A5000625019- Advanced Radiotherapy Techniques
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Sarcoma Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Endometrial and Cervical Cancer Treatments
- Head and Neck Cancer Studies
- Bone Tumor Diagnosis and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Cervical Cancer and HPV Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer and Skin Lesions
- Brain Metastases and Treatment
- Bladder and Urothelial Cancer Treatments
- Gastrointestinal Tumor Research and Treatment
- Meningioma and schwannoma management
- Advances in Oncology and Radiotherapy
- BRCA gene mutations in cancer
- Testicular diseases and treatments
- Ear and Head Tumors
- Lung Cancer Research Studies
Karadeniz Technical University
2013-2022
Acıbadem University
2019
Okmeydanı Eğitim ve Araştırma Hastanesi
1995-2014
The aim of the present study was to compare effects melatonin and genistein on radiation-induced nephrotoxicity (RIN). A total 70 Swiss Albino mice were divided into 7 groups. Five control groups defined, which sham irradiation (C, G1), radiation therapy only (RT, G2), (M, G3), (G, G4) polyethylene glycol-400 (G5), respectively. co-treatment RT plus (RT+M, G6) (RT+G, G7) Irradiation applied using a cobalt-60 teletherapy machine (80-cm fixed source-to-surface distance, 2.5-cm depth)....
Adenoid cystic carcinoma (ACC) is a rare malignant tumor of the breast that occurs in <0.1% all patients diagnosed with cancer. The mean patient age at time diagnosis 50-60 years. Typically, presents as subareolar mass or pain breast. While radiological appearances ACC are generally non-specific, can be made on fine-needle aspiration cytology. In present study, 58-year-old female was admitted to Department Radiation Oncology (Karadeniz Technical University, Faculty Medicine, Trabzon, Turkey)...
The aim of this study was to assess the feasibility sparing contralateral hippocampus during partial brain radiotherapy in high grade gliomas. 20 previously treated patients were replanned 60 Gy 30 fractions with intensity-modulated (IMRT) and volumetric modulated arctherapy (VMAT) using following planning objectives: 100 % PTV covered by 95% isodose without violating organs at risk (OAR) hot spot dose constraints. For each, standard plans generated, as well IMRT VMAT which spared...
The aim of this study was to identify a rational strategy for the selection multi-beam IMRT in patients with right breast cancer through comparison dosimetric parameters planning target volume (PTV) and organs at risk (OARs) using five different radiotherapy modalities. This retrospective computed tomography scans from ten early-stage who had been treated previously. Three dimensional conformal (3DCRT), forward-planned (for-IMRT), inverse-planned (inv-IMRT), helical tomotherapy (HT),...
In this study, we used the concept of organ-equivalent dose (OED) to evaluate excess absolute risk (EAR) for secondary cancer in various organs after radiation treatment breast cancer.Using CT data set 12 patients, generated three different whole-breast plans using 50 Gy 2 fractions: three-dimensional conformal radiotherapy with a field-in-field (FinF) technique, intensity modulated therapy (IMRT), and volumetric arc (VMAT). The OEDs were calculated from differential dose-volume histograms...
The aim of this study was to evaluate the prognosis patients with stage IA-IIB cervical carcinoma and investigate a possible correlation histology prognosis.Two hundred fifty one adenocarcinoma squamous cell (SCC) for FIGO (International Federation Gynecology Obstetrics) uterine carcinomas at Radiation Oncology Clinic GH Okmeydani Training Research Hospital between January 1996 December 2006 were selected, analyzed retrospectively evaluated in terms general characteristics survival....
To review clinical characteristics, treatment outcomes and prognostic factors in patients with parotid gland tumors treated surgery postoperative radiotherapy.We retrospectively reviewed 69 tumors, a median follow-up of 52 months (range, 2-228 months). radiotherapy dose 60Gy 30-69 Gy).There were 24 (35%) females 45 (65%) males, at ratio 1/1.9. Median age presentation was 58.9±17.2 (range 13-88) years. The most common histology adenoid cystic carcinoma (33%) mucoepidermoid (28%). mean overall...
The aim of the study is to evaluate clinical features patients with low-risk stage I endometrium cancer, who received adjuvant therapy or followed observation only and analyse effects known prognostic factors in this group patients.A total 246 (median age: 53, range: 31-77) endometrial were just postoperatively (156 patients) radiotherapy (90 between 1996 2007 reviewed retrospectively.Local recurrence was detected four patients, distant metastasis occurred seven two had both local...
Abstract In this study, the dose schedule efficacy, safety and late adverse effects of stereotactic radiosurgery (SRS) were evaluated for patients with symptomatic cavernomas who not eligible surgery treated SRS. Between January 2013 December 2018, 53 using SRS CyberKnife® system. Patients’ diseases deeply located or in subcortical functional brain regions. addition to bleeding, 23 (43.4%) had epilepsy, 12 (22.6%) neurologic symptoms 16 (30.2%) severe headaches. The median volume was 741...
Giant cell tumors (GCTs) are usually found in the epiphysis of long bones, and represent ~5% all bone tumors. Only <1% GCTs localized cranium. When cranium, commonly observed sphenoid or temporal rarely parietal frontal bones. Occipital posterior fossa involvement is an extremely rare occurrence. The current study presents a 22‑year‑old female patient was admitted to Department Radiation Oncology (Karadeniz Technical University, Faculty Medicine, Trabzon, Turkey) with complaints neck pain...
Abstract The aim of the present study was to compare radiation dose received by thyroid gland using different radiotherapy (RT) techniques with or without constraint (DC) for breast cancer patients. Computerized tomography (CT) image sets 10 patients were selected. All treated originally opposite tangential field‐in field (FinF) chest wall and anteroposterior fields ipsilateral supraclavicular field. not contoured on CT images at time original scheduled treatment. Four new treatment plans...
Olfactory neuroblastoma (ON) is a rare type of malignant neoplasm originating from the olfactory neuroepithelial cells nasal cavity. ON also known as esthesioneuroblastoma or neuroendocrine carcinoma. The malignancy accounts for <3% tumors in Through cavity, may infiltrate sinuses, orbit and cranium. tumor characterized by pattern slow growth local recurrences. Treatment options are surgical excision surgery combined with radiotherapy (RT) and/or chemotherapy combination treatment. present...
Although soft tissue constitutes half of the body weight, soft-tissue sarcomas (STSs) are less common than any other types tumors.In this retrospective study, prognostic factors and clinical courses 64 patients with extremity STSs treated at our clinic between 1996 2012 were investigated.Of included in 35 (55%) male 29 (45%) female. By end follow-up, remained alive while deceased. The overall survival (OS) time was 89.1 months, their 1-, 3-, 5-, 10-year rates 82.8%, 69.3%, 51.6%, 39.4%,...
<b>Background</b> : 5-Flourouracil (FU)-based chemotherapy (CT) and concurrent 45 Gy radiotherapy (RT) is one of the standard postoperative approaches currently used in gastric carcinoma. The high toxicity rates this treatment leads to interruption majority patients. In our study, we investigated discontinuation observed during FU-based chemoradiotherapy (CRT); retrospectively evaluated effect CRT other prognostic factors on local distant control survival. <b>Patients Methods:</b> A total...
The purpose of this study was to evaluate the prognostic factors affecting overall survival (OS), cause-specific (CSS), progression-free (PFS), and among patients undergoing adjuvant radiotherapy (RT) for stage-1 seminoma.Between August 1997 May 2013, 68 diagnosed with seminoma were retrospectively evaluated. median age 39 (24-74) years. All received RT after inguinal orchiectomy. Fifty-eight (85.3%) paraaortic RT; 10 (14.7%) dog-leg field RT. dose 23.4 (23.4-30.6) Gy.The follow-up period...
Head and neck cancers are rapidly proliferating relatively radiosensitive tumors. The increase in the number of daily fractions decrease total treatment time give promising results clinical practice. Patients Methods: 20 patients diagnosed with head cancer between August 2000 July 2001 participated this study. Median age was 63 years (range: 42-78). tumors were mainly located larynx (40%), hypopharynx (25%). Daily doses 1.5 Gy thrice a day 6-h intervals given on each 12 consecutive days...
5-fluoro-uracil (FU) is a common agent in postoperative chemoradiation gastric adenocarcinoma. However, FU not well tolerated significant proportion of patients. Capecitabine (CA) an orally administered fluoropyrimidine carbamate which preferentially converted to active 5-FU and one the agents used instead such cases. We compared toxicity, local distant control survival rates with or oral CA during course concurrent radiotherapy assess role FU.We conducted analysis survival, disease toxicity...