failed report our single-center experience.A total 30 patients receiving at department between September 2011 2017 were retrospectively evaluated local control (LC), toxicity, overall survival...

Meningiomas are the most common intracranial benign tumors. While an indolent natural history is typical for meningiomas, a wide spectrum of symptoms may occur depending on lesion location and proximity to critical neurovascular structures. A multidisciplinary approach be warranted optimal management meningiomas. In scarcity prospective, randomized controlled studies dictate treatment algorithms, decision making based primarily mostly retrospective data.

Aims and background The aim of the study was to evaluate dosimetric impact active breathing control-moderate deep inspiration breath-hold (ABC-mDIBH) technique on normal tissue sparing in locally advanced left-sided breast cancer radiotherapy. Methods design Twenty-seven consecutive patients with referred our department for adjuvant radiotherapy were enrolled study. Each patient scanned at free ABC-mDIBH radiation treatment planning. Two separate plans generated without investigate Results...

Aims and Background Symptomatic, massive splenomegaly is a debilitating complication of myeloproliferative disorders. In the study, we evaluated use contemporary, individualized radiotherapeutic approach for splenic irradiation, including 3-dimensional computed tomography-based treatment planning, margins based on motion assessment, online setup verification with volumetric image guidance at each fraction, adaptive radiation planning to account changes in size during fractionated...

Infiltration of the breast by leukemic cells is uncommon but may manifest as an oncological emergency requiring prompt management. Extramedullary relapse T-cell acute lymphoblastic leukemia (T-ALL) within exceedingly rare and there paucity data in literature regarding this entity. No consensus exists on management isolated extramedullary relapses T-ALL. Herein, we report a case T-ALL treated with breathing adapted radiation therapy (BART) using active control (ABC) system.The patient was...

Adjuvant radiotherapy after surgical resection is used for the treatment of patients with brain metastasis. In this study, we assessed use adjuvant hypofractionated stereotactic (HFSRT) to cavity management metastasis.A total 28 undergoing their metastasis were treated using HFSRT cavity. A dose 25-30 Gray (Gy) was delivered in 5 consecutive daily fractions. Patients retrospectively toxicity, local control, and survival outcomes. Kaplan-Meier method log-rank test statistical analysis.Median...