A5018828083- Lipid Membrane Structure and Behavior
- Acoustic Wave Resonator Technologies
- Polymer Surface Interaction Studies
- Supramolecular Self-Assembly in Materials
- Mechanical and Optical Resonators
- Thin-Film Transistor Technologies
- Colorectal Cancer Surgical Treatments
- Bacterial Identification and Susceptibility Testing
- Nanofabrication and Lithography Techniques
- ZnO doping and properties
- Dysphagia Assessment and Management
- Molecular Biology Techniques and Applications
- Elasticity and Material Modeling
- Voice and Speech Disorders
- Advanced Biosensing Techniques and Applications
- Force Microscopy Techniques and Applications
- Neurological Disease Mechanisms and Treatments
- Virology and Viral Diseases
- Flavonoids in Medical Research
- Nuclear Receptors and Signaling
- Graphene research and applications
- Gastric Cancer Management and Outcomes
- Nanopore and Nanochannel Transport Studies
- Lysosomal Storage Disorders Research
- Silicon Nanostructures and Photoluminescence
Soonchunhyang University Hospital
2024
Soonchunhyang University
2024
Yonsei University
2024
Nanyang Technological University
2013-2016
Hanyang University Seoul Hospital
2016
Institute for Soldier Nanotechnologies
2014
Massachusetts Institute of Technology
2010-2014
Dongguk University
2013
Whitehead Institute for Biomedical Research
2010
Sogang University
2001-2005
Active targeting of nanoscale drug carriers can improve tumor-specific delivery; however, cellular heterogeneity both within and among tumor sites is a fundamental barrier to their success. Here, we describe microenvironment-responsive layer-by-layer (LbL) polymer carrier that actively targets tumors based on two independent mechanisms: pH-dependent uptake at hypoxic pH hyaluronan-directed cell-surface CD44 receptor, well-characterized biomarker for breast ovarian cancer stem cells. Hypoxic...
Planar lipid bilayers on solid supports mimic the fundamental structure of biological membranes and can be investigated using a wide range surface-sensitive techniques. Despite these advantages, planar bilayer fabrication is challenging, there are no simple universal methods to form such diverse material substrates. One novel recently proposed proven silicon dioxide involves deposition in organic solvent exchange influence phase adsorbed lipids. To scrutinize specifics this solvent-assisted...
The adhesion of lipid vesicles to solid supports represents an important step in the molecular self-assembly model membrane platforms. A wide range experimental parameters are involved controlling this process, including substrate material and topology, composition, vesicle size, solution pH, ionic strength, osmotic pressure. At present, it is not well understood how magnitude direction pressure exerted on a influence corresponding adsorption kinetics. In work, using quartz crystal...
Abstract Microfabricated devices are useful tools for manipulating and interrogating large numbers of single cells in a rapid cost‐effective manner, but connecting these systems to the existing platforms used routine high‐throughput screening libraries remains challenging. Methods sort individual interest from custom microscale standardized culture dishes an efficient automated manner without affecting viability critical. Combining commercially available instrument colony picking...
Poly(l-lysine) (PLL) adsorption onto various materials has been widely applied as a surface modification strategy and layer-by-layer fabrication method. Considering the role of electrostatic charges, detailed understanding influence solution pH on PLL process is important for optimization coating protocols. Herein, different polar hydrophilic substrates—silica, an amine-terminated self-assembled monolayer (SAM) gold, carboxyl-terminated SAM gold—across range conditions was investigated using...
// Su Min Lim 1,2,* , Byung-Ok Choi 3,* Seong-il Oh 4,* Won Jun 5 Ki-Wook 2,6 Minyeop Nahm 2 Yuanchao Xue 7 Jae Hyeok Ji Young Young-Eun Kim 8 Ki Wha Chung 9 Xiang-Dong Fu 10 Chang-Seok 11 and Seung Hyun 1 Biomedical Research Institute, Hanyang University, Seoul, Republic of Korea Cell Therapy Center, University Hospital, 3 Department Neurology Neuroscience Samsung Medical Sungkyunkwan School Medicine, 4 Neurology, Busan Paik Inje College Busan, Sheikh Khalifa Specialty Ras Al Khaimah,...
Mesa-structure SL-APDs were fabricated using three different passivation materials, benzocyclobutene (BCB), polyimide and SiNx. The best dark current was from BCB passivated devices with a mesa-diameter of 30 µm 38 nA when operated, approximately factor 10 improvement compared other reports.
An accurate microscopical analysis of blood smears requires a reproducible and convenient method staining. Solution-based staining procedures can be cumbersome. Especially in low- middle-income countries, the lack skilled technicians adequate laboratory facilities, as well insufficient water reagent quality, often become confounding factors. To overcome these obstacles, we developed new cell based on sequential stamping agarose gel patches that contain eosin, methylene blue/oxidized blue,...
In the era of precision oncology, multicolor fluorescence imaging has become a core technology for multiplexed molecular analysis cellular and tissue specimens. However, conventional solution-based staining is labor-intensive time-consuming requires considerable expertise to yield optimal results, which creates difficulties employing this in resource-limited settings. Here, we report new immunostaining method based on hydrogel stamping, simple, fast, easy use, reproducible. We showed that...
Bamboo salt (BS) and soy sauce (SS) are traditional foods in Asia, which contain antioxidants that have cytoprotective effects on the body. The majority of SS products high levels common salt, consumption has been associated with numerous detrimental However, BS may be considered a healthier substitute to salt. present study hypothesized made from BS, known as bamboo (BSSS), possess enhanced properties; this was evaluated using hydrogen peroxide (H2O2)‑induced neuronal cell death rat model....
The quartz crystal microbalance (QCM) is increasingly used for monitoring the interfacial interaction between surfaces and macromolecules such as biomaterials, polymers, metals. Recent QCM applications deal with several types of liquids various viscous macromolecule compounds, which behave differently from Newtonian liquids. To properly monitor interactions, it crucial to understand influence non-Newtonian fluid on measurement response. As a quantitative indicator behavior, we resonator...
Background: Aseptic meningitis comprises meningeal inflammation and cerebrospinal fluid (CSF) pleocytosis without positive Gram stain culture. Regional differences exist in the prevalence of viral etiologies aseptic meningitis. We aimed to assess immunocompetent adults, focusing on herpes simplex virus type 2 (HSV-2). Methods: This study retrospectively analyzed adults diagnosed with at a Korean tertiary care hospital from 2016 2018. was defined through clinical CSF analysis. compared...
A simple aerodynamic calculation program for high Mach number flow is developed by combining the modified Newtonian method with Tannehill's curve fits thermodynamic properties of air in equilibrium state. Aerodynamic characteristics a parabolic nose are predicted and compared CFD(Computational Fluid Dynamics) analysis results. Comparison shows good agreements, expected to be practical tool slender body flow.
의 대장직장폴립을 절제할 수 있었고 이로 인해서 수술을 통한 폴립 제거는 내시경을 통해서 완전 절제가 어렵거나 절제 후 잔존암이 있 거나 국소전이의 가능성이 높을 경우에 한해서 시행되고 있다.대장내시경 폴립절제술은 내시경의 구조상 생검겸자공 위치가 5-
Paralysis of the left recurrent laryngeal nerve as a complication various types heart disease is well known clinical entity. It recognized number conditions including arterial septal defect, patent ductus arteriosus, primary pulmonary hypertension, Eisenmenger’s syndrome and aortic aneurysm. We report case palsy associated with huge thoracic aneurysm in an old man history hypertension. (J Clinical Otolaryngol 2008;19:235-238)