A5063098150- Palliative Care and End-of-Life Issues
- Patient Dignity and Privacy
- Childhood Cancer Survivors' Quality of Life
- Family and Patient Care in Intensive Care Units
- Geriatric Care and Nursing Homes
- Patient-Provider Communication in Healthcare
- Transplantation: Methods and Outcomes
- Connexins and lens biology
- Cancer survivorship and care
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Neuroscience and Neuropharmacology Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Systems, Economic Evaluations, Quality of Life
- Nicotinic Acetylcholine Receptors Study
- Grief, Bereavement, and Mental Health
- Polyomavirus and related diseases
- Heart Failure Treatment and Management
- Pulmonary Hypertension Research and Treatments
- Organ Donation and Transplantation
- Healthcare Quality and Management
- Clinical practice guidelines implementation
- Respiratory Support and Mechanisms
- Medical and Biological Sciences
- Pharmacological Effects and Toxicity Studies
- Ion channel regulation and function
University Health Network
2015-2024
University of Toronto
2015-2024
Health Net
2020-2023
University of Ottawa
2023
Bruyère
2023
Toronto General Hospital
2013-2021
Princess Margaret Cancer Centre
2011-2020
Women's College Hospital
2020
Sunnybrook Health Science Centre
2015
Health Sciences Centre
2015
To describe current referral practices of oncologists to specialized palliative care (SPC) and define demographic characteristics, practice situations, opinions associated with referral.Physician members the Canadian Association Medical Oncologists, Radiation Society Surgical Oncology were invited participate in an anonymous survey assessing SPC practices. Participants received two e-mailed mailed invitations.The response rate was 72% (603 839 physicians); 37% medical...
Abstract Background Studies have shown that telehealth applications in palliative care are feasible, can improve quality of care, and reduce costs but few studies focused on user acceptance current technology care. Furthermore, the perspectives health administrators not been explored yet they often heavily involved, alongside providers, coordination use technologies. The study aim was to explore both provider administrator perceptions regarding usefulness ease using Methods Technology...
Gap junctions (gjs) are increasingly recognized as playing a significant role in seizures. We demonstrate that different types of gap junctional blocking agents reduce the duration evoked seizure-like primary afterdischarges (PADs) rat vitro CA1 hippocampal pyramidal region, following repetitive tetanization Schaffer collaterals. Intracellular acidosis, which is known to block communication, decreased PADs, whereas alkalinization increased PADs. Cellular excitability was not significantly...
Clinician-patient communication is central in palliative care, but it has not been described qualitatively which specific elements of are important for high-quality particularly the inpatient setting.Our aim was to identify that quality care and satisfaction with on units (PCUs), as by inpatients, family caregivers, health providers.Qualitative interviews patients/caregivers focus groups staff were conducted four PCUs. Semi-structured elicited thoughts about characteristics PCU inpatients...
Abstract Objective Previous studies regarding patients' end of life (EOL) preparation have focused mainly on practical tasks, such as advance directives. In this study, we investigate the relational and personal aspects EOL preparation, using a patient‐completed questionnaire, examine associations with clinician–patient communication (CPC) other variables. Methods Patients advanced cancer but good performance status were recruited from 24 medical oncology clinics, to participate in...
Chronic (18 h) exposure of cultured hippocampal slices to the type-A GABA receptor blocker, bicuculline methiodide (BMI) 10 micro m increased levels connexin 43 (Cx43) and 32 (Cx32) mRNAs, but not 26 36, as demonstrated by RNase protection assays. The Cx43 Cx32 proteins in membrane fractions detected western blotting were also significantly increased. Immunoblotting indicated that BMI promoted a significant expression transcription protein c-fos. rate fluorescence recovery after...
In Brief Gap junctions are protein channels that directly connect the cytosol of neighboring cells, thus forming electrical synapses and promoting synchronous neuronal activities. Such activities lead to initiation propagation electroencephalogram oscillations implicated in cognition consciousness. this study, we investigated effects propofol, thiopental, halothane on gap junction communication cultured organotypic hippocampal slices by recovery fluorescence after photo bleaching (FRAP)...
Palliative care is well suited to support patients hospitalized with COVID-19, but integration into has been variable and generally poor.To understand barriers facilitators of palliative for COVID-19.Internists, Intensivists physicians completed semi-structured interviews about their experiences providing COVID-19. Results were analysed using thematic analysis.Twenty-three (13 specialist care, five intensivists, general internists) interviewed; mean ± SD age was 42 11 years 61% female. Six...
BackgroundPatients with heart failure have palliative care needs that can be effectively addressed by specialist (SPC). Despite this, SPC utilization this patient population is low, suggesting barriers to referral. We sought determine the referral practices of cardiologists SPC.MethodsCardiologists across Canada were invited participate in a survey about their SPC. Associations between and demographic, professional, attitudinal factors analyzed using multiple logistic regression.ResultsThe...
Abstract Although patients within a transplant program are awaiting or have received disease modifying curative treatment, they also facing advanced illness and the possibility of death. The involvement specialized palliative care services for these may improve symptom management facilitate advance planning. However, in organ transplantation programs difficulty accessing resources often do so only sporadically inpatient setting. Currently, there is little access to ambulatory been no...
Evidence supporting early palliative care is based on trials of specialised care, but a more sustainable model might involve mainly primary providers.The aim this study was to compare the characteristics physicians providing and their attitudes towards perception having sufficient resources for its provision.Survey distributed by mail e-mail. Specialised providers were defined as both receiving referrals from other not only own patients.A total 531 in Canada (71% participation) participated...
During the coronavirus disease (COVID-19) global pandemic, urgent strategies to alleviate shortages are required. Evaluation of feasibility, practicality, and value drug conservation therapeutic alternatives requires a collaborative approach at provincial level. The Ontario COVID-19 ICU Drug Task Force was directed create recommendations suggesting for essential drugs risk shortage in intensive care unit during pandemic. Recommendations were rapidly developed using modified Delphi method...