Baohai Li

ORCID: 0000-0002-9905-5890
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About
Contact & Profiles
Research Areas
  • Plant nutrient uptake and metabolism
  • Plant Stress Responses and Tolerance
  • Plant responses to water stress
  • Plant Molecular Biology Research
  • Genomics and Phylogenetic Studies
  • Identification and Quantification in Food
  • Plant Micronutrient Interactions and Effects
  • Fish Biology and Ecology Studies
  • Regulation of Appetite and Obesity
  • Neurobiology and Insect Physiology Research
  • Aluminum toxicity and tolerance in plants and animals
  • Plant Reproductive Biology
  • Polysaccharides and Plant Cell Walls
  • Biochemical Analysis and Sensing Techniques
  • Plant Growth Enhancement Techniques
  • Photosynthetic Processes and Mechanisms
  • RNA Research and Splicing
  • Aquaculture disease management and microbiota
  • Neuropeptides and Animal Physiology
  • Cancer-related molecular mechanisms research
  • Connexins and lens biology
  • Light effects on plants
  • E-commerce and Technology Innovations
  • Advanced Technologies in Various Fields
  • Seedling growth and survival studies

Zhejiang University
2019-2024

Salk Institute for Biological Studies
2019-2024

The University of Tokyo
2017-2022

305 Hospital of People Liberation Army
2020

Gregor Mendel Institute of Molecular Plant Biology
2019

Austrian Academy of Sciences
2019

Vienna Biocenter
2019

Tibet Academy of Agricultural and Animal Husbandry Sciences
2016-2019

Institute of Soil Science
2010-2015

Chinese Academy of Sciences
2010-2015

<h3>Importance</h3> The gastric cancer (GC)–associated long noncoding RNA1 (lncRNA-GC1) plays an important role in carcinogenesis. However, exosomal lncRNA-GC1 and its potential GC are poorly understood. <h3>Objective</h3> To evaluate the diagnostic value of circulating for early detection monitoring progression GC. <h3>Design, Setting, Participants</h3> We performed a multiphase investigation involving consecutive patients with (n = 522), precancerous lesions 85), healthy donor individuals...

10.1001/jamasurg.2020.1133 article EN cc-by JAMA Surgery 2020-06-10

Ammonium (NH4+) is a ubiquitous intermediate of nitrogen metabolism but notorious for its toxic effects on most organisms. Extensive studies the underlying mechanisms NH4+ toxicity have been reported in plants, it poorly understood how plants acclimate to high levels NH4+. Here, we identified an Arabidopsis (Arabidopsis thaliana) mutant, ammonium overly sensitive1 (amos1), that displays severe chlorosis under stress. Map-based cloning shows amos1 carry mutation EGY1 (for ethylene-dependent,...

10.1104/pp.112.206508 article EN PLANT PHYSIOLOGY 2012-10-12

Abstract Iron (Fe) is essential for life, but in excess can cause oxidative cytotoxicity through the generation of Fe-catalyzed reactive oxygen species. It yet unknown which genes and mechanisms provide Fe-toxicity tolerance. Here, we identify S-nitrosoglutathione-reductase ( GSNOR ) variants underlying a major quantitative locus root tolerance to Arabidopsis using genome-wide association studies allelic complementation. These act largely transcript level regulation. We further show that...

10.1038/s41467-019-11892-5 article EN cc-by Nature Communications 2019-08-29

The lignocellulosic biorefinery industry can be an important contributor to achieving global carbon net zero goals. However, low valorization of the waste lignin severely limits sustainability biorefineries. Using a hydrothermal reaction, we have converted sulfuric acid (SAL) into water-soluble SAL (HSAL). Here, show improvement HSAL on plant nutrient bioavailability and growth through its metal chelating capacity. We characterize HSAL's high ratio phenolic hydroxyl groups methoxy capacity...

10.1038/s41467-023-40497-2 article EN cc-by Nature Communications 2023-08-11

ABSTRACT Deposition of ammonium (NH 4 + ) from the atmosphere is a substantial environmental problem. While toxicity resulting root exposure to NH well studied, little known about how shoot‐supplied (SSA) affects growth. In this study, we show that SSA significantly lateral (LR) development. We inhibits primordium (LRP) emergence, but not LRP initiation, in impaired LR number. inhibition independent abscisic acid (ABA) signalling and sucrose uptake shoots relates auxin response roots....

10.1111/j.1365-3040.2011.02295.x article EN Plant Cell & Environment 2011-02-23

Root gravitropism is affected by many environmental stresses, including salinity, drought, and nutrient deficiency. One significant stress, excess ammonium (NH4+), well documented to inhibit root elongation lateral formation, yet little known about its effects on the direction of growth. We show here that inhibition upon elevation external NH4+ accompanied a loss in (agravitropism) Arabidopsis. Addition potassium (K+) treatment medium partially rescued high but did not improve gravitropic...

10.1093/jxb/ers068 article EN Journal of Experimental Botany 2012-03-09

A stunted root system is a significant symptom of iron (Fe) toxicity, yet little known about the effects excess Fe on lateral (LR) development. In this work, we show that has different LR development in portions Arabidopsis (Arabidopsis thaliana) and inhibitory initiation are only seen roots newly formed during exposure. We tip contact with both necessary sufficient for inhibition auxin, but not abscisic acid, pathway engaged centrally initial stages Furthermore, stress significantly reduced...

10.1104/pp.15.00904 article EN PLANT PHYSIOLOGY 2015-10-14

Foliar NH4+ exposure is linked to inhibition of lateral root (LR) formation. Here, the role shoot ethylene in NH4+-induced LR formation Arabidopsis was investigated using wild-type and mutant lines that show either blocked signalling (etr1) or enhanced synthesis (eto1, xbat32). led pronounced production chiefly distal root, triggered evolution activity reporter EBS:GUS shoot. It shown contact with necessary stimulate evolution. The antagonists Ag+ aminoethoxyvinylglycine (AVG) mitigated...

10.1093/jxb/ert019 article EN Journal of Experimental Botany 2013-02-04

Abstract Zinc (Zn) is an essential micronutrient but can be cytotoxic when present in excess. Plants have evolved mechanisms to tolerate Zn toxicity. To identify genetic loci responsible for natural variation of plant tolerance toxicity, we conduct genome-wide association studies root growth responses high and 21 significant associated loci. Among these loci, Trichome Birefringence ( TBR ) allelic determining conditions. Natural alleles determine transcript protein levels which affect pectin...

10.1038/s41467-024-50106-5 article EN cc-by Nature Communications 2024-07-11

Summary Gravitropism plays a critical role in plant growth and development, stability acclimation to changes water nutrient availability. Ammonium (NH 4 + ) is well known have profound effects on root growth, but its impacts gravitropism are poorly understood. To determine which genes essential for the maintenance of under NH stress, we isolated identified an ‐sensitive mutant, gsa‐1 ( g ravitropism s ensitive mmonium‐ 1 ), Arabidopsis thaliana , using agar plate reorientation assay. We...

10.1111/nph.12365 article EN New Phytologist 2013-06-20

Efficient uptake of nutrients in both animal and plant cells requires tissue-spanning diffusion barriers separating inner tissues from the outer lumen/soil. However, we poorly understand how such contiguous three-dimensional superstructures are formed plants. Here, show that correct establishment Casparian Strip (CS) network relies on local neighbor communication. We positioning membrane domains (CSDs) is tightly coordinated between neighbors wild-type restriction domain formation involves...

10.7554/elife.69602 article EN cc-by eLife 2022-01-14

Abstract Ammonium (NH4+) is toxic to root growth in most plants already at moderate levels of supply, but mechanisms tolerance NH4+ remain poorly understood. Here, we report that high induce nitric oxide (NO) accumulation, while inhibiting potassium (K+) acquisition via SNO1 (sensitive 1)/SOS4 (salt overly sensitive 4), leading the arrest primary growth. High also stimulated accumulation GSNOR (S-nitrosoglutathione reductase) roots. overexpression improved NH4+. Loss further induced NO...

10.1093/jxb/erab140 article EN Journal of Experimental Botany 2021-03-24

Despite the importance of preventing calcium (Ca) deficiency disorders in agriculture, knowledge molecular mechanisms underlying plant adaptations to low-Ca conditions is limited. In this study, we provide evidence for a crucial involvement callose synthesis survival Arabidopsis (Arabidopsis thaliana) under conditions. A mutant sensitive conditions, low sensitive3 (lcs3), exhibited high levels cell death emerging leaves and had defects its expanding true Further analyses showed that causal...

10.1104/pp.19.00784 article EN PLANT PHYSIOLOGY 2020-02-05

Summary Increased planting densities boost crop yields. A compact plant architecture facilitates dense planting. However, the mechanisms regulating in cucurbits remain unclear. In this study, we identified a cucumber ( Cucumis sativus ) cpa1 mutant from an ethyl methane sulfonate (EMS)‐mutagenized library that exhibited distinctive phenotypic traits, including reduced leaf petiole angle and size. The candidate mutation causes premature stop codon CsaV3_1G036420 , which shares similarity to...

10.1111/pbi.14298 article EN cc-by-nc-nd Plant Biotechnology Journal 2024-01-23
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