- Alzheimer's disease research and treatments
- Tea Polyphenols and Effects
- Natural product bioactivities and synthesis
- Neuroinflammation and Neurodegeneration Mechanisms
- Adipose Tissue and Metabolism
- Tannin, Tannase and Anticancer Activities
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Microbial Metabolism and Applications
- Neurological Disease Mechanisms and Treatments
- Algal biology and biofuel production
- Microbial Community Ecology and Physiology
- Adipokines, Inflammation, and Metabolic Diseases
- Aquatic Ecosystems and Phytoplankton Dynamics
- Essential Oils and Antimicrobial Activity
- Identification and Quantification in Food
- Traditional Chinese Medicine Analysis
Chonnam National University
2016-2023
Bacteria are one of the major causes severe infections and diseases plants animals. Salmonella crucially important due to infection in poultry leading huge economical loses. Due high cost microbial resistance currently available chemical antibiotics, demand screening natural products with antibiotics effects is increased. Plants rich sources bioactive compounds antibiotic effects. Saponins plant having a diverse range applications. In present study we investigated vitro vivo antibacterial...
Abstract Amyloid beta (Aβ) aggregation and tau hyper phosphorylation (p-tau) are key molecular factors in Alzheimer’s disease (AD). The abnormal formation accumulation of Aβ p-tau lead to the amyloid plaques neurofibrillary tangles (NFTs) which ultimately leads neuroinflammation neurodegeneration. β- γ-secretases produce peptides via amyloidogenic pathway, several kinases involved phosphorylation. Exosomes, a recently developed method intercellular communication, derived from neuronal stem...
Microcystis aeruginosa , a freshwater microalga, is capable of producing and accumulating different types sugars in its biomass which make it good feedstock for bioethanol production. Present study aims to investigate the effect factors increasing growth rate carbohydrates productivity M. . MF media (modified BG11 media) additional ingredients such as aminolevulinic acid (2 mM), lysine (2.28 alanine (1 Naphthalene acetic mM) cytokine promoted sugar contents. Salmonella showed...
Tauopathy is one of the major causes neurodegenerative disorders and diseases such as Alzheimer’s disease (AD). Hyperphosphorylation tau proteins by various kinases leads to formation PHF NFT eventually results in tauopathy AD; similarly, neuroinflammation also exaggerates accelerates neuropathy neurodegeneration. Natural products with anti-tauopathy anti-neuroinflammatory effects are highly recommended safe feasible ways preventing /or treating diseases, including AD. In present study, we...
Obesity is a public health problem characterized by increased body weight due to abnormal adipose tissue expansion. Bioactive compound consumption from the diet or intake of dietary supplements one possible ways control obesity. Natural products with adipogenesis-regulating potential act as obesity treatments. We evaluated synergistic antiangiogenesis, antiadipogenic and antilipogenic efficacy standardized rebaudioside A, sativoside, theasaponin E1 formulations (RASE1) in vitro human...
Bacteria are among the most common causes of severe diseases in both plants and animals. Salmonella spp. has deleterious effects is cause various transmittable diseases. Because strains resistivity, side high prices synthetic antibiotics, it become essential to explore safe economical natural sources antibiotics. In this study, growth inhibitory antibiotics present crude extracts Galla rhois, Thujae semen, Paeonia japonica, Armeniacae semen were investigated vivo iv vitro. Ethanol...