A5030996349- Retinal and Optic Conditions
- Nerve injury and regeneration
- Retinal and Macular Surgery
- Glaucoma and retinal disorders
- Alzheimer's disease research and treatments
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cellular transport and secretion
- Microtubule and mitosis dynamics
- Retinal Imaging and Analysis
- 3D Printing in Biomedical Research
- Endoplasmic Reticulum Stress and Disease
- Additive Manufacturing and 3D Printing Technologies
- Bone Tissue Engineering Materials
- Osteoarthritis Treatment and Mechanisms
- Neuropeptides and Animal Physiology
- Vasculitis and related conditions
- Knee injuries and reconstruction techniques
- Innovative Microfluidic and Catalytic Techniques Innovation
- Signaling Pathways in Disease
- Nuclear Receptors and Signaling
- Ocular Oncology and Treatments
- Retinal Diseases and Treatments
- Ocular Diseases and Behçet’s Syndrome
California Retina Consultants
2020-2022
Stanford University
2012-2020
University of California, Berkeley
2017-2018
Hydrogels are useful materials as scaffolds for tissue engineering applications. Using hydrogels with additive manufacturing techniques has typically required the addition of such cross-linking or printing in sacrificial that negatively impact growth to remedy inconsistencies print fidelity. Thus, there is a need bioinks can directly cell-laden constructs. In this study, agarose-based commonly used cartilage were compared Pluronic, hydrogel established capabilities. Moreover, new material...
Neurotrophin (NT) receptors are coupled to numerous signaling networks that play critical roles in neuronal survival and plasticity. Several non-peptide small molecule ligands have recently been reported bind activate specific tropomyosin-receptor kinase (Trk) NT receptors, stimulate their downstream signaling, cause biologic effects similar to, though not completely overlapping, those of the native ligands. Here, silico screening, with low-throughput identified a compound, LM22B-10, that,...
Longitudinal preclinical and clinical studies suggest that Aβ drives neurite synapse degeneration through an array of tau-dependent independent mechanisms. The intracellular signaling networks regulated by the p75 neurotrophin receptor (p75NTR) substantially overlap with those linked to tau. Here we examine hypothesis modulation p75NTR will suppress generation multiple potentially pathogenic tau species related protect dendritic spines processes from Aβ-induced injury. In neurons exposed...
In neurons, a highly regulated microtubule cytoskeleton is essential for many cellular functions. These include axonal transport, regional specialization and synaptic function. Given the critical roles of microtubule-associated proteins (MAPs) in maintaining regulating stability dynamics, we sought to understand how this regulation achieved. Here, identify novel LisH/WD40 repeat protein, tentatively named nemitin (neuronal enriched MAP interacting protein), as potential regulator...
This case report discusses an atypical of cytomegalovirus (CMV) retinal necrosis with panretinal occlusive vasculopathy in a 77-year-old man who was immunosuppressed following treatment for giant cell arteritis (GCA).A is presented.Clinical examination demonstrated central artery occlusion and pale disc suspicious arteritic ischemic optic neuropathy the right eye. Biopsy-proven GCA prompted oral prednisone. While on glucocorticoid immunosuppression, patient suffered vision loss left eye from...
The purpose of this study was to report the findings a hyperreflective nodular epiretinal gliosis observed with optical coherence tomography presumed be due subclinical hyaloidal traction causing Mϋller cell cone gliosis.Retrospective, observational case series.Six eyes six patients (mean age: 57 years, range 35-81 years) presented and had an average follow-up interval 26 months (range 1-82 months). mean baseline best-corrected visual acuity 0.25 ± 0.17 (Snellen equivalent 20/38.3 16.9)....