A5017913320- Bacterial Genetics and Biotechnology
- Carbohydrate Chemistry and Synthesis
- Skin Protection and Aging
- Bacteriophages and microbial interactions
- Amino Acid Enzymes and Metabolism
- Legume Nitrogen Fixing Symbiosis
- Dermatology and Skin Diseases
- Olfactory and Sensory Function Studies
- Nail Diseases and Treatments
- Cutaneous lymphoproliferative disorders research
- Antibiotic Resistance in Bacteria
- Enzyme Structure and Function
- Bacterial biofilms and quorum sensing
- Cancer Research and Treatments
- Protist diversity and phylogeny
- Antimicrobial Peptides and Activities
- Gut microbiota and health
- Insect and Pesticide Research
- Contact Dermatitis and Allergies
- Probiotics and Fermented Foods
- Polyamine Metabolism and Applications
- Enzyme Production and Characterization
- melanin and skin pigmentation
- Indoor Air Quality and Microbial Exposure
- Bacterial Identification and Susceptibility Testing
Procter & Gamble (United States)
2004-2021
Chulalongkorn University
2008
University of Guelph
1997-2005
Eli Lilly (United States)
2001
Understanding the changes in skin microbiome and their relationship to host factors during aging remains largely unknown. To better understand this phenomenon, we collected samples for metagenomic factor analyses from forearm, buttock, facial 158 Caucasian females aged 20‒24, 30‒34, 40‒44, 50‒54, 60‒64, 70‒74 years. Metagenomics analysis was performed using 16S ribosomal RNA gene sequencing, whereas sebocyte gland area, lipids, natural moisturizing factors, antimicrobial peptides...
ABSTRACT A noninvasive, real-time detection technology was validated for qualitative and quantitative antimicrobial treatment applications. The lux gene cluster of Photorhabdus luminescens introduced into an Escherichia coli clinical isolate, EC14, on a multicopy plasmid. This bioluminescent reporter bacterium used to study effects in vitro vivo, using the neutropenic-mouse thigh model infection. Bioluminescence monitored measured vivo with intensified charge-coupled device (ICCD) camera...
The Pseudomonas aeruginosa A‐band lipopolysaccharide (LPS) molecule has an O‐polysaccharide region composed of trisaccharide repeat units α1 → 2, 3, 3 linked D ‐rhamnose (Rha). polysaccharide is assembled by the α‐ ‐rhamnosyltransferases, WbpX, WbpY and WbpZ. WbpZ probably transfers first Rha residue onto accepting molecule, while WbpX subsequently transfer two residues one 2 respectively. last transferases are predicted to be processive, alternating in their activities complete polymer....
Pseudomonas aeruginosa coexpresses two distinct lipopolysaccharide (LPS) molecules known as A band and B band. is the serospecific LPS, while common LPS antigen composed of a D-rhamnose O-polysaccharide region. An operon containing eight genes responsible for A-band polysaccharide biosynthesis export has recently been identified characterized (H. L. Rocchetta, Burrows, J. C. Pacan, S. Lam, unpublished data; H. data). In this study, we report characterization within cluster, designated wzm...
Pseudomonas aeruginosa is capable of producing various cell‐surface polysaccharides including alginate, A‐band and B‐band lipopolysaccharides (LPS). The D ‐mannuronic acid residues alginate the ‐rhamnose ( ‐Rha) polysaccharide are both derived from common sugar nucleotide precursor GDP‐ ‐mannose ‐Man). Three genes, rmd , gmd wbpW which encode proteins involved in synthesis ‐Rha, have been localized to 5′ end gene cluster. In this study, WbpW was found be homologous phosphomannose isomerases...
d-Rhamnose is a rare 6-deoxy monosaccharide primarily found in the lipopolysaccharide of pathogenic bacteria, where it involved host-bacterium interactions and establishment infection. The biosynthesis d-rhamnose proceeds through conversion GDP-d-mannose by 4,6-dehydratase (GMD) to GDP-4-keto-6-deoxymannose, which subsequently reduced GDP-d-rhamnose reductase. We have determined crystal structure GMD from Pseudomonas aeruginosa complex with NADPH GDP. belongs NDP-sugar modifying subfamily...
Scalp seborrheic dermatitis and dandruff (SD/D) are chronic conditions requiring long-term treatment. There is a common belief that patients frequently experience decreasing benefits over time when using single product. This physiologic accommodation termed tachyphylaxis.To systematically investigate the anecdotal tachyphylaxis occurs in treatment of SD/D quantitative clinical assessments.An international questionnaire completed by 722 dermatologists assessed incidence with pyrithione zinc...
Summary Background Axillary hair can influence the development of underarm odor in men. Objective To compare different removal procedures and their impact on effectiveness standard soap washing ( SW ) reducing male axillary odor. Methods The axillae healthy Caucasian males N = 30; 18–48 years age) were randomized a noncrossover, split body design. Two four treatments evaluated per subject: clipped with scissors; wet shaved razor; waxed; untreated. Odor evaluations performed by trained...
This article was published in Mol Microbiol (1998) 28(6), 1103–1119. Because of an oversight, the GenBank accession numbers and references for protein sequences used Fig. 6 were not provided. The necessary information concerning these proteins is given below.
Pseudomonas aeruginosa produces two forms of lipopolysaccharide (LPS) designated A band and B band. The O-polysaccharide region is a conserved D-rhamnan polymer arranged α1—2, α1—3, while serotype-specific with differences in the O-antigenic dividing P. into 20 stereotypes. O-antigen unit serotype O5 [—4)-β-D-Man(2NAc3N)A-(1-4)-β-D-Man(2NAc3NAc)A-(1-3)-α-D-Fuc2NAc]. glycosidic structure LPS molecules specified by action dedicated glycosyltransferases. wbp clusters (serotype O5) were each...
This article was published in Mol Microbiol (1998) 29(6), 1419–1434. Because of a problem during typesetting, page 1434 not printed. should have contained the final references for paper and these are reproduced below. May, T.B., Shinabarger, D., Boyd, A., Chakrabarty, A.M. (1994) Identification amino acid residues involved activity phosphomannose isomerase-guanosine 5′-diphospho-D-mannose pyrophosphorylase, bifunctional enzyme alginate biosynthetic pathway Pseudomonas aeruginosa. J Biol...