A5010725236- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- Plant Reproductive Biology
- Salivary Gland Disorders and Functions
- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Optical Imaging and Spectroscopy Techniques
- Postharvest Quality and Shelf Life Management
- Plant responses to water stress
- Plant Gene Expression Analysis
- Retinal Development and Disorders
- Tea Polyphenols and Effects
- Infrared Thermography in Medicine
- Proteoglycans and glycosaminoglycans research
- Hydrogels: synthesis, properties, applications
- Ocular Diseases and Behçet’s Syndrome
- Mitochondrial Function and Pathology
- Light effects on plants
- Bone Tissue Engineering Materials
- Ion Transport and Channel Regulation
Chinese Academy of Agricultural Sciences
2022-2025
Tea Research Institute
2022-2025
Ministry of Agriculture and Rural Affairs
2022-2025
Jinan University
2010-2023
Anhui University
2022
Salk Institute for Biological Studies
2018-2020
Howard Hughes Medical Institute
2018-2020
Doheny Eye Institute
2011-2019
University of California, Los Angeles
2017-2019
Olive View-UCLA Medical Center
2017
Conquering Rice Sterility The hybrid sterility occurring among rice species has long been a puzzle and hampers progress in breeding crops with improved performance yield characteristics. Yang et al. (p. 1336 ) have identified three linked genes encoding killer, partner, protector protein. killer partner work together to kill female gametes not carrying the functional protector, resulting preferential transmission of which also causes segregation distortion progeny. This explanation for how...
The dynamic and specific transcriptome for high light (HL) stress in plants is poorly understood because heat has confounded previous studies. Here, we perform an in-depth temporal responsive analysis identify the core HL-responsive genes. By eliminating effect of heat, uncover a set genes specifically regulated by high-intensity light-driven signaling. We find that 79% restore their expression to baseline within 14-h recovery period. Our study reveals respond HL through regulation hormones,...
The branching angle of tea plants is a key factor in determining their structure, which significantly affects yield, suitability for mechanical harvesting, and overall plant architecture. However, the mechanisms underlying formation remain unclear. In this study, we explored mechanism by analysing transcriptome hormone levels cultivars with different angles. results indicated that gibberellin positively regulates plants, cytokinins, auxin, abscisic acid involved angles plants. analysis...
Background The B-box (BBX) -containing proteins are a class of zinc finger that contain one or two domains and play important roles in plant growth development. Arabidopsis BBX gene family has recently been re-identified renamed. However, there not genome-wide survey the rice (OsBBX) until now. Methodology/Principal Findings In this study, we identified 30 genes through comprehensive bioinformatics analysis. Each was assigned uniform nomenclature. We described chromosome localizations,...
The ethylene response factor (ERF) transcription factors are integral components of environmental stress signaling cascades, regulating a wide variety downstream genes related to responses and plant development. However, the mechanisms by which ERF regulate heat not well understood. Here, we uncover positive role signaling, ERF95 ERF97 in basal thermotolerance Arabidopsis thaliana. We demonstrate that signaling-defective mutants exhibit compromised thermotolerance, whereas plants with...
During development or under stress, chloroplasts generate signals that regulate the expression of a large number nuclear genes, process called retrograde signaling. GENOMES UNCOUPLED 1 (GUN1) is an important regulator this pathway. In study, we have discovered unexpected role for GUN1 in plastid RNA editing, as gun1 mutations affect RNA-editing efficiency at multiple sites plastids during plays direct editing by physically interacting with MULTIPLE ORGANELLAR EDITING FACTOR 2 (MORF2). MORF2...
Abstract Iron (Fe) is essential for life, but in excess can cause oxidative cytotoxicity through the generation of Fe-catalyzed reactive oxygen species. It yet unknown which genes and mechanisms provide Fe-toxicity tolerance. Here, we identify S-nitrosoglutathione-reductase ( GSNOR ) variants underlying a major quantitative locus root tolerance to Arabidopsis using genome-wide association studies allelic complementation. These act largely transcript level regulation. We further show that...
Aspartic proteases (APs) comprise a large proteolytic enzyme family widely distributed in animals, microbes, viruses, and plants. The rice genome encodes 96 APs, of which only few have been functionally characterized. Here, the identification characterization novel AP gene, OsAP65, plays an indispensable role pollen tube growth rice, is reported. T-DNA insertion line OsAP65 caused severe segregation distortion. In progeny derived from individual heterozygous for insertion, wild type...
Peptide transporter (PTR) family whose member can transport di-/tripeptides and nitrate is important for plant growth development. Although the rice (Oryza sativa L.) genome has been sequenced a few years, genomic survey, characterization expression profile analysis of PTR in this species not reported. In study, we report comprehensive identification, characterization, phylogenetic evolutionary 84 members (OsPTR) as well their whole-life patterns. Chromosomal distribution sequence indicate...
Cold stress is a major environmental factor that adversely affects the growth and productivity of tea plants. Upon cold stress, plants accumulate multiple metabolites, including ascorbic acid. However, role acid in response not well understood. Here, we report exogenous treatment improves tolerance We show reduces lipid peroxidation increases Fv/Fm under stress. Transcriptome analysis indicates down-regulates expression biosynthesis genes ROS-scavenging-related genes, while modulating cell...
The corneal epithelium is directly affected in dry eye syndrome. Thus, we attempted to describe the morphological features and evaluate cellular density within epithelial layers patients with non-Sjögren's (NSDE) Sjögren's syndrome eyes (SSDE) by vivo confocal microscopy (IVCM).Central cornea was prospectively imaged IVCM 68 clinically diagnosed aqueous tear-deficient 10 healthy age-matched control eyes. Morphological characteristics of densities were evaluated four trained graders from...
Chloroplast development and function relies on the coordinated regulation of chloroplast nuclear gene expression. Generally, nucleus is in charge; however, chloroplasts also can signal back to via retrograde signaling pathways ([Koussevitzky et al., 2007][1]; [Woodson Chory,
Tea plants (Camellia sinensis) show discrepancies in selenium accumulation and transportation, the molecular mechanisms of which are not well understood. Hence, we aimed to conduct a systematic investigation transportation different tea cultivars via transcriptome analysis. The Na2SeO3 Na2SeO4 treatments improved contents roots leaves three cultivars. high selenium-enrichment ability (HSe) accumulated higher than did low (LSe) Transcriptome analysis revealed that differentially expressed...
To compare endothelial cell analysis obtained by noncontact specular and confocal microscopy, using the Konan NSP-9900 Nidek ConfoScan4 systems, respectively.Three groups including 70 healthy eyes, 49 eyes with Fuchs corneal dystrophy (FECD), 78 glaucoma were examined both microscope ConfocScan4 microscope. Certified graders at Doheny Image Reading Center compared images from instruments side to assess image quality. Endothelial density (ECD) measurements calculated three different...
To determine the reliability of corneal endothelial cell density (ECD) obtained by automated specular microscopy versus that validated manual methods and factors predict such reliability.Sharp central images from 94 control 106 glaucomatous eyes were captured with Konan microscope NSP-9900. All analyzed trained graders using CellChek Software, employing fully- semi-automated as well Center Method. Images low count (input cells number <100) and/or guttata compared Flex-Center Methods. ECDs...