A5060595668- Atherosclerosis and Cardiovascular Diseases
- Immune cells in cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Mitochondrial Function and Pathology
- Cholesterol and Lipid Metabolism
- Lipoproteins and Cardiovascular Health
- Neuroinflammation and Neurodegeneration Mechanisms
- Autophagy in Disease and Therapy
- Inflammasome and immune disorders
- Cancer, Lipids, and Metabolism
- Phagocytosis and Immune Regulation
- Chemokine receptors and signaling
- Cardiovascular Disease and Adiposity
- interferon and immune responses
- Biomarkers in Disease Mechanisms
- Hydrogen's biological and therapeutic effects
- Cell Adhesion Molecules Research
- Essential Oils and Antimicrobial Activity
- Immune responses and vaccinations
- Cytokine Signaling Pathways and Interactions
- Telomeres, Telomerase, and Senescence
- Cancer, Hypoxia, and Metabolism
- Cancer, Stress, Anesthesia, and Immune Response
- Alzheimer's disease research and treatments
- Organophosphorus compounds synthesis
Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences
2016-2025
Institute of Gene Biology
2018-2025
Engelhardt Institute of Molecular Biology
2024-2025
Russian Scientific Center of Surgery
2023-2024
Russian Academy of Sciences
2024
Genetic Technologies (Australia)
2024
Research Institute of Human Morphology
2021-2023
National Medical Research Center of Cardiology
2018-2022
Institute of Experimental Cardiology
2014-2022
Institute for Atherosclerosis Research
2013-2021
Vessel Plus is an open acccess journal, which publishes articles related to vascular diseases, including acute respiratory distress syndrome, aneurysm, atherosclerosis, hypertension, stroke, peripheral or pulmonary etc.
Rheumatoid arthritis (RA) is a chronic, systemic, and inflammatory autoimmune condition characterized by synovitis, pannus formation (with adjacent bone erosion), joint destruction. In the perpetuation of RA, fibroblast-like synoviocytes (FLSs), macrophages, B cells, CD4
Recent studies have shown that cellular metabolism is tightly linked to the regulation of immune cells. Here, we show activation cholesterol metabolism, involving uptake, synthesis, and autophagy/lipophagy, integral innate responses in macrophages. In particular, accumulation within endosomes lysosomes a hallmark dynamics elicited by Toll-like receptor 4 required for amplification myeloid differentiation primary response 88 (Myd88) signaling. Mechanistically, Myd88 binds via its CLR...
Diabetes is an increasingly prevalent global disease caused by the impairment in insulin production or function. long term causes both microvascular and macrovascular complications that may result retinopathy, nephropathy, neuropathy, peripheral arterial disease, atherosclerotic cardiovascular cerebrovascular disease. Considerable effort has been expended looking at numerous genes pathways to explain mechanisms leading diabetes-related complications. Curcumin a traditional medicine with...
Hair growth is a highly complex process regulated at multiple levels, including molecular pathways, stem cell behavior, metabolic processes, and immune responses. The hair follicle exhibits compartmentalization, with some cells relying on glycolysis others oxidative phosphorylation. Interestingly, in mice, the onset of anagen phase can be stimulated by locally suppressing phosphorylation skin. This study showed that topical application palmitate or oleate accelerated while lactate, end...
A hallmark of atherosclerosis is its complex pathogenesis, which dependent on altered cholesterol metabolism and inflammation. Both arms pathogenesis involve myeloid cells. Monocytes migrating into the arterial walls interact with modified low-density lipoprotein (LDL) particles, accumulate convert foam cells, promote plaque formation also contribute to inflammation by producing proinflammatory cytokines. number studies characterized transcriptomics macrophages following interaction LDL,...
Accumulation of lipid-laden (foam) cells in the arterial wall is known to be earliest step pathogenesis atherosclerosis. There almost no doubt that atherogenic modified low-density lipoproteins (LDL) are main sources accumulating lipids foam cells. Atherogenic LDL taken up by cells, such as macrophages, pericytes, and smooth muscle an unregulated manner bypassing receptor. The present study was conducted reveal possible common mechanisms interaction macrophages with associates non-lipid...