A5080204409- Protease and Inhibitor Mechanisms
- Peptidase Inhibition and Analysis
- Plant tissue culture and regeneration
- Cell Adhesion Molecules Research
- Bacteriophages and microbial interactions
- Probiotics and Fermented Foods
- Nematode management and characterization studies
- Gut microbiota and health
- Bacterial Genetics and Biotechnology
- Bone and Dental Protein Studies
- Antibiotic Resistance in Bacteria
- Blood Coagulation and Thrombosis Mechanisms
- Bacterial biofilms and quorum sensing
- Oral microbiology and periodontitis research
- Polyamine Metabolism and Applications
- Polysaccharides and Plant Cell Walls
- Composting and Vermicomposting Techniques
- Biofuel production and bioconversion
- Microbial Metabolites in Food Biotechnology
- Protein Hydrolysis and Bioactive Peptides
- Plant Pathogens and Fungal Diseases
- Studies on Chitinases and Chitosanases
- Entomopathogenic Microorganisms in Pest Control
- Biochemical and Structural Characterization
- Genomics and Phylogenetic Studies
Amrita Vishwa Vidyapeetham
2017-2025
Nilamber Pitamber University
2024
West Bengal University of Animal and Fishery Sciences
2020
Central Institute of Fisheries Education
2020
The University of Texas Health Science Center at San Antonio
2008-2014
University of Allahabad
2014
Indian Institute of Technology Kharagpur
2003
Kurukshetra University
1993
Major autolysin (Atl) of Staphylococcus aureusis a cell surface associated peptidoglycan hydrolase with amidase and glucosaminidase domains. Atl enzymes (amidase glucosaminidase) are known to participate in biofilm formation also can bind host matrices. Earlier studies demonstrated the binding Atlwithfibronectin, thrombospondin 1, vitronectin heat shock cognate protein Hsc70. Here, we have shown, mediates attachment S.aureus heparin gelatine as well. The atl mutant strain around 2.5 fold...
Background: Advanced glycation end products (AGEs) have been linked to pathogenic mechanisms of diabetes mellitus. However, little is known about the contribution protein periodontal disease in patients with diabetes. Therefore, this study investigated whether type I collagen (COLI) and fibronectin (FN) modified behavior human gingival fibroblasts (hGFs) ligament (hPDLs). Methods: Procedures for rapid vitro COLI FN used methylglyoxal (MG). Formation AGEs was analyzed by changes migration...
Background: Fibronectin (FN) undergoes fragmentation in periodontal disease sites and poorly healing diabetic wounds. The biologic effects of FN fragments on wound remain unresolved. This study characterized the pattern its cellular behavior compared to intact FN. Methods: Polyclonal antibodies were raised against three defined recombinant segments used analyze gingival crevicular fluid from systemically healthy subjects with diabetes, as well chronic leg foot exudates diabetes....
Approximately 40-50% of municipal solid waste is organic and causing biogenic malodor infections, due to inefficient treatment methods. Biorefinery-based bioremediation valorization in vogue against these conventional strategies since it combines unit operations for better efficiency productivity. Deriving inspiration, the proposed strategy puts together a unique compatible combination processes. This novel two-step workflow involves extraction small molecules using solvents, fermentation...
Recent literature has suggested a novel symbiotic relationship between bacteriophage and metazoan host that provides antimicrobial defense protecting mucosal surface by binding to matrix mucin glycoproteins. Here, we isolated studied different bacteriophages specifically interact with human extracellular molecules such as fibronectin, gelatin, heparin demonstrated their potency for protection against microbial infections. We showed subpopulations of work clinical isolates Escherichia coli...
Platelet-derived growth factor BB and its receptor (PDGFRβ) play a pivotal role in the development of renal glomerular mesangial cells. Their roles increased cell proliferation during mesangioproliferative glomerulonephritis have long been noted, but operating logic signaling mechanisms regulating these changes remains poorly understood. We examined recently identified MAPK, Erk5, this process. PDGF activating phosphorylation Erk5 tyrosine proteins time-dependent manner. A pharmacologic...
Environmental enteropathy (EE), a chronic small intestine disease characterized by gut inflammation, is widely prevalent in low-income countries and hypothesized to be caused continuous exposure fecal contamination. Targeted nutritional interventions using potential probiotic strains from fermented foods can an effective strategy inhibit enteric pathogens prevent inflammation.We isolated rice water lemon pickle investigated their cell surface properties, antagonistic adhesion HT-29 cells,...
Interactions of matrix metalloproteinase-2 (MMP-2) with native and denatured forms several types collagen are mediated by the binding domain (CBD). CBD positions substrates relative to catalytic site is essential for their cleavage. Our previous studies identified a on alpha1(I) chain. The corresponding synthetic peptide P713 bound high affinity was used in this study identify specific residues NMR analysis (15)N-labeled complexed P713. Results obtained showed that caused chemical shift...
The current COVID-19 pandemic situation has posed a significant threat to human health. This calls for versatile facemask filters with high filtration efficiency and biocidal activity. Herein, we have rationally designed three-layered nanofilter mask consisting of electrospun polycaprolactone (PCL) curcumin as nanocoating on polypropylene spunbond membrane. nanomask thus developed had particulate 96.8 ± 0.1%, good breathability (64 2 Pa) quality factor (0.052 0.0005 Pa–1) coating thickness...
Abstract Bacterial pathogens are fostered in and transmitted through wastewater. Hence, monitoring their impact on sanitation hygiene is imperative. As part of the process, culture-based methodologies primarily used, which centre use selective differential media. Media available today are, at best, difficult to formulate and, worst, prohibitively expensive. To address this lacuna, study proposes a medium for Klebsiella spp. blue agar (KBA) completely against selected gram-positive bacteria (...
We report the draft genome sequence of Escherichia coli ASBT-1, a representative E. type 155 (ST155), obtained from India. Considering known wide variety pathogenic and antibiotic resistance potentials, this strain should be great interest for detailed comparative genomic analysis.
The study was aimed to assess, in monetary units the services gained from mangrove ecosystem of Uttara Kannada district Karnataka, India and analyse people's perception about importance mangroves besides their willingness pay (WTP) for its conservation.Study conducted with double-bounded dichotomous approach poll questions were asked respondents.A binary logistic regression model applied Willingness Pay respondents develop maintain mangroves.Respondents areas less aware such as carbon...
Robust control of pathogens in sewage facilitates safe reuse wastewater rich valuable nutrients for potential valorization through biological means. Aspergillus niger is widely reported bioremediation but studies on enteric are very sparse. So, this study aimed at exploring the antibacterial and nematicidal activity A. culture filtrate (ACF). Antibacterial ACF (Klebsiella pneumoniae, Pseudomonas aeruginosa, Vibrio cholerae, Salmonella enterica, Shigella dysenteriae, Escherichia coli,...
Abstract Wastewater malodour is the proverbial ‘elephant in room’ notwithstanding its severe implications on sanitation, health, and hygiene. The predominant malodorous compounds associated with wastewater treatment plants toilets are volatile organic compounds, such as hydrogen sulphide, ammonia, methanethiol, acids. Among them, methanethiol warrants more attention owing to relatively low olfactory threshold cytotoxicity. This requires an efficient odour-abatement method since conventional...
Fibronectin (FN) is an important cell adhesion molecule that used widely to characterize behavior. Preparations of FN purified from human plasma by gelatin-Sepharose affinity chromatography typically also contain gelatin-binding gelatinases may cleave FN, reduce its stability and alter biological activities. Available methods for separating are resource demanding. Therefore, our objective was devise a time- cost-efficient protocol purification gelatinase-free FN.Experiments tested the...