- RNA and protein synthesis mechanisms
- Fungal Biology and Applications
- Polyamine Metabolism and Applications
- Bacteriophages and microbial interactions
- Fungal and yeast genetics research
- Fungal Plant Pathogen Control
- PI3K/AKT/mTOR signaling in cancer
- Plant nutrient uptake and metabolism
- Bacterial Genetics and Biotechnology
Université Libre de Bruxelles
2019-2021
Délégation Paris 7
2017
Sorbonne Paris Cité
2017
Institut Pasteur
2017
Université Paris Cité
2017
Centre National de la Recherche Scientifique
2017
To adjust cell growth and metabolism according to environmental conditions, the conserved TORC1 signaling network controls autophagy, protein synthesis, turnover. Here, we dissected signals controlling phosphorylation activity of TORC1-effector kinase Npr1, involved in tuning plasma membrane permeability nitrogen sources. By evaluating a role pH as signal, show that, although transient cytosolic acidification accompanies source entry is correlated rapid TORC1-dependent drop not prerequisite...
Trichoderma atroviride (Ascomycota, Sordariomycetes) is a well-known mycoparasite applied for protecting plants against fungal pathogens. Its mycoparasitic activity involves processes shared with plant and human pathogenic fungi such as the production of cell wall degrading enzymes secondary metabolites tightly regulated by environmental cues. In eukaryotes, conserved Target Rapamycin (TOR) kinase serves central regulator cellular growth in response to nutrient availability. Here we describe...