A5038466176- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Retinal and Macular Surgery
- Ocular Oncology and Treatments
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Corneal Surgery and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Nonmelanoma Skin Cancer Studies
- Neurogenesis and neuroplasticity mechanisms
- Ocular Infections and Treatments
- Axon Guidance and Neuronal Signaling
- Cutaneous Melanoma Detection and Management
- Vascular Malformations Diagnosis and Treatment
- Retinal Development and Disorders
- Cerebral Venous Sinus Thrombosis
- Drug-Induced Ocular Toxicity
- Glioma Diagnosis and Treatment
- Advanced Fluorescence Microscopy Techniques
- Corneal surgery and disorders
- Retinoids in leukemia and cellular processes
- Intraoperative Neuromonitoring and Anesthetic Effects
- Neuroscience and Neuropharmacology Research
- Intracranial Aneurysms: Treatment and Complications
Retina Vitreous Associates of Florida
2020-2023
SUNY Upstate Medical University
2019-2022
Massachusetts Eye and Ear Infirmary
2016-2020
Harvard University
2016-2020
Sunnybrook Health Science Centre
2020
Health Sciences Centre
2020
University of Toronto
2020
Duke Medical Center
2015-2016
Duke University
2015-2016
University of Münster
2008-2016
Keratoconus (KC) is a corneal ectasia whose pathophysiology still mostly unknown. We investigated whether thyroid gland dysfunction (TGD) associated with the development of KC.We first conducted an epidemiological study, examining prevalence TGD among patients KC. Then, we compared tear thyroxine (T4) in and immunohistochemical staining its receptors (T4Rs) between KC controls. The significance T4 for metabolism was studied organotypic tissue cultures from monkey corneas.We found that 13.6%,...
Abstract The interactions between migrating glioma cells and myelinated fiber tracts are poorly understood. We identified that C6 can migrate along chicken retinal axons in a novel coculture, thereby expressing small GTPases of the Rho family serine/threonine Rho‐associated kinases (ROCKs). found ROCK1 isoform is also highly expressed native human high‐grade gliomas. Glioma migrated faster vitro than on laminin‐1, with former but not latter being specifically reversibly blocked by ROCK...
Sebaceous carcinoma is a rare cutaneous malignancy that most frequently found in the eyelids with an estimated risk of regional lymph node metastasis 8% to 14% range. The authors have previously reported use sentinel biopsy and microscopically positive nodes various eyelid conjunctival cancers, including melanoma Merkel cell carcinoma. herein describe first successful identification patient sebaceous eyelid, suggesting for deserves further investigation.
Purpose: To evaluate the deeper choroidal vasculature in eyes with various ocular disorders using spectral domain (SD) optical coherence tomography angiography (OCTA) and swept source (SS) OCTA. Methods: Patients underwent OCTA imaging either SD-OCTA (Zeiss Cirrus Angioplex or Optovue AngioVue) SS-OCTA (Topcon Triton). Retinal pigment epithelium (RPE) integrity, structural visualization of deep vessels on en face imaging, blood flow signal were analyzed. Choroidal was deemed present if...
An 83-year-old man presented with a 1-month history of rapidly enlarging conjunctival mass. On examination, slit lamp biomicroscopy revealed leukoplakic tumour at the temporal limbus. The lesion was excised cryotherapy application to limbus and margins. Histopathology keratoacanthoma (KA). KA typically occurs on sun-exposed areas skin. Conjunctival is very rare, differentiation between conventional squamous cell carcinoma (SCCA) can be challenging. present case highlights indication for...
To compare functional and anatomical outcomes complication rates between valved versus traditional nonvalved small-gauge cannula vitrectomy for retinal detachment repair.Retrospective case series of 163 eyes undergoing with intraoperative perfluoro-n-octane repair at a single academic institution.There were 104 in the group 59 group. The had lower baseline Grade C proliferative vitreoretinopathy (35 vs. 53%, P = 0.031) combined rhegmatogenous detachment/tractional (3 12%, 0.037), but both...
Abstract: Perfluorocarbon liquids (PFCL) have transformed the surgical approach to complex retinal detachments, but their use can be complicated by subretinal retention. Migration of peripherally located PFCL towards fovea is well established, spontaneous resolution subfoveal without evacuation or displacement has rarely been described. We present a case large single retained droplet following vitrectomy with membrane peeling, inferior relaxing retinectomy, and silicone oil tamponade that...
Purpose: Valved cannulas are a recent addition to small-gauge pars plana vitrectomy (PPV) and provide stable intraocular fluidics. The goal of this study was compare outcomes postoperative complication rates valved vs nonvalved cannula PPV for repair retinal detachments (RDs) complicated by Grade C proliferative vitreoretinopathy (PVR). Methods: A retrospective chart review 364 consecutive eyes with either or RD performed. primary were single surgery final anatomic success change in...
Isolated superior ophthalmic vein (SOV) thrombosis is a rare condition usually related to inflammation of the orbit or paranasal sinuses. Patients present with acute orbital signs, including proptosis, ophthalmoplegia, globe dystopia, and periorbital edema, may have diminished vision secondary optic neuropathy. SOV typically seen in setting septic cavernous sinus thrombosis, antimicrobial therapy treatment choice. We herein report what be first case isolated hypercoagulability patient cancer...
A hallmark of gliomas is the growth and migration cells over long distances within brain proliferation selected niches, indicating that migrating navigate between complex substrates. We demonstrate in present study a differential preference for depends on Rho-associated coil kinase (ROCK) signaling, using alternating Bonhoeffer stripe assay. Membrane fractions from nonmyelinated myelinated areas female rats, purified myelin also commercial extracellular matrix were used as substrates, with...
To investigate the choroidal thickness (CT) and vascular densities (CVD) of patients with macular telangiectasia type 2 (MacTel2) their association other multimodal imaging features, using swept-source optical coherence tomography (SS-OCT).Prospective, cross-sectional study. Consecutive MacTel2 along controls without any disease were included. Fundus photography, confocal blue reflectance, near-infrared autofluorescence, fluorescein angiography, spectral domain OCT SS-OCT performed. Images...