A5040535444- BRCA gene mutations in cancer
- Genetic Associations and Epidemiology
- Breast Cancer Treatment Studies
- Cancer Genomics and Diagnostics
- Cancer Risks and Factors
- NF-κB Signaling Pathways
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatitis C virus research
- Natural product bioactivities and synthesis
- Nuclear Receptors and Signaling
- MicroRNA in disease regulation
- Cytokine Signaling Pathways and Interactions
- Hepatitis B Virus Studies
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- TGF-β signaling in diseases
- Digestive system and related health
- Genomic variations and chromosomal abnormalities
- Blood Coagulation and Thrombosis Mechanisms
- Digital Radiography and Breast Imaging
- Genetic factors in colorectal cancer
- Global Cancer Incidence and Screening
- Nutrition, Genetics, and Disease
- Liver Disease Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
Mashhad University of Medical Sciences
2020-2024
Shiraz University of Medical Sciences
2021
Abstract Purpose Colorectal cancer (CRC) is one of the common cancers with a high mortality rate worldwide. In Iran, there has been trend increased incidence colorectal in last three decades that necessitates early diagnosis. Genetic factors have an influential role its etiology along conventional risk such as age, diet, and lifestyle. Results from GWAS shown significant associations between SMAD7 gene variants CRC. This study aimed to assess association certain polymorphisms well haplotypes...
Aims: Breast cancer (BC) is one of the most common cancers among women. The influence genetic variations on BC risk has been thus far assessed via genome-wide association studies. NF-κB recognized as a major player in progression. In this study, between rs28362491 and was evaluated population from northeastern Iran. Materials & methods: This study conducted 476 patients with 524 healthy controls. genotyping method used an amplification-refractory mutation system. Results: INS/DEL genotype...
Despite suggesting many genetic risk markers as the outcome of Genome-wide association studies (GWAS) for breast cancer, replicating results in different populations has remained main issue. In this regard, study assessed two variations Zinc Finger 365 (ZNF365) an Iranian population.In a case-control conducted at Mashhad University Medical Sciences, Mashhad, Iran, between 2017 and 2020, ZNF365-rs10822013 rs10995190 were genotyped using Allele-Specific PCR (AS-PCR). Breast density was...