A5021177824- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Pulmonary Hypertension Research and Treatments
- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac Fibrosis and Remodeling
- Cardiac pacing and defibrillation studies
- Aortic aneurysm repair treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Signaling Pathways in Disease
- Coronary Interventions and Diagnostics
- Body Composition Measurement Techniques
- Cardiomyopathy and Myosin Studies
- Biomarkers in Disease Mechanisms
- Coronary Artery Anomalies
- Cardiac tumors and thrombi
- Advanced MRI Techniques and Applications
- Viral Infections and Immunology Research
Hospital Universitari Germans Trias i Pujol
2018-2025
Instituto de Salud Carlos III
2020-2024
Centro de Investigación en Red en Enfermedades Cardiovasculares
2019-2024
Vall d'Hebron Hospital Universitari
2023
Universitat Autònoma de Barcelona
2019-2020
Ascending aorta dilation and aortic valve degeneration are common complications in patients with bicuspid valve. Several retrospective studies have suggested the benefit of statins reducing these complications. This study aimed to determine whether atorvastatin treatment is effective growth diameters if it slows progression calcification.
Abstract Aims How the underlying etiology and pathophysiology of left ventricular (LV) hypertrophy affects LA remodeling function remains unexplored. The present study aims to investigate influence various hypertrophic phenotypes on function. Methods Results Patients with LV who underwent cardiac magnetic resonance (CMR) were compared a control group. CMR data analyzed retrospectively assess strain, volume, sphericity atrioventricular coupling index (LACI). Independent clinical associates...
Evidence regarding any association of HDL-particle (HDL-P) derangements and HDL-cholesterol content with cardiovascular (CV) death in chronic heart failure (HF) is lacking. To investigate the prognostic value HDL-P size (HDL-Sz) number cholesterol molecules per for CV HF patients. Outpatient patients were enrolled. Baseline number, subfractions HDL-Sz measured using 1H-NMR spectroscopy. The HDL-C/P ratio was calculated as over HDL-P. Endpoint death, non-CV competing event. 422 included...
Abstract Aims In low‐risk patients with severe aortic stenosis (AS), sutureless surgical valve replacement (SU‐SAVR) may be an alternative to transcatheter implantation (TAVI). The risk of heart failure hospitalization (HFH) after (AVR) in this population is incompletely characterized. This study aims investigate the incidence, predictors, and outcomes HFH undergoing SU‐SAVR versus TAVI. Methods results Patients referred for AVR between 2013 2020 at two centres were consecutively included....
Background: In asymptomatic severe aortic stenosis (ASAS), treatment decisions are made on an individual basis, and case management presents a clinical conundrum. Methods: We prospectively phenotyped consecutive patients with ASAS using echocardiography, exercise cardiac MRI biomarkers (NT-proBNP, high-sensitivity troponin T (hs-TnT) ST2) (n = 58). The primary endpoint was composite of cardiovascular death, new-onset symptoms, hospitalization, guideline-driven indication for valve...
To determine the risk of mortality and need for aortic valve replacement (AVR) in patients with low-flow low-gradient (LFLG) stenosis (AS).A longitudinal multicentre study including consecutive severe AS (aortic area [AVA] < 1.0 cm2) normal left ventricular ejection fraction (LVEF). Patients were classified as: high-gradient (HG, mean gradient ≥ 40 mmHg), normal-flow (NFLG, mmHg, indexed systolic volume (SVi) > 35 ml/m2) LFLG (mean SVi ≤ ml/m2).Of 1,391 patients, 147 (10.5%) had LFLG, 752...
Abstract Aims To assess the progression of disease and evolution main echocardiographic variables for quantifying AS in patients with severe low-flow low-gradient (LFLG) compared to other subtypes. Methods results Longitudinal, observational, multicenter study including consecutive asymptomatic (aortic valve area, AVA &lt; 1.0 cm²) normal left ventricle ejection fraction (LVEF ≥ 50%). Patients were classified according baseline echocardiography into: HG (high gradient; mean gradient 40...
This study aimed to examine the prevalence of atrial tricuspid regurgitation (ATR) and mitral (AMR) in setting fibrillation (AFib) identify variables related severity both types regurgitation.Cross-sectional evaluating data from transthoracic echocardiograms performed during 2019. We included patients with AFib examination, without primary valve disease or other significant heart disease.Four-hundred thirty-two fulfilled inclusion criteria (mean age 77.5±9.2 years, 49.1% women). observed ATR...
To assess the agreement between left ventricular end-diastolic diameter index (LVEDDi) and volume (LVEDVi) to define LV dilatation investigate respective prognostic implications in patients with heart failure (HF).
Journal Article Accepted manuscript From Left Ventricular Outflow Tract Obstruction to Mitral Get access Mireia Llevadot, MD, MD iCor Heart Institute, Department of Cardiology Search for other works by this author on: Oxford Academic PubMed Google Scholar Elena Ferrer-Sistach, PhD, PhD https://orcid.org/0000-0002-1795-2193 Lorenzo Niro, Luis Delgado, Cardiac Surgery; Hospital University Germans Trias i Pujol, Badalona, Spain Victoria Author correspondence: Delgado; Cardiology, Carretera de...
Abstract Background Discordant grading of severe aortic stenosis can result from a tight valve area (&lt;1cm2) with low transvalvular mean gradient (&lt;40 mmHg). Small annulus dimensions and flow status may contribute to discordant stenosis. However, the frequency patients small grading, along their characteristics outcomes after intervention, remains unknown. Purpose To investigate in evaluate clinical characteristics, as well transcatheter implantation (TAVI). Methods Patients an...
Abstract Funding Acknowledgements Type of funding sources: None. Background Although paradoxical low-flow low-gradient (LFLG) aortic stenosis (AS) has been considered a more severe form AS with worse prognosis than high-gradient (HG) AS, data on the natural history this entity are scant. Objectives To assess progression disease and evolution main echocardiographic variables for quantifying in patients LFLG compared to HG normal-flow (NFLG) AS. Methods A longitudinal, observational,...
Journal Article Corrected proof Transcatheter intervention in massive tricuspid regurgitation: for a penny, pound! Get access Mariana Martino, Martino Heart Institute, Hospital Universitari Germans Trias i Pujol, Badalona, SpainDepartamento de Cardiología, Clínicas, Universidad la República, Montevideo, Uruguay Search other works by this author on: Oxford Academic PubMed Google Scholar Cristina Conte, Conte SpainDepartment of Cardiovascular and Thoracic Sciences, Catholic University Sacred...
Abstract Background The staging algorithm recently proposed to risk stratify patients with severe aortic stenosis (AS) has not been largely applied who are asymptomatic. While the presence of tricuspid regurgitation, pulmonary hypertension and right ventricular dysfunction (stages 3-4) is expected be low, prevalence left damage (LV), mitral atrial (LA) dilation fibrillation 1-2) can higher in asymptomatic AS. cardiac magnetic resonance (CMR) correlates have described. Purpose To investigate...
Journal Article Corrected proof Atrial functional mitral regurgitation: the tip of iceberg Get access Cristina Conte, Conte Department Cardiovascular Imaging, Heart Institute, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet, s/n, Badalona, Barcelona 08916, SpainDepartment and Thoracic Sciences, Catholic University Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy https://orcid.org/0000-0002-1780-1803 Search for other works by this author on:...
Abstract Background and objectives Low-flow low-gradient (LFLG) aortic stenosis portends bad prognosis in different series. The objective of this study was to evaluate the evolution entity our country. Methods We included 1394 consecutive patients evaluated between 2008-2016 with severe AS (AVA &lt;1 cm²) ejection fraction&gt; 50% from 14 Spanish centres. results (aortic valve intervention mortality) were compared using Kaplan-Meier survival analysis. Results Three groups based on...