Tom Chiller

ORCID: 0000-0002-2251-8033
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About
Contact & Profiles
Research Areas
  • Antifungal resistance and susceptibility
  • Fungal Infections and Studies
  • Nail Diseases and Treatments
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Plant Pathogens and Fungal Diseases
  • Infectious Diseases and Mycology
  • Neutropenia and Cancer Infections
  • Salmonella and Campylobacter epidemiology
  • HIV/AIDS oral health manifestations
  • Cytomegalovirus and herpesvirus research
  • Actinomycetales infections and treatment
  • Antibiotic Use and Resistance
  • Antimicrobial Resistance in Staphylococcus
  • Viral gastroenteritis research and epidemiology
  • HIV/AIDS Research and Interventions
  • Tuberculosis Research and Epidemiology
  • Bacterial Identification and Susceptibility Testing
  • Listeria monocytogenes in Food Safety
  • Parasitic Diseases Research and Treatment
  • Respiratory and Cough-Related Research
  • Phytoplasmas and Hemiptera pathogens
  • Yeasts and Rust Fungi Studies
  • Studies on Chitinases and Chitosanases
  • Food Safety and Hygiene
  • Plant Pathogens and Resistance

Centers for Disease Control and Prevention
2016-2025

National Center for Emerging and Zoonotic Infectious Diseases
2015-2024

AID Atlanta
2019-2024

Mucolipidosis IV Foundation
2024

Waterborne Environmental (United States)
2011-2023

Philadelphia Department of Public Health
2022

Hospital of the University of Pennsylvania
2022

World Health Organization Regional Office for the Americas
2022

Translational Genomics Research Institute
2011-2020

Administración Nacional de Laboratorios e Institutos de Salud
2020

Tabled 1Table of ContentsAuthor List1143Preface1145Executive Summary1146Background to HCT1147Hematopoietic Cell Graft Safety1153Bacterial Infections1156Viral Infections1159Fungal Infections1170Regionally Limited or Rare Infections1176Infection Control and Prevention in Health care Facilities1182Safe Living after Transplantation1195Vaccinations1203References1207Appendices1229 Open table a new tab Marcie Tomblyn, University Minnesota, Minneapolis, MN Tom Chiller, Centers for Disease...

10.1016/j.bbmt.2009.06.019 article EN cc-by-nc-nd Biology of Blood and Marrow Transplantation 2009-09-10

Invasive fungal infections (IFIs) are a major cause of morbidity and mortality among organ transplant recipients. Multicenter prospective surveillance data to determine disease burden secular trends lacking.The Transplant-Associated Infection Surveillance Network (TRANSNET) is consortium 23 US centers, including 15 that contributed the recipient dataset. We prospectively identified IFIs recipients from March, 2001 through 2006 at these sites. To explore trends, we calculated 12-month...

10.1086/651262 article EN Clinical Infectious Diseases 2010-03-10

The incidence and epidemiology of invasive fungal infections (IFIs), a leading cause death among hematopoeitic stem cell transplant (HSCT) recipients, are derived mainly from single-institution retrospective studies.The Transplant Associated Infections Surveillance Network, network 23 US centers, prospectively enrolled HSCT recipients with proven probable IFIs occurring between March 2001 2006. We collected denominator data on all HSCTs preformed at each site clinical, diagnostic, outcome...

10.1086/651263 article EN Clinical Infectious Diseases 2010-03-10

Candida auris, a multidrug-resistant yeast that causes invasive infections, was first described in 2009 Japan and has since been reported from several countries. To understand the global emergence epidemiology of C. we obtained isolates 54 patients with auris infection Pakistan, India, South Africa, Venezuela during 2012–2015 type specimen Japan. Patient information available for 41 isolates. We conducted antifungal susceptibility testing whole-genome sequencing (WGS). Available clinical...

10.1093/cid/ciw691 article EN public-domain Clinical Infectious Diseases 2016-10-15

Fungal diseases range from relatively-minor superficial and mucosal infections to severe, life-threatening systemic infections. Delayed diagnosis treatment can lead poor patient outcomes high medical costs. The overall burden of fungal in the United States is challenging quantify, because they are likely substantially underdiagnosed. To estimate total, national, direct costs associated with a healthcare payer perspective, we used insurance claims data Truven Health MarketScan 2014 Research...

10.1093/cid/ciy776 article EN public-domain Clinical Infectious Diseases 2018-09-06

Candidemia is common and associated with high morbidity mortality; changes in population-based incidence rates have not been reported.We conducted active, surveillance metropolitan Atlanta, Georgia, Baltimore City/County, Maryland (combined population 5.2 million), during 2008-2011. We calculated candidemia antifungal drug resistance compared prior (Atlanta, 1992-1993; Baltimore, 1998-2000).We identified 2675 cases of 2329 isolates 3 years surveillance. Mean annual crude per 100 000...

10.1093/cid/cis697 article EN Clinical Infectious Diseases 2012-08-14

Invasive pulmonary aspergillosis is increasingly reported in patients with influenza admitted to the intensive care unit (ICU). Classification of influenza-associated (IAPA) using current definitions for invasive fungal diseases has proven difficult, and our aim was develop case IAPA that can facilitate clinical studies. A group 29 international experts reviewed insights into epidemiology, diagnosis management proposed a definition through process informal consensus. Since may wide range...

10.1007/s00134-020-06091-6 article EN cc-by-nc Intensive Care Medicine 2020-06-22

Background. Invasive aspergillosis (IA) is an important cause of morbidity and mortality in hematopoietic stem cell transplant (HSCT) solid organ (SOT) recipients. The purpose this study was to evaluate factors associated with patients IA.

10.1086/652768 article EN Clinical Infectious Diseases 2010-05-07

Recent reports have demonstrated a decline in bacterial bloodstream infections (BSIs) following adherence to central line insertion practices; however, declines been less evident for BSIs due Candida species.We conducted active, population-based laboratory surveillance candidemia metropolitan Atlanta, GA and Baltimore, MD over 5-year period. We calculated annual incidence antifungal drug resistance rates.We identified 3,848 cases from 2008-2013. Compared with 2008, per 100,000 person-years...

10.1371/journal.pone.0120452 article EN public-domain PLoS ONE 2015-03-30

A large aggregate collection of clinical isolates aspergilli (n = 218) from transplant patients with proven or probable invasive aspergillosis was available the Transplant-Associated Infection Surveillance Network, a 6-year prospective surveillance study. To determine Aspergillus species distribution in this collection, were subjected to comparative sequence analyses by use internal transcribed spacer and beta-tubulin regions. fumigatus predominant recovered, followed A. flavus niger....

10.1128/jcm.01070-09 article EN Journal of Clinical Microbiology 2009-08-13

Between 2008 and 2011, population-based candidemia surveillance was conducted in Atlanta, GA, Baltimore, MD. Surveillance had been previously performed Atlanta 1992 to 1993 Baltimore 1998 2000, making this the first over multiple time points United States. From 2,675 identified cases of current surveillance, 2,329 Candida isolates were collected. albicans no longer comprised majority but remained most frequently isolated species (38%), followed by glabrata (29%), parapsilosis (17%),...

10.1128/jcm.01283-12 article EN Journal of Clinical Microbiology 2012-08-09

In the 10 months since first confirmed case of coronavirus disease 2019 (COVID-19) was reported in United States on January 20, 2020 (1), approximately 13.8 million cases and 272,525 deaths have been States. On October 30, number new a single day exceeded 100,000 for time, by December 2 had reached daily high 196,227.* With colder weather, more time spent indoors, ongoing U.S. holiday season, silent spread disease, with 50% transmission from asymptomatic persons (2), has entered phase...

10.15585/mmwr.mm6949e2 article EN MMWR Morbidity and Mortality Weekly Report 2020-12-04

ABSTRACT Candida glabrata is the second leading cause of candidemia in U.S. hospitals. Current guidelines suggest that an echinocandin be used as primary therapy for treatment C. disease due to high rate resistance fluconazole. Recent case reports indicate echinocandins may increasing. We performed susceptibility testing on 1,380 isolates collected between 2008 and 2013 from four cities, Atlanta, Baltimore, Knoxville, Portland. Our analysis showed 3.1%, 3.3%, 3.6% were resistant...

10.1128/aac.03255-14 article EN Antimicrobial Agents and Chemotherapy 2014-06-03

Abstract Background Candida auris is a multidrug-resistant yeast associated with hospital outbreaks worldwide. During 2015–2016, multiple were reported in Colombia. We aimed to understand the extent of contamination healthcare settings and characterize molecular epidemiology C. Methods sampled patients, patient contacts, workers, environment 4 hospitals recent outbreaks. Using standardized protocols, people swabbed at different body sites. Patient procedure rooms sectioned into zones...

10.1093/cid/ciy411 article EN public-domain Clinical Infectious Diseases 2018-05-08

The Summary of Notifiable Infectious Diseases and Conditions-United States, 2014 (hereafter referred to as the summary) contains official statistics, in tabular graphic form, for reported occurrence nationally notifiable infectious diseases conditions United States 2014. Unless otherwise noted, data are final totals June 30, 2015. These statistics collected compiled from reports sent by U.S. state territory, New York City, District Columbia health departments National Surveillance System...

10.15585/mmwr.mm6354a1 article EN MMWR Morbidity and Mortality Weekly Report 2016-10-13
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