A5091541693- Skin Protection and Aging
- Dermatology and Skin Diseases
- Gut microbiota and health
- Metabolomics and Mass Spectrometry Studies
- Bayesian Methods and Mixture Models
- Nerve injury and regeneration
- Advanced Proteomics Techniques and Applications
- Bee Products Chemical Analysis
- melanin and skin pigmentation
- Mass Spectrometry Techniques and Applications
- Botulinum Toxin and Related Neurological Disorders
- Neurological diseases and metabolism
- Indoor Air Quality and Microbial Exposure
Procter & Gamble (United States)
2005-2025
Understanding the changes in skin microbiome and their relationship to host factors during aging remains largely unknown. To better understand this phenomenon, we collected samples for metagenomic factor analyses from forearm, buttock, facial 158 Caucasian females aged 20‒24, 30‒34, 40‒44, 50‒54, 60‒64, 70‒74 years. Metagenomics analysis was performed using 16S ribosomal RNA gene sequencing, whereas sebocyte gland area, lipids, natural moisturizing factors, antimicrobial peptides...
Peripheral neuropathy (PN) is a prevalent condition characterized by damage to peripheral nerves, often linked risk factors such as diabetes. This results from various forms of neural damage, including injury the cell body, axons, or demyelination, frequently beginning with small and thinly unmyelinated fibers. Such nerve disrupts normal signaling, leading symptoms like numbness, tingling, pain. Effective repair regeneration, particularly through remyelination, are essential therapeutic...
Dullness or lack of radiance in facial appearance is a common concern among females. Previous studies have linked skin dullness to aging and revealed alterations pigments. However, younger individuals (ages ≤ 35) also report concerns about dull their hectic daily lives, which may not involve pigmentation changes. We hypothesized that the mechanisms underlying youth differ from those associated with aging. To investigate this, we measured cellular molecular changes 132 healthy Japanese...
Many laboratories identify proteins by searching tandem mass spectrometry data against genomic or protein sequence databases. These database searches typically use the measured peptide masses derived and, in this paper, we focus on latter. We study minimum requirements for definitive identification from Accurate measurements are not needed identification, even when a limited amount of is available searching. This information has implications performance (and cost), base search strategies and...