Xu Chen

ORCID: 0000-0002-2008-9191
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About
Contact & Profiles
Research Areas
  • Vibrio bacteria research studies
  • Immune Response and Inflammation
  • Aquaculture disease management and microbiota
  • Probiotics and Fermented Foods
  • Dermatology and Skin Diseases
  • Fish Biology and Ecology Studies
  • Autoimmune Bullous Skin Diseases
  • Renal function and acid-base balance
  • Cytomegalovirus and herpesvirus research
  • Liver Disease Diagnosis and Treatment
  • Fermentation and Sensory Analysis
  • Meat and Animal Product Quality
  • Cancer Research and Treatments
  • Ichthyology and Marine Biology
  • Animal Diversity and Health Studies
  • Antimicrobial Peptides and Activities
  • Liver Disease and Transplantation
  • Plant Pathogens and Fungal Diseases
  • Marine and fisheries research
  • Hematological disorders and diagnostics
  • Food Quality and Safety Studies
  • Asthma and respiratory diseases
  • Gut microbiota and health
  • Dermatological and Skeletal Disorders
  • Fungal Biology and Applications

Chinese Academy of Medical Sciences Dermatology Hospital
2018-2023

Chinese Academy of Medical Sciences & Peking Union Medical College
2023

Nanjing Medical University
2023

Fujian Academy of Agricultural Sciences
2019-2021

Fujian Normal University
2019

Children's Hospital of Zhejiang University
2009-2018

Chinese Academy of Fishery Sciences
2016

Shaanxi Normal University
2013

Hong Kong Food Council
2012

Zhejiang University
2011

This study reports length-weight relationships of yellowfin tuna Thunnus albacares, skipjack Katsuwonus pelamis, yaito Euthynnus yaito, and blue round scad Decapterus maruadsi from Mischief Reef, South China Sea caught by light falling-net fishing method.A total 311 individuals were sampled in this study.The tuna, can be expressed as W = 0.0096×L 2.548 (R 2 0.9243), 2.7593×L 1.4437 0.8468), 0.0079×L 3.1983 0.9087), 0.0049×L 3.3415 0.8924), respectively.To the authors' best knowledge,...

10.20431/2454-7670.0204005 article EN International Journal of Innovative Studies in Aquatic Biology and Fisheries 2016-01-01

Tumor necrosis factor (TNF) plays an important role in inflammatory cytokine storm. Over-secretion of TNF by the host response to infection aggravates disease. expression level is positively correlated with mortality caused some bacterial infections. Therefore, using antibody may alleviate inflammation resist The function fish TNF-b still unclear. In this study, models Vibrio vulnificus FJ03-X2 strain high pathogenicity and strong virulence were established zebrafish ( Danio rerio )...

10.3389/fvets.2021.741242 article EN cc-by Frontiers in Veterinary Science 2021-11-18

Vibrio vulnificus is an aquatic pathogen that can cause primary sepsis and soft tissue infection. CpG oligodeoxynucleotides (CpG-ODN) are a type of essential immunomodulators, which trigger or enhance immune responses in mammals, fish humans. In this study, we evaluated the effect CpG-ODN 2007 as potential immunostimulant for zebrafish (Danio rerio) infected with V. strain FJ03-X2. Fish injected showed lower mortality rate compared did not receive treatment; survival rates 2007-treated group...

10.1111/are.14944 article EN Aquaculture Research 2020-10-19

Dermal fibroblasts (dFBs) defend against deep bacterial skin infections by differentiating into preadipocytes (pAds) that produce the antimicrobial peptide cathelicidin; this differentiation is known as dermal reactive adipogenesis response. However, role of dFBs in fungal infection remains unknown. Here, we found cathelicidin-producing pAds were present high numbers lesions from patients with cutaneous Candida granulomas. Second, showed albicans (C. albicans) mice robustly triggered...

10.1371/journal.ppat.1011754 article EN cc-by PLoS Pathogens 2023-11-30

Abstract Vibrio vulnificus (V. vulnificus) is an aquatic pathogen that can cause primary sepsis and soft tissue infection. CpG oligodeoxynucleotides (CpG-ODN) are a type of essential immunomodulators, which trigger or enhance immune responses in mammals, fish, humans. In this study, we evaluated the effect CpG-ODN 2007 as potential immunostimulant for zebrafish infected with V. (FJ03-X2). Fish injected showed lower mortality rate compared fish did not receive treatment. The survival rates...

10.1101/780742 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2019-09-24

Aims & Objectives: The epidemiology of hypoxic hepatitis(HH) in children after cardiac surgery are not well documented the literature. objective this study is to describe incidence rate HH surgery, duration and clinical outcomes, as risk factors associated with in-hospital mortality. Methods Data were collected prospectively from all consecutive pediatric patients who underwent open-heart 2007 2015 a regional children's hospital. screened for daily throughout their ICU stay receiving...

10.1097/01.pcc.0000537757.20824.de article EN Pediatric Critical Care Medicine 2018-05-31
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