- Head and Neck Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Lung Cancer Treatments and Mutations
- Breast Cancer Treatment Studies
- Cancer Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Colorectal and Anal Carcinomas
- Radiation Therapy and Dosimetry
- Effects of Radiation Exposure
- Colorectal Cancer Surgical Treatments
- Cell death mechanisms and regulation
- Urinary and Genital Oncology Studies
- Lung Cancer Research Studies
- Bladder and Urothelial Cancer Treatments
- Oral health in cancer treatment
- Radiomics and Machine Learning in Medical Imaging
- Neuroendocrine Tumor Research Advances
- Carcinogens and Genotoxicity Assessment
- Advances in Oncology and Radiotherapy
- Pancreatic and Hepatic Oncology Research
- MRI in cancer diagnosis
- Cancer Cells and Metastasis
- Cancer and Skin Lesions
- Metastasis and carcinoma case studies
Yaşar University
2024
Bursa Uludağ Üni̇versi̇tesi̇
2002-2015
Denizli Devlet Hastanesi
2015
Şişli Etfal Eğitim ve Araştırma Hastanesi
2015
Radiation Oncology Associates
2011
Memorial Sisli Hospital
1992
Post-treatment endocrine disturbances are common in cancer patients who have received radiotherapy or chemotherapy. The objective of this study was to evaluate the thyroid functions long-term survivors pediatric Hodgkin's lymphoma treated with chemotherapy and radiotherapy.Thyroid 55 (M/F:2.05/1) complete remission were evaluated retrospectively.The mean age at diagnosis 10.35±4.09 (range: 2.83-17) years follow-up period 5.54±3.68 0.92-13.92) years. All chemotherapy; a total 50 (90.9%)...
We aimed to determine predictive factors affecting cosmetic results after breast conserving management in cancer. Data on 96 patients with 97 cancer cases, who had been admitted Uludağ University M.A. Radiotherapy Center between October 1995 and December 1998 managed breast-conserving treatment, were analysed the outcome. Possible cosmesis grouped as patient-related, tumor-related treatment-related. Mann-Whitney U test was used univariate analyses whereas logistic regression multivariate...
The status of the axillary lymph nodes at time diagnosis has been accepted as one most important prognostic factors for overall and disease-free survival patients with breast cancer. aim our study was to determine which influence node involvement in invasive cancer.The data presented here were obtained from 344 who treated cancer Department Radiation Oncology, Uludağ University Medical College, Bursa, Turkey. Possible categorized patient related tumor related. Mann-Whitney U test used...
Aims and background To evaluate the efficacy tolerability of a new treatment approach including induction chemotherapy (CT) concurrent chemoradiotherapy (CRT) in unresectable, locally advanced pancreatic cancer (LAPC). Patients methods Twenty-four patients with LAPC were enrolled study. They first received CT consisting 5-fluorouracil (5FU) (500 mg/m 2 ) gemcitabine (1000 ), which given weekly for 3 weeks every 4. showing response or disease stabilization after cycles CRT external beam...
In this study, we aimed to investigate the benefits of 18F-deoxyglucose positron emission tomography/computed tomography (FGD-PET/CT) imaging for staging and radiotherapy planning in patients with head neck cancer undergoing definitive radiotherapy.Thirty-seven who had undergone PET/CT at Uludag University Medical Faculty Department Radiation Oncology were investigated order determine role planning.The median age patient group 32 males 5 females was 57 years (13-84years). The stage remained...
To evaluate the effect of bcl-2 expression on local control and overall survival patients with early stage laryngeal cancer treated radiotherapy alone.We included 53 Tis, T1, T2 who were irradiated in our department. Paraffin blocks all biopsy specimens subjected to immunohistochemical analysis a oncoprotein mouse clone 124 Scytek kit.The mean follow-up time was 61 months (range, 7-166). Local-regional recurrence observed 10 (19%) patients. Forty-three (81%) had negative staining, 5 (9%) + 3...
Aims and background To evaluate the effect of bcl-2 expression on local control overall survival patients with early stage laryngeal cancer treated radiotherapy alone. Methods study design We included 53 Tis, T1, T2 who were irradiated in our department. Paraffin blocks all biopsy specimens subjected to immunohistochemical analysis a oncoprotein mouse clone 124 Scytek kit. Results The mean follow-up time was 61 months (range, 7–166). Local-regional recurrence observed 10 (19%) patients....
In this study, we investigated the genotoxic effect of taxol, radiation, or taxol plus radiation on highly proliferative normal tissue-bone marrow cells Swiss albino mice. Swiss-albino mice, 3-4 months old, were used in study. Taxol was administered bolus intravenously through tail vein. Radiation given by using a linear accelerator. There four treatment categories, which had total 34 groups. Each group consisted five animals. The first control category that one (n = 5). second alone, three...
Objective: We aimed to investigate the effect of amifostine on acute and late side effects, its tolerability in head neck cancer patients treated with radiotherapy (RT). Material Methods: The study included 87 primary cancers cervical lymph node metastases from unknown RT alone or combined chemotherapy (CT). Forty-one (47%) received (ART group) 46 (52%) without (RT group). were evaluated every week during treatment at month 1 2 after completion for effects 3, 6, 9, 12, 24 according SOMA/LENT...
The aim of this study is to obtain the optimum measurement method overcome dosimetric problems in small field dosimetry which very important Intensity Modulated Radio Therapy.In study, relative dose factors obtained by Farmer, Semiflex, PinPoint, Marcus PP ionisation chambers and thermoluminescence square fields between 1x1 -15x15 cm generated multi leaf collimator Siemens Artiste linear accelerator (6-15 MV) were researched.For each d=10 cm, measurements are performed thrice using 100 MU...
Purpose: To investigate the effects of epidermal growth factor receptor (EGFR), cytokeratin 19 (CK19), 20 (CK20) and survinin gene expression on local control (LC) overall survival (OS) in patients with locally advanced head neck cancer (LAHNC) who were administered radiotherapy (RT).Materials Methods: Twenty-six admitted to Uludag University Medical Faculty Department Radiation Oncology a diagnosis LAHNC (GIII-GIV) included this study.Gene was evaluated tumor tissues peripheral blood.RNA...
This study aims to evaluate our single center experience in patients with a salivary gland tumor receiving postoperative radiation therapy (RT).Between January 1996 and December 2011, the records of 34 who were operated referred clinic for adjuvant RT retrospectively analyzed. Radiation was applied primary lymphatics at median dose 60 Gy (54 Gy) 1.8-2 Gy/fraction.The follow-up 38 months (range, 3 204 months). The most common site involvement parotid 21 (62%), followed by submandibular 11...
Objective: Inflammatory response associated with radiation-induced lung injury (RILI) results in an increased 18F-fluorodeoxyglucose (FDG) uptake on positron emission tomography/computed tomography (PET/CT). In this study, we aimed to analyze the degree of FDG within specific isodose regions (IR) irradiated using standardized value (SUV) measurements, and correlate posttreatment radiotherapy (RT) dose parameters, patient characteristics imaging time interval after RT completion. Material...
This study aims to evaluate the efficacy chemoradiotherapy and surgical treatment in patients with hypopharyngeal cancer.Between January 2003 July 2009, 48 (31 males, 17 females; mean age 55.5±13.4 years; range 29 84 years) who were diagnosed cancer retrospectively evaluated. The assigned into surgery (n=17) (n=31) groups.The overall survival of advanced disease group was statistically higher than those group. recurrence rate 35.3% group, whereas it 41.4% group.Our results indicated that...