Jules Mérian

ORCID: 0000-0002-2090-5961
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Diet, Metabolism, and Disease
  • Dietary Effects on Health
  • Adipokines, Inflammation, and Metabolic Diseases
  • Adenosine and Purinergic Signaling
  • Lipid metabolism and disorders
  • Alcohol Consumption and Health Effects
  • Pancreatitis Pathology and Treatment
  • Pancreatic function and diabetes
  • Diet and metabolism studies

Université Toulouse III - Paul Sabatier
2023

Institut des Maladies Métaboliques et Cardiovasculaires
2019-2023

Inserm
2019-2023

Université de Toulouse
2019-2023

Paris Cardiovascular Research Center
2019

Université Paris Cité
2019

In humans and animal models, intermittent fasting (IF) interventions promote body weight loss, improve metabolic health, are thought to lower cardiovascular disease risk. However, there is a paucity of reports on the relevance such nutritional in context dyslipidemia atherosclerotic diseases. The present study assessed atheroprotective effects intervention atherosclerosis-prone apolipoprotein E-deficient (Apoe-/-) mice. Groups male female Apoe-/- mice were fed regular (chow) or atherogenic...

10.3390/cells12040533 article EN cc-by Cells 2023-02-07

Nonalcoholic steatohepatitis (NASH) is an emerging health problem worldwide. However, efficacious pharmacological treatment for NASH lacking. A major issue preclinical evaluation of potential therapeutics the limited number appropriate animal models, i.e., models that do not require long-term dietary intervention and adequately mimic disease progression in humans. The present study aimed to evaluate a 3-wk mouse model validate it by studying effects liraglutide, compound advanced clinical...

10.1152/ajpgi.00139.2019 article EN AJP Gastrointestinal and Liver Physiology 2019-08-28

In humans and animal models, intermittent fasting (IF) interventions promote body weight loss, improve metabolic health, are thought to lower cardiovascular disease risk. However, there is a paucity of reports on the relevancy such nutritional in context dyslipidemia atherosclerotic diseases. The present study assessed atheroprotective effects intervention atherosclerosis-prone apolipoprotein E-deficient (Apoe-/-) mice. Groups male female Apoe-/- mice were fed regular (chow) or atherogenic...

10.20944/preprints202301.0160.v1 preprint EN 2023-01-09

ABSTRACT Aim Non-alcoholic steatohepatitis (NASH) is an emerging health problem worldwide. However, efficacious pharmacological treatment for NASH lacking. A major issue preclinical evaluation of potential therapeutics the limited number appropriate animal models, i.e., models that do not require long-term dietary intervention and adequately mimic disease progression in humans. The present study aimed to evaluate a 3-week mouse model validate it by studying effects liraglutide, compound...

10.1101/640854 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2019-05-17
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