Hellen Abreu

ORCID: 0000-0002-1796-1284
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Research Areas
  • Polysaccharides and Plant Cell Walls
  • Fungal Biology and Applications
  • SARS-CoV-2 detection and testing
  • Respiratory viral infections research
  • Phytochemicals and Antioxidant Activities
  • Botanical Research and Applications
  • Seaweed-derived Bioactive Compounds
  • SARS-CoV-2 and COVID-19 Research
  • Essential Oils and Antimicrobial Activity
  • Food composition and properties
  • COVID-19 Clinical Research Studies
  • Infectious Encephalopathies and Encephalitis
  • Bee Products Chemical Analysis
  • Plant Pathogens and Fungal Diseases
  • Advanced biosensing and bioanalysis techniques
  • Phytochemistry Medicinal Plant Applications
  • Phytochemistry and Biological Activities
  • Gut microbiota and health
  • Agricultural and Food Sciences
  • Bacteriophages and microbial interactions
  • Polysaccharides Composition and Applications

Universidade Federal do Paraná
2018-2024

A polysaccharide-enriched extract obtained from Lentinula edodes was submitted to several purification steps separate three different D-glucans with β-(1→6), β-(1→3),(1→6) and α-(1→3) linkages, being characterized through GC-MS, FT-IR, NMR, SEC colorimetric/fluorimetric determinations. Moreover, in vitro hypocholesterolemic, antitumoral, anti-inflammatory antioxidant activities were also tested. Isolated glucans exerted HMGCR inhibitory activity, but only β-(1→6) fractions showed DPPH...

10.1016/j.carbpol.2019.115521 article EN publisher-specific-oa Carbohydrate Polymers 2019-10-24

A β-D-glucan was obtained from the edible mushroom Pholiota nameko by hot aqueous extraction and purification. NMR methylation analyses of purified fraction (GHW-PN, 1.46% yield) indicated presence a (1 → 3)-linked β-D-glucan, highly substituted (~27%) at O-6 single units β-D-Glcp or 6)-β-D-Glcp fragments. The β-glucan (at 0.5, 1, 2%) showed shear thinning behavior when concentration solution increased, there an increase in apparent viscosity. presented gel-like thermal stability under...

10.1016/j.ijbiomac.2018.09.062 article EN publisher-specific-oa International Journal of Biological Macromolecules 2018-09-13

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10.2139/ssrn.4790466 preprint EN 2024-01-01

After the Coronavirus pandemic, importance of virus surveillance was highlighted, reinforcing constant necessity discussing and updating methods for collection diagnoses, including other respiratory viruses. Although nasopharyngeal swab is gold-standard sample detecting genotyping SARS-CoV-2 Influenza viruses, its uncomfortable requires specialized teams, which can be costly. During non-invasive saliva samples proved to a suitable alternative diagnosis, but use this source not recognized...

10.3390/v15122352 article EN cc-by Viruses 2023-11-30

Introduction:The Human Influenza Virus (IFV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) are both etiologic agents for upper diseases can be lethal.Both evolve spread rapidly, being an outbreak risk, like global H1N1 2009 COVID19 pandemics.Samples of nasopharyngeal secretion (NS), followed by RT-PCR, is the gold standard detection method.However, saliva could alternative sampling, more attractive since painless easy to collect, mainly in children. Objectives:The aim this...

10.35259/isi.2023_58004 article EN 2023-01-01
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