A5101518603- Chronic Kidney Disease and Diabetes
- Renal Diseases and Glomerulopathies
- Diabetes Treatment and Management
- Dialysis and Renal Disease Management
- Catalytic Processes in Materials Science
- Catalysis and Oxidation Reactions
- Diabetes Management and Research
- Industrial Gas Emission Control
- Energetic Materials and Combustion
- Thermal and Kinetic Analysis
- Organ Donation and Transplantation
- Acute Kidney Injury Research
- Crystallography and molecular interactions
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Platelet Disorders and Treatments
- Systemic Sclerosis and Related Diseases
- Vibration Control and Rheological Fluids
- Muon and positron interactions and applications
- Antibiotics Pharmacokinetics and Efficacy
- Autopsy Techniques and Outcomes
- Renal cell carcinoma treatment
- Urinary Bladder and Prostate Research
- Pancreatic function and diabetes
- Characterization and Applications of Magnetic Nanoparticles
University of Ulster
2012-2025
Belfast City Hospital
2012-2025
Belfast Health and Social Care Trust
2024
University of Oxford
2023
Queen's University Belfast
2004-2013
Royal Victoria Hospital
2013
Cranfield University
1995-1996
Defence Academy of the United Kingdom
1995-1996
Royal Military College of Canada
1996
Massachusetts Institute of Technology
1976
We investigated the prevalence of chronic kidney disease and attainment therapeutic targets for HbA1c blood pressure in a large U.K.-based diabetes population.The U.K. National Diabetes Audit provided data from 1 January 2007 to 31 March 2008. Inclusion criteria were documented urinary albumin:creatinine ratio serum creatinine. Patients stratified according stage albuminuria status. Chronic was defined as an estimated glomerular filtration rate < 60 ml min(-1) 1.73 m(-2) , or both. The...
<sec> <title>BACKGROUND</title> Artificial intelligence (AI) and Large Language models (LLMs) are increasing in sophistication have become integrated into many industries. The potential for LLMs to augment clinical decisions is an evolving area of research. </sec> <title>OBJECTIVE</title> This study compared the responses over 1000 kidney specialist physicians (nephrologists) outputs commonly used using a questionnaire determining when biopsy should be performed. <title>METHODS</title>...
Background: Obesity is increasingly prevalent in many countries. a major risk factor for the development of type 2 diabetes but its relationship with diabetic kidney disease (DKD) remains unclear. Some studies have suggested that metabolic syndrome (including obesity) may be associated DKD 1 diabetes. Aim: To investigate association between obesity and DKD. Design: Retrospective cross-sectional study. Methods: National Diabetes Audit data were available 2007–08 cycle. Type patients both...
Background Kidney biopsy is an important investigation in nephrology and facilitates the diagnosis of many conditions. It invasive procedure with risk significant complications, which limits its usage. There minimal literature on how patients experience a kidney biopsy. Identifying addressing barriers to access may expand opportunities for treatment. We hypothesise that differently, depending each individual’s circumstances. Methods Ten participants, who had undergone total twenty-three...
Key Points Attitudes on kidney biopsy practice vary significantly across the world. Male clinicians, younger and individuals who perform biopsies more frequently had an increased propensity to recommend a biopsy. Kidney was most often recommended in setting of higher proteinuria levels preserved function. Background A is essential investigation for diagnosis but invasive associated with complications. Delaying or missing opportunity diagnose disease could result adverse patient outcomes. The...
Abstract Background: Preclinical evidence suggests that 5α-reductase inhibitors (5ARi), commonly used to treat benign prostatic hyperplasia (BPH), are associated with reduced incidence of certain urologic cancers, yet epidemiologic studies conflicting. This study aimed determine whether 5ARi's a risk kidney and bladder cancers. Methods: We conducted new-user active-comparator cohort in the United Kingdom Clinical Practice Research Datalink. From base patients incident BPH, new users...
Following concerns regarding the emergence of Clostridium difficile infection in 2010, we changed antibiotic prophylaxis patients undergoing primary hip and knee arthroplasty from cefuroxime to flucloxacillin single-dose (SD) gentamicin. A subsequent perceived increase incidence post-operative acute kidney injury (AKI) led us evaluate AKI between different prophylactic regimes used at our centre.We examined as defined by Kidney Disease: Improving Global Outcomes criteria 1588 or January 2010...
Abstract Pre‐clinical evidence suggests that 5‐alpha reductase inhibitors (5ARi's), prescribed in the treatment of benign prostatic hyperplasia, reduce colorectal and gastro‐oesophageal cancer incidence via action on male hormonal pathway. However, few studies to date have investigated this association at population level. Our study aimed investigate risk cancers with use 5ARi's. We conducted a retrospective cohort new users 5ARi's alpha‐blockers among patients hyperplasia UK Clinical...
<title>Abstract</title> <bold>Background</bold> IgA Nephropathy (IgAN) is the most common primary glomerulonephritis in world and a cause of chronic kidney disease (CKD) failure. Outcomes are heterogeneous accurate risk stratification important to identify highest individuals for treatment help prevent progression. The Oxford classification (OC) an internationally adopted standard renal biopsy reporting IgAN, which measures degree histological abnormalities predicts prognosis. Kidney Failure...
The 2,2',4,4',6,6'hexanitrostilbene, HNS, nucleant, used in the crystallisation of 2,4,6,trinitrotoluene, TNT, was precipitated from molten TNT and examined by differential scanning calorimetry, DSC, at several stages during purification vacuum sublimation. During a broad endotherm, associated with nucleant decomposition, which could be resolved into two endotherms, depending on sublimation temperature, observed. Pure prepared 70‡C showed similar behaviour thermal annealing for extended...