A5027315409- Knee injuries and reconstruction techniques
- Additive Manufacturing and 3D Printing Technologies
- Silk-based biomaterials and applications
- Osteoarthritis Treatment and Mechanisms
- 3D Printing in Biomedical Research
- Innovative Microfluidic and Catalytic Techniques Innovation
University of California, Berkeley
2018-2022
Hydrogels are useful materials as scaffolds for tissue engineering applications. Using hydrogels with additive manufacturing techniques has typically required the addition of such cross-linking or printing in sacrificial that negatively impact growth to remedy inconsistencies print fidelity. Thus, there is a need bioinks can directly cell-laden constructs. In this study, agarose-based commonly used cartilage were compared Pluronic, hydrogel established capabilities. Moreover, new material...
Extracellular-matrix composition impacts mechanical performance in native and engineered tissues. Previous studies showed collagen type I-agarose blends increased cell-matrix interactions extracellular matrix production. However, long-term on protein production properties of cartilage are unknown. Our objective was to characterize the effect I chondrocytes embedded agarose hydrogels. We hypothesized that addition would improve (e.g. glycosaminoglycans) through bioactivity. Agarose hydrogels...