- Nanoparticles: synthesis and applications
- Advanced Nanomaterials in Catalysis
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Pancreatic function and diabetes
- Graphene and Nanomaterials Applications
- Cardiac Arrest and Resuscitation
- Immune cells in cancer
- Sepsis Diagnosis and Treatment
- Genetics and Neurodevelopmental Disorders
- Phytochemicals and Antioxidant Activities
- Cellular transport and secretion
- Nitric Oxide and Endothelin Effects
- Heavy Metal Exposure and Toxicity
- Advanced biosensing and bioanalysis techniques
- Flavonoids in Medical Research
- RNA Interference and Gene Delivery
- Eicosanoids and Hypertension Pharmacology
- Respiratory Support and Mechanisms
- Obstructive Sleep Apnea Research
- Pharmacological Effects of Natural Compounds
- Nanoparticle-Based Drug Delivery
Mary Lyon Centre at MRC Harwell
2024
Universidade do Porto
2015-2022
Centro Hospitalar do Porto
2022
Rede de Química e Tecnologia
2015-2020
Royal Brompton & Harefield NHS Foundation Trust
2018
Despite the widespread use of silver nanoparticles (AgNPs) in several daily consumer products, putative human risks resulting from continuous exposure remain elusive, particularly with what concerns reactivity immune system and pro-inflammatory effects. Neutrophils are considered one first primary cell types that process systemic nanoparticles, mediating host inflammatory immunological response, involving production reactive oxygen nitrogen species. The main objective present study was to...
The purpose of an experimental design is to improve the productivity experimentation. It efficient procedure for planning experiments, so data obtained can be analyzed yield a valid and objective conclusion. This approach has been used as important tool in optimization different analytical approaches. A D-optimal was here, first time, optimize conditions detection reactive oxygen species (ROS) produced by human blood from healthy donors, biological matrix that better resembles physiologic...
The vacuolar ATPase (v-ATPase) is essential for acidification of intracellular organelles, including synaptic vesicles. Its activity controlled by cycles association and dissociation the ATP hydrolysis (V
Nurses have an important role in early identification of factors that can compromise oxygen delivery to the lungs and tissues body, ensuring patients who may require supplemental therapy are assessed managed safely competently. This article provides overview anatomy physiology relation outlines common indications contraindications for therapy. It also discusses approaches nurses adopt assess a patient's clinical need therapy, as well safety considerations required.