A5102364641- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Ophthalmology and Visual Impairment Studies
- Retinal and Optic Conditions
- Corneal Surgery and Treatments
- Optical Coherence Tomography Applications
- Ocular Surface and Contact Lens
- Retinal Development and Disorders
- Gut microbiota and health
- Visual perception and processing mechanisms
- Retinal and Macular Surgery
- Probiotics and Fermented Foods
- Diet and metabolism studies
- Microbial Natural Products and Biosynthesis
- Carbohydrate Chemistry and Synthesis
- Microbial Metabolic Engineering and Bioproduction
- interferon and immune responses
- Computer Graphics and Visualization Techniques
- Cultural Differences and Values
- Allelopathy and phytotoxic interactions
- Surgical Simulation and Training
- Human Motion and Animation
- Elevator Systems and Control
Jinzhou Medical University
2024
Jiangsu University of Science and Technology
2024
Tianjin University
2018-2023
Shanghai Institute of Technology
2022
Doheny Eye Institute
2016-2021
Foshan University
2021
Shanxi Agricultural University
2020
Sunnybrook Health Science Centre
2020
Health Sciences Centre
2020
University of Toronto
2020
Growth rate and nutrient availability are the primary determinants of size in single-celled organisms: rapidly growing Escherichia coli cells more than twice as large their slow counterparts. Here we report identification glucosyltransferase OpgH a nutrient-dependent regulator E. cell size. During growth under nutrient-rich conditions, localizes to nascent septal site, where it antagonizes assembly tubulin-like division protein FtsZ, delaying increasing Biochemical analysis is consistent...
The repeatability and reproducibility of quantitative metrics from optical coherence tomographic angiography (OCTA) must be assessed before these data can confidently interpreted in clinical research practice.To evaluate the OCTA-derived retinal vascular metrics.In this cross-sectional study, 21 healthy volunteers (42 eyes) 22 patients with disease (22 eyes), including 14 age-related macular degeneration, 3 epiretinal membrane, 2 diabetic retinopathy, myopic 1 vein occlusion, were enrolled....
The purpose of this study was to evaluate the correlation between quantity intraretinal hyperreflective foci (HRF) in eye with intermediate AMD and progression late AMD.Volume optical coherence tomography (OCT) scans from 114 eyes patients were retrospectively reviewed. HRF assessed both qualitatively quantitatively. Five sequential en face slabs midretina thresholded isolate HRF. These five recombined, area measured whole 6 × 6-mm image (HRFTOT) within central 3-mm (HRF3mm) 5-mm (HRF5mm)...
Aims To evaluate the choriocapillaris (CC) flow alterations around geographic atrophy (GA) in eyes with dry age-related macular degeneration. Methods Using a swept-source optical coherence tomography angiography (SS-OCTA) device, two volume 6×6 mm scans were acquired patients GA presenting between June and December 2017 at Doheny-UCLA Eye Centers. The area of was delineated on en face structural OCT fundus images. For each eye, OCTA slabs level CC from acquisitions averaged compensated for...
PurposeTo identify baseline risk factors for macular atrophy (MA) development in HARBOR via a longitudinal assessment of monthly spectral-domain (SD)-OCT scans. Previous analyses MA examined data from color fundus photography (CFP) and fluorescein angiography (FA).DesignRetrospective, post hoc analysis SD-OCT images (ClinicalTrials.gov identifier, NCT00891735), phase 3, multicenter, prospective, randomized, double-blind, active treatment–controlled clinical trial.ParticipantsPatients (N =...
Abstract Ligninolytic bacteria degrading lignin were isolates and identified, their biodegradation mechanism of alkaline-lignin was investigated. Four strains with degradation capability screened identified from the soil, straw, silage based on decolorizing capacity aniline blue colony size medium. The ratio Bacillus aryabhattai BY5, Acinetobacter johnsonii LN2, lwoffii LN4, Micrococcus yunnanensis CL32 have been assayed using as unique carbon source. Further, Lip (lignin peroxidase) Mnp...
Stern flaps and interceptors are prevalent stern appendages on medium- to high-speed ships, designed modify the sailing posture of ships diminish resistance. Using Reynolds-averaged Navier–Stokes (RANS) method combined with overset mesh technology, this study evaluates performance a ship in regular waves before after interceptor flap installation. The findings indicate that resistance reduction rates initially declined then rose wavelength, typically 1–3% higher than calm water. For constant...
Background/aims To systematically compare the intermodality and inter-reader agreement for two blue-light confocal fundus autofluorescence (FAF) systems. Methods Thirty eyes (21 patients) with a diagnosis of geographic atrophy (GA) were enrolled. Eyes imaged using FAF devices: (1) Spectralis device 488 nm excitation wavelength (488-FAF); (2) EIDON 450 capability ‘colour’ imaging including both individual red green components emission spectrum. Furthermore, third modality (450-RF image)...
To determine the number of just-noticeable differences in wavefront blur necessary to induce a 1-line loss corrected distance visual acuity (CDVA).Visual Optics Institute, College Optometry, University Houston, Texas, USA.Evidence-based manuscript.The 3.0 mm error well-corrected average eye was scaled yield 9 small steps quantified units log Strehl (logVS). For each logVS value, 10 unique 3-line charts were generated. Using temporal forced-choice paradigm, subjects compared test chart...
To quantify on-eye rotational and translational stability of three scleral contact lens stabilization methods to model the variation in visual acuity when these movements occur a wavefront-guided correction for highly aberrated eyes.Three were integrated into posterior periphery designed at Visual Optics Institute. For comparison, with no method (rotationally symmetric periphery) was designed. The lenses manufactured quantified on 8 eyes as average SD observed translations rotations over 60...
Summary Relationship between intestinal flora and obesity has aroused great interest. The probiotic effects of Lactobacillus plantarum ( LP ) fermentum LF have been documented extensively. This study aimed to explore the alone or in combination on lipid‐lowering high‐fat diet rat via modulation systemic immunity. rats plus 10 8 cfu day −1 showed significantly lower IL ‐6 endotoxin ET content, increased number Bifidobacterium decreased liver steatosis fat vehicle sizes. can regulate immune...
This study tested whether congruency between approach/avoidance dispositional motivation and message framing (gain, loss) affects receptivity to appeals for charitable donations. Participants read gain-framed loss-framed messages regarding funding needs completed the BIS vs. BAS scale assessing motivation. Approach-oriented people were more persuaded by messages, avoidance-oriented messages. The results thus extend effect beyond self-relevant include other-oriented as well. These findings...
Purpose: To characterize and correlate guttata severity, Descemet's membrane thickness (DMT), central cornea (CCT) in corneas with guttae using specular microscopy spectral-domain optical coherence tomography (SD-OCT) test the Doheny Image Reading Center (DIRC) microscopy-based corneal severity scale. Methods: Forty-nine eyes of 49 patients 36 age-matched normal controls were enrolled study. Three images four peripheral (inferior, superior, nasal temporal) each eye taken Konan NSP-9900...
Abstract Developing a high-resolution non-invasive optical coherence tomography angiography (OCTA) method for iris vasculature imaging is essential diagnosing wide range of ocular pathologies. However, the current iris-OCTA devices are still limited in quality and penetration depth dark-colored eyes ranging from brown to dark brown. A spectral domain system presented this paper incorporating 1300 nm wavelength deeper tissue penetration, linear-wavenumber spectrometer better detection...
To evaluate the protective effects of microencapsulation on Lactobacillus delbrueckii by random, parallel experimental design.Lincomycin hydrochloride-induced intestinal malfunction mouse model was successfully established; then L. microcapsule given to mouse. The clinical behaviour, number flora, mucous IgA content in small intestine, IgG and IL-2 level peripheral blood were monitored. histological sections also prepared.The could have more probiotic as indicated higher bifidobacterium...
A chemical investigation of a Chinese Pseudomonas aurantiaca strain has yielded new benzoquinone (4) and furanone (5), in addition to the known dialkylresorcinols 1 2. Extensive decomposition studies on major metabolite produced an additional derivative (6), hydroxyquinone (7), two unusual resorcinol dimers (8 9). Structures were elucidated by nuclear magnetic resonance spectroscopy combination with tandem mass spectrometry analysis. These illustrate potential artifacts as source diversity....
Purpose: To quantitatively evaluate the inter-annotator variability of clinicians tracing contours anatomical layers iridocorneal angle on digital gonio photographs, thus providing a baseline for validation automated analysis algorithms. Methods: Using software annotation tool common set 20 images, five experienced ophthalmologists highlighted interest: iris root (IR), ciliary body band (CBB), scleral spur (SS), trabecular meshwork (TM), and cornea (C). Inter-annotator was assessed by (1)...
To demonstrate the effect of averaging multiple en face optical coherence tomography angiography images on correlation between retinal microvasculature quantitative metrics and best-corrected visual acuity (BCVA) in eyes with vein occlusion.A cross-sectional cohort unilateral occlusion was imaged both eyes. Five 3 mm × 3-mm spectral domain were averaged, parameters from averaged versus single correlated logMAR BCVA. Regression analyses performed to correlate BCVA.Ten patients (5 male,...