A5060011150- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Fungal Infections and Studies
- HIV, Drug Use, Sexual Risk
- Pneumocystis jirovecii pneumonia detection and treatment
- Homelessness and Social Issues
- Adolescent Sexual and Reproductive Health
- Antifungal resistance and susceptibility
- Food Security and Health in Diverse Populations
- Tuberculosis Research and Epidemiology
- HIV/AIDS drug development and treatment
- Parasitic Diseases Research and Treatment
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- HIV-related health complications and treatments
- SARS-CoV-2 detection and testing
- Insects and Parasite Interactions
- Nail Diseases and Treatments
- HIV/AIDS oral health manifestations
- Geriatric Care and Nursing Homes
- Insect symbiosis and bacterial influences
- Housing, Finance, and Neoliberalism
- Poverty, Education, and Child Welfare
- Immunodeficiency and Autoimmune Disorders
- Parasites and Host Interactions
Centers for Disease Control and Prevention
2017-2024
Fundación Juan March
2021
Cotton (United States)
2021
Center for Global Health
2018-2020
CDC Foundation
2020
Division of Parasitic Diseases and Malaria
2018
Vanderbilt University Medical Center
2015
Vanderbilt University
2012-2013
In response to reported coronavirus disease 2019 (COVID-19) outbreaks among people experiencing homelessness (PEH) in other US cities, we conducted multiple, proactive, facility-wide testing events for PEH living sheltered and unsheltered service staff Atlanta, Georgia. We describe the severe acute respiratory syndrome 2 (SARS-CoV-2) prevalence associated symptoms, review shelter infection prevention control (IPC) policies.PEH were tested SARS-CoV-2 by reverse transcription polymerase chain...
Background: Earlier antiretroviral therapy (ART) may decrease progression to advanced HIV disease (AHD) with CD4 count of <200 cells per cubic millimeter or clinical sequelae. We assessed factors associated AHD among people living before and during the “test treat” era. Setting: The African Cohort Study prospectively enrolls adults without from 12 clinics in Uganda, Kenya, Tanzania, Nigeria. Methods: Enrollment evaluations included history, physical examination, laboratory testing....
HIV voluntary counseling and testing (VCT) utilization remains low in many sub-Saharan African countries, particularly remote rural settings. We sought to identify factors associated with service awareness uptake of VCT among female heads household Zambézia Province north-central Mozambique which is characterized by high prevalence (12.6%), poverty, suboptimal health access utilization.Our population-based survey was administered a representative two-stage cluster sample using sampling frame...
Background As Zimbabwe approaches epidemic control of HIV, programs now prioritize viral load over CD4 monitoring, making it difficult to identify persons living with HIV (PLHIV) suffering from advanced disease (AD). We present an analysis cross-sectional ZIMPHIA data, highlighting PLHIV AD and concurrent suppression (VLS). Methods collected blood specimens for testing 22,501 consenting adults (ages 15 years older); 3,466 had VL results. Household used the national serial algorithm, those...
We investigated patients with potential severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection in the United States during May-July 2020.We conducted case finding for SARS-CoV-2 through Emerging Infections Network. Cases reported were screened laboratory and clinical findings of followed by requests medical records specimens. Available abstracted to characterize patient demographics, comorbidities, course, test results. Submitted specimens underwent further testing,...
Local agencies across the United States have identified public health isolation sites for individuals with coronavirus disease 2019 (COVID-19) who are not able to isolate in residence.
Background Careful monitoring for recrudescence of Wuchereria bancrofti infection is necessary in communities where mass drug administration (MDA) the elimination lymphatic filariasis (LF) as a public health problem has been stopped. During post-MDA period, transmission assessment surveys (TAS) are recommended by World Health Organization to monitor presence parasite humans. Molecular xenomonitoring (MX), method which mosquito population monitored, also proposed sensitive determine whether...
Some aspects of HIV-related stigma have been shown to be a barrier HIV services uptake and adherence antiretroviral treatment (ART). Distinguishing which domains impact can enhance the efficacy efficiency stigma-reduction interventions. The relationships between use voluntary counseling testing (VCT) two community identified through factor analysis, negative labeling/devaluation social exclusion, were investigated among 3749 female heads household. Data from general household survey...
Gastrointestinal histoplasmosis (GIH) is common in patients with disseminated disease but only rarely comes to clinical attention due the lack of specific signs and symptoms. We report unusual case a 33-year-old Caucasian male advanced AIDS who presented upper GI bleeding from diffuse erosions throughout duodenum. Biopsy lesions revealed small bowel mucosa granulomatous inflammation macrophages intracellular yeasts consistent histoplasmosis. The patient demonstrated significant improvement...
To compare diagnostic tests for onchocerciasis in a setting that has suppressed transmission, randomized, age-stratified study was implemented an area Tanzania had received 15 rounds of annual mass drug administration (MDA) with ivermectin. Study participants (N = 948) from 11 villages underwent questionnaire, skin examination, snips, and blood draw. The burden symptomatic disease low. Ov-16 antibody rapid test (RDT) results were positive 38 (5.5%) participants, 1 (0.5%), (0.4%), 2 (0.8%)...
Despite antiretroviral therapy (ART) scale-up among people living with HIV (PLHIV), those advanced disease (AHD) (defined in adults as CD4 count <200 cells/mm3 or clinical stage 3 4), remain at high risk of death from opportunistic infections. The shift routine baseline testing towards viral load conjunction "Test and Treat" has limited AHD identification.We used official estimates existing epidemiological data to project deaths tuberculosis (TB) cryptococcal meningitis (CM) PLHIV-initiating...
For adults and adolescents, the World Health Organization defines advanced HIV disease (AHD) as a CD4 (cluster of differentiation 4) count <200 cells/mm3 or clinical stage 3 4 event. We describe outcomes in cohort AHD patients at two regional hospitals Lesotho. From November 2018-June 2019, we prospectively enrolled eligible (≥15 years) not on antiretroviral therapy (ART) presenting with WHO-defined into differentiated model care for (including rapid ART initiation) followed them six months....
Abstract Background Determining the prevalence of pre-treatment HIV drug resistance (PDR) is important to assess effectiveness first-line therapies. To determine PDR in Papua New Guinea (PNG), we conducted a nationally representative survey. Methods We used two-stage cluster sampling method recruit treatment initiators with and without prior exposure antiretroviral therapies (ART) selected clinics. Dried blood spots were collected tested for PDR. Results A total 315 sequences available...
Abstract Background Persons experiencing homelessness (PEH) often do not have sufficient resources to practice public health interventions. PEH may reside at overcrowded shelters, poor access care, and suffer from significant co-morbid conditions. In this study, we describe prevalence of COVID-19 amongst homeless service staff in Atlanta, Georgia, as well demographic data, underlying conditions, symptoms. Methods response the pandemic providers were offered PCR testing for SARS-CoV-2 via...
Abstract Background In the “test and treat” era, early ART may decrease prevalence of advanced HIV disease (AHD), defined as having a CD4 cell count &lt; 200 cells/µL or World Health Organization (WHO) clinical stage III IV disease. We assessed trends in AHD coverage describe factors associated with among adults living (LWH) across four countries before during era. Methods The African Cohort Study (AFRICOS) is prospective cohort enrolling at risk for LWH from 12 facilities Uganda, Kenya,...
Abstract Background : Determining the prevalence of pre-treatment HIV drug resistance (PDR) is important to assess effectiveness first-line therapies. To determine PDR in Papua New Guinea (PNG), we conducted a nationally representative survey. Methods We used two-stage cluster sampling method recruit treatment initiators with and without prior exposure antiretroviral therapies (ART) selected clinics. Dried blood spots were collected tested for PDR. Results A total 315 sequences available...