A5029286946- Pharmacological Effects and Assays
- 2D Materials and Applications
- Stress Responses and Cortisol
- Adipose Tissue and Metabolism
- Quantum and electron transport phenomena
- Mindfulness and Compassion Interventions
- Nutrition and Health in Aging
- Marriage and Sexual Relationships
- Meta-analysis and systematic reviews
- Child Nutrition and Feeding Issues
- Pharmaceutical Practices and Patient Outcomes
- Diagnosis and treatment of tuberculosis
- Graphene research and applications
- Perovskite Materials and Applications
- Topological Materials and Phenomena
- Mycobacterium research and diagnosis
- Bone health and treatments
- Tuberculosis Research and Epidemiology
- Cardiovascular and exercise physiology
- Genetics and Physical Performance
- Diet and metabolism studies
- Intensive Care Unit Cognitive Disorders
- Mast cells and histamine
- Sexual function and dysfunction studies
- Clinical Nutrition and Gastroenterology
Northern Sydney Local Health District
2022-2024
The University of Sydney
2021-2024
The University of Texas at Tyler
2024
National Yang Ming Chiao Tung University
2023-2024
Royal North Shore Hospital
2021-2022
Hanoi Medical University
2020
Bạch Mai Hospital
2019
Columbia University
2016
Aging, medication use, and global function are associated with changes in the microbiome. However, their interrelationships over time require further characterization. In a longitudinal aging mouse study, we investigated effects of aging, chronic polypharmacy high Drug Burden Index (DBI, measure total anticholinergic sedative exposure) gradual cessation (deprescribing) on microbiome, exploring any association outcomes. Chronic administration DBI attenuated aging-related reduction alpha...
This work reports molecular beam epitaxy (MBE) of two-dimensional (2D) GaSe on a three-dimensional (3D) GaN/sapphire platform, which is widely recognized as potential candidate for electronics and optoelectronic applications. Herein, we have demonstrated that regulating the adatoms’ mobility via growth temperature can enable mode transition from screw dislocation-driven (SDD) to layer-by-layer (LBL) in 2D-GaSe. Typically, high-density uniform spiral structure observed SDD-GaSe at low...
Abstract Males and females may respond differently to medications, yet knowledge about sexual dimorphisms in the effects of polypharmacy remains limited, particularly aging. This study aimed assess effect high Drug Burden Index (DBI) treatment compared control on physical function behavior young old, male female mice. We studied whether age sex play a role following they are paralleled by differences serum drug levels. Young (2.5 months) old (21.5 months), C57BL/6 mice were randomized or DBI...
Abstract Functional independence is an important aspect of successful aging and differs with age by sex in humans. Physical performance often declines earlier than other age-associated functional impairments. Rodent models are used to study pharmacological/toxicological effects human therapies. However, physical outcomes mice usually assessed for short periods, limited information on the influence sex. Here, we investigated how affected murine over 23 hours continuous observation. Young (3...
Aging, polypharmacy (concurrent use of ≥ 5 medications), and functional impairment are global healthcare challenges. However, knowledge the age/sex-specific effects is limited, particularly on daily physical activities. Using continuous monitoring, we demonstrated how with high Drug Burden Index (DBI-cumulative anticholinergic/sedative exposure) affected behaviors over 23 h in male/female, young/old mice. For comparison, also evaluated different drug regimens (polypharmacy/monotherapy)...
Abstract Background Ageing, sex and polypharmacy affect physical function. Objectives This mouse study investigates how ageing, interact grip strength, balance beam wire hang, correlating comparing the different test results between within subgroups. Methods Young (2.5 months) old (21.5 C57BL/6 J male female mice ( n = 10–6/group) were assessed for function at baseline on hang with three trials of 60 s (WH60s) one trial 300 (WH300s). Mice randomised to control or diet containing a high Drug...
Herein, a tight‐binding description is utilized to investigate electronic structures and density of states single‐layer (SL) bilayer (BL) graphene ribbons with without the influence external electric fields. Analyses are implemented reveal similarity difference among properties three types (specifically SL BL AA AB stackings). Moreover, both armchair zigzag edge orientations considered. It indicated in results that variation these presence fields depends on structural form orientation. The...
A woman was evaluated for a rare endocrine phenomenon characterized by the combination of excessive thyroid hormone production and elevated serum calcium levels, presenting diagnostic challenge due to interplay between these two pathways.
Abstract Background Cnidium monnieri (L.) Cuss. has been used for a long time according to the traditional experiences and documentation in order treat male sexual disorders. Osthole is one of main bioactive components Cuss . In this study, we aimed evaluate effect fruit extract which osthole content was 35% (determined by HPLC method) on behaviors adult rats. Methods administered orally at dose 150 mg/kg b.w after 30 min, rats were coupled with receptive female behaviors, including mounting...
Background/Objective Enteral nutrition (tube feeding) is standard of care for patients who are unable to tolerate oral intake. Although generally regarded as safe, enteral devices can result in complications and death. More evidence needed clarify risks. Body mass index (BMI; kg/m 2 ) a poorly studied risk factor this regard. With the increasing prevalence obesity US, it important better understand relationship BMI risk. In retrospective study electronic medical records, we explored role...