Lisa A. Murphy

ORCID: 0000-0002-2053-6676
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About
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Research Areas
  • Animal Ecology and Behavior Studies
  • Poisoning and overdose treatments
  • Pesticide Residue Analysis and Safety
  • Viral Infections and Vectors
  • Pesticide Exposure and Toxicity
  • Heavy Metal Pollution Remediation
  • Marine and coastal ecosystems
  • Zoonotic diseases and public health
  • Yersinia bacterium, plague, ectoparasites research
  • Microbial infections and disease research
  • Mosquito-borne diseases and control
  • Insect and Pesticide Research
  • Fish Ecology and Management Studies
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Wildlife Ecology and Conservation
  • Marine Toxins and Detection Methods
  • Reservoir Engineering and Simulation Methods
  • Alcoholism and Thiamine Deficiency
  • Vitamin K Research Studies
  • Chemical Reactions and Isotopes
  • Alcohol Consumption and Health Effects
  • Veterinary medicine and infectious diseases
  • Animal testing and alternatives
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Turtle Biology and Conservation

University of Pennsylvania
2014-2025

University of California, Davis
2025

Studies in parts of Europe, New Zealand, and North America indicate uptake anticoagulant rodenticides (ARs) by predatory mammals to be widespread common, with proximity urban agricultural areas being an important driver exposure. Yet, little is known regarding the patterns drivers AR exposure within more forest-dominated landscapes. Across northeastern United States (US), a region spanning Pennsylvania Maine, we tested livers from 597 fisher ( Pekania pennanti ) obtained legal harvest for 11...

10.3389/fevo.2024.1304659 article EN cc-by Frontiers in Ecology and Evolution 2024-02-08

The ability to rapidly respond wildlife health events is essential. However, such are often unpredictable, especially with anthropogenic disturbances and climate-related environmental changes driving unforeseen threats. Many also short-lived go undocumented, making it difficult draw on lessons learned from past investigations. We report the response a mortality event observed predominantly in wild passerines eastern United States. began May 2021 when rehabilitators private citizens reported...

10.3390/vetsci12010048 article EN cc-by Veterinary Sciences 2025-01-11

Zoonotic diseases have received significantly more attention over the last few decades, emerging with increasing frequency and causing majority of notable disease outbreaks in this century, including COVID-19 pandemic. As human activities shifting climate patterns induce changes environment that alter habitat range reservoir species, potential for animal interactions will increase enhance opportunity spillover. Thus, any emergency response preparedness planning must take into account...

10.1101/2025.04.01.646690 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2025-04-03

The Bronx River in Bronx, New York, US spans an area of significant human development and has been subject to historic ongoing industrial contamination. We evaluated the health freeranging native common snapping turtles ( Chelydra serpentina) nonnative invasive red-eared sliders Trachemys scripta) a segment between May July 2012. In 18 nine sliders, complete physical examinations were performed, ectoparasites collected, blood was analyzed for contaminants (mercury, thallium, cadmium,...

10.7589/2017-12-304 article EN Journal of Wildlife Diseases 2018-09-18

Human influences on natural environments are now ubiquitous but manifest in multiple and unique ways depending local communities. Attempts to control, or mediate, pests residences agriculture can impart important negative consequences systems. Secondary exposure anticoagulant rodenticides (ARs) cause numerous adverse effects wild carnivores including death. Few studies have quantified AR prevalence, investigated their pathway of exposure, associations with specific location types the...

10.1139/cjz-2023-0131 article EN Canadian Journal of Zoology 2023-11-29

Mass mortality events in wildlife can be indications of an emerging infectious disease. During the spring and summer 2021, hundreds dead passerines were reported across eastern US. Birds exhibited a range clinical signs including swollen conjunctiva, ocular discharge, ataxia, nystagmus. As part diagnostic investigation, high-throughput metagenomic next-generation sequencing was performed three molecular laboratories on samples from affected birds. Many potentially pathogenic microbes...

10.7589/jwd-d-23-00109 article EN other-oa Journal of Wildlife Diseases 2024-04-05

Abstract Objective To evaluate a point‐of‐care anticoagulant rodenticide lateral flow analyzer for the detection of various compounds. Design Prospective, laboratory study. Setting University teaching hospital. Animals The study utilized serum sample from one healthy canine donor. Samples were centrifuged and samples aliquoted either used within 4 hours or frozen at −70 ° C further quantitative analysis. Interventions spiked with clinically relevant concentrations 1 6 compounds (warfarin,...

10.1111/vec.12140 article EN Journal of Veterinary Emergency and Critical Care 2014-01-06

There is a lack of information on mineral requirements free-ranging white-tailed deer (Odocoileus virginianus). In addition, deficiencies or excesses may play role in the development parasitism/malnutrition syndrome. We measured hepatic values apparently healthy from two sites Virginia, USA, as well with presumptive syndrome during 2005-2007. Deer that were displaying signs emaciation and chronic diarrhea had significantly higher mean levels magnesium (Mg) zinc (Zn) compared deer. Healthy...

10.7589/0090-3558-46.2.525 article EN Journal of Wildlife Diseases 2010-04-01

There is growing interest in using hemp materials as animal feed ingredients, which may raise safety concerns because of the potential transfer active cannabinoids to resultant products origin. Hence, detection and identification feeds would be useful. We developed a simple, fast, sensitive method for simultaneous quantification 4 major by liquid chromatography-tandem mass spectrometry (LC-MS/MS). used simple solvent extraction dilution approach extract from matrix. validated 2 types cattle...

10.1177/10406387231169290 article EN cc-by-nc Journal of Veterinary Diagnostic Investigation 2023-04-17

The presence of insecticides like pyrethrins and synthetic pyrethroids, combined with the synergist piperonyl butoxide, in animal feeds can pose a risk to both human health by contaminating food chain. In this study, simple fast method was developed for simultaneous determination these compounds contaminated using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Sample preparation carried out QuEChERS-based approach, validated acceptable accuracy ranging from 84 115% precision...

10.3390/toxins15060401 article EN cc-by Toxins 2023-06-17

10.1007/s00128-011-0327-7 article EN Bulletin of Environmental Contamination and Toxicology 2011-06-06

Analysis of rumen contents is helpful in solving poisoning cases when ingestion a toxic substance by cattle or other ruminant animals suspected. The most common technique employs extraction the sample with organic solvent followed clean-up method(s) before analysis gas chromatography–mass spectrometry equipped library mass spectra to help identify unknowns. A rapid method using magnesium sulfate, primary secondary amine, and C18 sorbents following principles QuEChERS clean up samples...

10.1177/1040638714541836 article EN Journal of Veterinary Diagnostic Investigation 2014-07-01

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of disease 2019 (COVID-19), which an ongoing global health concern. The exact source virus has not been identified, but it believed that this novel originated in animals; bats particular have implicated as primary reservoir virus. SARS-CoV-2 can also be transmitted from humans to other animals, including tigers, cats, and mink. Consequently, infected people who work directly with could transfer a wild North...

10.1177/1040638721990333 article EN other-oa Journal of Veterinary Diagnostic Investigation 2021-02-01

Abstract A simple and highly sensitive LC/MS method was developed for the simultaneous determination of six ionophores—lasalocid, monensin, laidlomycin, maduramycin, salinomycin, narasin—in feed. The procedure involved extraction 1 g feed with 4 mL methanol–water (9 + 1, v/v) by shaking on a platform shaker 45 min. After centrifugation, extracts were diluted (75 25, analyzed without any cleanup. analysis performed Betasil C18 column (150 × 4.6 mm id, 5 μm particle size) connected to an...

10.5740/jaoacint.11-023 article EN Journal of AOAC International 2012-07-01

10.1053/j.jepm.2015.08.003 article EN Journal of Exotic Pet Medicine 2015-08-21

Investigations of wildlife diseases and mortality events can sometimes lead to inconclusive results due limitations in diagnostics combined with an ever-increasing number emerging viruses. The use tools such as unbiased metagenomic next generation sequencing (mNGS) facilitate the identification causative agents where conventional investigation methods fail. We performed a retrospective mNGS analysis on RNA isolated from postmortem samples collected during black vulture ( Coragyps atratus ,...

10.1101/2024.12.21.629921 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-12-22

Abstract Background: Aflatoxins are one of the most heavily regulated mycotoxins in agriculture throughout world. A variety tests used for detection, including rapid methods that preferred when a large number samples need to be quickly screened implement an immediate action. However, method developed screening specific commodity presence requires further validation demonstrate its suitability additional matrices. Objective: In this study, study was undertaken evaluate aflatoxin B1 (AFB1) dry...

10.5740/jaoacint.19-0020 article EN Journal of AOAC International 2019-10-18

ABSTRACT Mass mortality events in wildlife can be indications of an emerging infectious disease. During the spring and summer 2021, hundreds dead passerines were reported across eastern US. Birds exhibited a range clinical signs including swollen conjunctiva, ocular discharge, ataxia, nystagmus. As part diagnostic investigation, high-throughput metagenomic next-generation sequencing was performed three molecular laboratories on samples from affected birds. Many potentially pathogenic...

10.1101/2023.06.20.545358 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-06-23
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