- Nail Diseases and Treatments
- Plant Pathogens and Fungal Diseases
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Infectious Diseases and Mycology
- Milk Quality and Mastitis in Dairy Cows
- Probiotics and Fermented Foods
- Fungal Biology and Applications
- Dermatology and Skin Diseases
- Immune Response and Inflammation
- Veterinary Oncology Research
- Virus-based gene therapy research
- Yeasts and Rust Fungi Studies
- Mycotoxins in Agriculture and Food
- Microbial infections and disease research
- Immunotherapy and Immune Responses
- Plant Disease Resistance and Genetics
- Mycobacterium research and diagnosis
- Cell Adhesion Molecules Research
- Bee Products Chemical Analysis
- Platelet Disorders and Treatments
- Antimicrobial Peptides and Activities
- Plant Pathogens and Resistance
- Blood groups and transfusion
- Cutaneous lymphoproliferative disorders research
Nihon University
2015-2025
Teikyo University
1998-2025
Otsuka (Japan)
2004-2025
Jikei University School of Medicine
2022-2024
Juntendo University
2017
Gifu University
2011
National Institute of Animal Health
2011
Tochigi Cancer Center
2010
Centers for Disease Control and Prevention
2008-2009
University of Bern
2008
A large aggregate collection of clinical isolates aspergilli (n = 218) from transplant patients with proven or probable invasive aspergillosis was available the Transplant-Associated Infection Surveillance Network, a 6-year prospective surveillance study. To determine Aspergillus species distribution in this collection, were subjected to comparative sequence analyses by use internal transcribed spacer and beta-tubulin regions. fumigatus predominant recovered, followed A. flavus niger....
Five isolates of a novel species the yeast genus Malassezia were isolated from animals in Japan and Brazil. Phylogenetic trees based on D1/D2 domains large-subunit (26S) rDNA sequences nucleotide internal transcribed spacer 1 region showed that conspecific belonged to . They related closely dermatis sympodialis , but clearly distinct these two other six have been reported, indicating they should be classified as species, nana sp. nov. Morphologically physiologically, M. resembles can...
Sporothrix ( Ophiostomatales ) comprises species that are pathogenic to humans and other mammals as well environmental fungi. Developments in molecular phylogeny have changed our perceptions about the epidemiology, host-association, virulence of . The classical agent sporotrichosis, schenckii , now several nested a clinical clade with S. brasiliensis globosa luriei To gain more precise view outbreaks dynamics, structure, origin genetic variation within among populations we applied three sets...
Abstract Terbinafine (TRF) has been used in the treatment of fungal infections for more than 20 years. Recently, TRF‐resistant Trichophyton interdigitale and T. rubrum strains have isolated from human patients worldwide. However, an epidemiological study Japanese not investigated. In present study, antifungal susceptibility testing was performed on clinical isolates to assess TRF‐resistance patterns strains. We also sequenced squalene epoxidase ( SQLE ) encoding gene Two hundred ten were...
Sporotrichosis is the main subcutaneous mycosis worldwide transmitted by animal or plant vectors and often escalates to outbreaks epidemics. The current cat-transmitted sporotrichosis driven Sporothrix brasiliensis has become a significant public health issue in South America. Transmission dynamics remain enigmatic due lack of development polymorphic markers for molecular epidemiological analysis. This study used high-throughput mining strategy characterize simple sequence repeat (SSR) from...
Forty-six strains of Malassezia spp. with atypical biochemical features were isolated from 366 fresh clinical isolates human subjects and dogs. Isolates obtained in this study included 2 (4.7%) lipid-dependent M. pachydermatis isolates; 1 (2.4%) precipitate-producing 6 (14.6%) non-polyethoxylated castor oil (Cremophor EL)-assimilating furfur 37 (34.3%) slooffiae that esculin hydrolyzing, 17 (15.7%) non-tolerant growth at 40 degrees C, (1.9%) assimilated polyethoxylated oil. Although their...
Summary Epidemiological data on the aetiologic agents of feline sporotrichosis in Malaysia have not been reported, though human is reported to be transmitted primarily via cat scratch. To best our knowledge, present report first study molecular epidemiology Sporothrix schenckii isolates from cats with Malaysia. In work, we characterised 18 clinical based properties, including sequence analyses calmodulin gene and rDNA ITS region selective PCR mating type ( MAT ) loci. this study, were...
ABSTRACT Sporotrichosis is one of the most frequent subcutaneous fungal infections in humans and animals caused by members plant-associated, dimorphic genus Sporothrix . Three four medically important species found Brazil have been considered asexual as no sexual stage has ever reported schenckii , brasiliensis or globosa We identified mating type ( MAT ) loci S. (strain 1099-18/ATCC MYA-4821) 5110/ATCC MYA-4823) genomes using comparative genomic approaches to determine ratio these pathogen...
A 2-year-old, exotic shorthair cat presented with baldness and mild scaling on trunk that was confirmed as Microsporum canis (M. canis) infection by the following methods. Wood's lamp trichogram were used to demonstrate fungal elements suggestive of dermatophytosis consistent M. canis. Dermatophyte test medium (DTM) polymerase chain reaction (PCR) for identification. E-test broth microdilution then utilized estimate antifungal minimal inhibitory concentrations (MICs) towards ITZ TRF...
Abstract Trichophyton interdigitale is an anthropophilic species that frequently isolated from tinea unguium and pedis throughout the world. In present study, antifungal susceptibility testing was performed on T. isolates Japanese patients (isolated in 2017–2018; 24 strains) to assess itraconazole ( ITZ ) terbinafine TRF of these strains. E‐test determinations revealed mean minimum inhibitory concentration MIC strains 0.023 mg/L (range, 0.064–1). Clinical Laboratory Standards Institute...
The multi-antifungal drug-resistant strain (NUBS21012) of Trichophyton rubrum was isolated from a patient with recurrent tinea corporis. resistant encoded Phe at codon 393 instead Leu (L393F) in the squalene epoxidase (SQLE) gene. expression genes encoding ATP-binding cassette transporter proteins increased compared to that other strains. This result provides evidence are closely associated azole resistance.
Abstract An epidemiological study of antifungal drug‐resistant dermatophytes was conducted as a follow‐up to our 2020 survey. Dermatophytes were isolated in 2022 from the same dermatology clinics previous study. In total, 288 Trichophyton interdigitale and rubrum clinical isolates obtained human cases dermatophytosis Tokyo, Saitama, Shizuoka, Kumamoto, Japan. Four strains found be resistant terbinafine (TRF) susceptible itraconazole (ITZ), luliconazole (LCZ), ravuconazole (RVZ), three other...