A5036258146- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Tracheal and airway disorders
- Tuberous Sclerosis Complex Research
- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Trauma and Emergency Care Studies
- Head and Neck Surgical Oncology
- Pancreatitis Pathology and Treatment
- Anesthesia and Neurotoxicity Research
- Neonatal Respiratory Health Research
- Head and Neck Cancer Studies
- Esophageal and GI Pathology
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Neurofibromatosis and Schwannoma Cases
- Salivary Gland Tumors Diagnosis and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Blood transfusion and management
- PI3K/AKT/mTOR signaling in cancer
- Medical Practices and Rehabilitation
- Disaster Response and Management
- Pancreatic and Hepatic Oncology Research
- Facial Trauma and Fracture Management
University Hospital Cologne
2014-2024
University of Cologne
2019-2024
Poliklinik für Endokrinologie, Diabetologie und Präventivmedizin
2011-2024
Klinikum Region Hannover
2007-2016
Sana Klinikum Lichtenberg
2008-2010
University of Münster
2008
University Hospital Münster
2008
Klinik und Poliklinik für Psychosomatik und Psychotherapie
2007
University of Bonn
2005-2007
Robert Koch Institute
2004-2006
Objective of our study was to determine the agreement between version 1 (v1) and v2 Prostate Imaging Reporting Data System (PI-RADS) for evaluation multiparametric prostate MRI (mpMRI) compare their diagnostic accuracy, inter-observer practicability.mpMRI including T2-weighted imaging, diffusion-weighted imaging (DWI) dynamic contrast-enhanced (DCE) 54 consecutive patients, who subsequently underwent MRI-guided in-bore biopsy were re-analyzed according PI-RADS v1 by two independent readers....
Balloon cells of distinct focal cortical dysplasias type IIb (FCD ) and giant tubers in tuberous sclerosis (TSC) constitute neuropathological hallmarks cytological similarities. In TSC, frequent mutations the TSC1 or TSC2 genes result mTOR‐signaling activity. Here, we addressed whether Pi3K‐pathway activation differentiates balloon from cells. We used immunohistochemistry with antibodies against p ‐PDK1 (S241), ‐Akt (S473), ‐tuberin (T1462), ‐p70 S6K (T389), (T229) phalloidin‐staining to...
Abstract Positive effects of exercise on cancer prevention and progression have been proposed to be mediated by stimulating natural killer (NK) cells. Because NK cell receptors are regulated epigenetic modifications, we investigated whether acute aerobic training change promoter DNA methylation gene expression the activating KIR2DS4 inhibiting KIR3DL1 gene. Sixteen healthy women (50–60 years) performed a graded test (GXT) were randomized into either passive control group or an intervention...
<h3>Background:</h3> The understanding of genetic risk factors for chronic pancreatitis increased in the last decade with discovery mutations cationic trypsinogen gene (<i>PRSS1</i>). first mutation was detected at R122 autocleavage site protein (R122H) and subsequently two other this region, R122C V123M, were described that resulted a similar phenotype hereditary pancreatitis. This study reports novel A121T within region characterises resulting molecular properties site. <h3>Methods:</h3>...
Gangliogliomas and focal cortical dysplasias (FCDs) constitute glioneuronal lesions, which are frequently encountered in biopsy specimens of patients with pharmacoresistant epilepsy relate to impaired differentiation migration neural precursors. However, their molecular pathogenesis relationship still largely enigmatic. Recent data suggest several components the insulin-pathway, including TSC1 TSC2 mutated tuberous sclerosis complex (TSC), be altered gangliogliomas FCD Taylor type balloon...
Cardiopulmonary exercise testing (CPET) objectively informs preoperative risk stratification prior to major surgery. CPET facilities are resource intensive and therefore more cost-effective triage methods desirable for scalability. We tested two dynamic parameters (end-tidal CO<inf>2</inf> (P<inf>et</inf>CO<inf>2</inf>) heart rate (HR)) early phase resting diffusion capacity (DLCO) as potential point of care assessments that could be used outside formal facilities.We conducted a...
IntroductionPrehabilitation is increasingly recognised as a therapeutic option to reduce postoperative complications. Investigating the beneficial effects of exercise on cellular mechanisms, we have previously shown that single episode exhaustive effectively stimulates endothelial progenitor cells (a cell population associated with vascular maintenance, repair, angiogenesis, and neovascularization) in correlation fewer complications, despite ongoing debate about appropriate surface marker...
No AccessJournal of UrologyClinical Urology: Case Report1 May 1997Endoscopic Removal Intravesical Pencils Using Percutaneous Nephrolithotomy Sheath and Forceps Hartmut E.H. Wegner, Michael Franke, Volker Schick WegnerHartmut Wegner More articles by this author , FrankeMichael Franke SchickVolker View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)64878-XAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail...
Parallel to the pilot project of Lee et al. which was published in February 2004, we also considered possibility seal percutaneous nephrolithotomy (PCNL) access after complete stone removal via local amplatz sheath. We started our with aims increasing postoperative patient comfort, minimizing risk bleeding, and reducing cost length hospital stay by performing this minimally invasive technique 7 patients medium burden.All were treated removing stones a working channel passing through lower...
Fragestellung: Parallel zu der Pilotarbeit von Lee u. Mitarb. aus Irvine in Kalifornien [12], hatten auch wir die Überlegung angestellt, perkutanen Nephrolitholapaxiekanäle (PCNL) nach kompletter Steinausräumung über den liegenden Amplatzschaft verkleben. Um durch nephrostomiefreie Operation postoperativen Komfort für Patienten erhöhen, das Blutungsrisiko minimieren und postoperative Kosten Verweilzeit kürzen, starteten unsere Serie mit 7 mittlerer Steinlast (Steindurchmesser ab 2 cm)....