A5082046094- Maternal Mental Health During Pregnancy and Postpartum
- Child and Adolescent Psychosocial and Emotional Development
- Birth, Development, and Health
- Analytical Chemistry and Sensors
- Infant Development and Preterm Care
- Child Abuse and Trauma
- Electrochemical sensors and biosensors
- Retinal Diseases and Treatments
- Pregnancy and preeclampsia studies
- Neuroendocrine regulation and behavior
- Glaucoma and retinal disorders
- Neonatal Respiratory Health Research
- Water Quality Monitoring and Analysis
- Attention Deficit Hyperactivity Disorder
- Cannabis and Cannabinoid Research
- Retinal and Optic Conditions
- Neonatal and fetal brain pathology
- Advanced biosensing and bioanalysis techniques
- Epigenetics and DNA Methylation
- Health and Medical Studies
- Prenatal Substance Exposure Effects
- Migration, Health and Trauma
- Child Nutrition and Feeding Issues
- Family Support in Illness
- Posttraumatic Stress Disorder Research
Hamamatsu University School of Medicine
2019-2025
Icahn School of Medicine at Mount Sinai
2014-2024
Nayoro City University
2024
Queens College, CUNY
2015-2024
The Graduate Center, CUNY
2014-2024
University of Fukui
2022-2023
Kanazawa University
1990-2023
Chiba University
2022-2023
Osaka University
2004-2023
City University of New York
2011-2023
Objective: This study was a 20-year follow-up of offspring depressed and nondepressed parents to determine the magnitude continuity risk parental depression offspring. Method: The authors followed 151 moderately severely or nonpsychiatrically ill comparison subjects for about 20 years, mean age 35 years. Four interviews diagnostic assessments from childhood adolescence adulthood were conducted by assessors blind parents’ clinical status offspring’s previous history. Final best-estimate...
Adolescent depression is highly prevalent and has substantial morbidity, including suicide attempts, school dropout, substance abuse, but many depressed adolescents are untreated. The school-based health clinic offers the potential for accessible efficient treatment, although it unknown whether clinicians can be trained to implement evidence-based psychotherapies in routine care.To assess effectiveness of interpersonal psychotherapy modified (IPT-A) compared with treatment as usual (TAU)...
<h3>Background</h3> The familial nature of early-onset major depressive disorder (MDD) has been documented in numerous family studies adults and is supported by offspring parents with MDD, for whom the risk more than 3-fold. None published high-risk have gone beyond 2 generations, few a longitudinal design. We report results an approximately 20-year follow-up families at high low depression. first generations were interviewed 4 times during this period. from second generation are now...
This study was aimed to assess the diversity of meconium microbiome and determine if bacterial community is affected by maternal diabetes status.The first intestinal discharge (meconium) collected from 23 newborns stratified status: 4 mothers had pre-gestational type 2 mellitus (DM) including one mother with dizygotic twins, 5 developed gestational (GDM) 13 no diabetes. The profiled using multi-barcode 16S rRNA sequencing followed taxonomic assignment analysis.All samples were not sterile...
To evaluate whether conjoined maternal posttraumatic stress disorder (PTSD) and depression are associated with increased behavioral problems among terrorism‐exposed preschool children ( N = 116; 18–54 months), this study compared clinically significant child problem rates the of mothers PTSD depression, alone, neither disorder. Behavioral were independently rated by teachers. Maternal PTSD, relative to disorder, substantially problems. Notably, emotional reactivity (relative risk [RR] 5.9...
Fluorometric detection of O2-• is performed based on desulfonylation 3 to the corresponding fluoresceins 4 through nucleophilic substitution, and this fluorescing process quite specific toward over H2O2, t-BuOOH, NaOCl, 1O2, HO•, NO•, ONOO-. Furthermore, effects glutathione, cytochrome P450 reductase/NADPH, diaphorase/NADH are relatively small probe with X = Y F, which useful detect released from neutrophils stimulated by phorbol myristate acetate satisfactory sensitivity.
The goal of this study was to examine the degree which children born within "normal term" range 37 41 weeks' gestation vary in terms school achievement.This analyzed data from 128050 singleton births between and a large US city. Data were extracted city birth records assess number obstetric, social, economic variables, at both individual community levels. Birth then matched with public standardized city-wide third-grade reading math tests. Specifically, we assessed (1) whether normal term...
Whether the association between higher screen time in infancy and later suboptimal neurodevelopment can be mitigated by frequency of outdoor play is unknown.To investigate whether at age 2 years associated with neurodevelopmental outcomes 4 this mediated 8 months.Participants were a subsample Hamamatsu Birth Cohort Study for Mothers Children (HBC Study, N = 1258). born December 2007 March 2012 followed up from 1 year 6 months to years. The analysis was conducted April 2021 June 2022.Screen...
This study examines the association between trauma exposure and posttraumatic stress disorder (PTSD) among 157 help-seeking children (aged 8-17). Structured clinical interviews are carried out, linear logistic regression analyses conducted to examine relationship PTSD type of controlling for age, gender, ethnicity. Confrontation with traumatic news, witnessing domestic violence, physical abuse, sexual abuse each significantly associated PTSD. Witnessing a crime, being victim accidents, fire,...
The relationship between exposure to the World Trade Center (WTC) attacks, increased substance use, functional impairment and mental health service controlling for depression post‐traumatic stress disorder, was assessed through an in‐school survey of directly exposed students (N = 1040) attending five middle high schools nearest WTC. conducted 18 months after attacks. Students with one WTC risk factor had a five‐fold increase in while those three or more risks nearly 19‐fold increase....
Significance Cannabis use is becoming more prevalent, including during developmentally sensitive periods such as pregnancy. Here we find that maternal cannabis associated with increased cortisol, anxiety, aggression, and hyperactivity in young children. This corresponded widespread reductions immune-related gene expression the placenta which correlated anxiety hyperactivity. Future studies are needed to examine effects of on immune function pregnancy a potential regulatory mechanism shaping...
Objectives: To examine the long-term behavioral consequences of exposure to World Trade Center (WTC) attacks in preschool children and evaluate whether conjoined disaster other traumatic events has additive effects.
Abstract Little is known about whether a mother's psychological state during pregnancy influences her offspring's microbiome. This study examined maternal anxiety, depression, and stress associated with the diversity of meconium microbiome, first internal discharge, in 75 newborns from an existing birth cohort study. The microbiome was profiled using multibarcode16S rRNA sequencing at V3‐V4 hypervariable region followed by taxonomic assignment to green gene 16S references 97% similarity...
Abstract This study examined the effects of in utero exposure to maternal depression and Superstorm Sandy, a hurricane that hit metropolitan New York 2012, on infant temperament at 6 months. Temperament was assessed using Infant Behavior Questionnaire‐Revised. Maternal measured by Edinburgh Postnatal Depression Scale. The main interaction Sandy were multivariable generalized linear model. Results show prenatal associated with lower emotion regulation greater distress. Stratification analyses...
Whether longer screen time in infancy increases risk of neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) and ADHD has long been debated, but no causal relationship between the two remains established. Using ongoing longitudinal cohort data, we found that children 24 to 40 months age, genetic ASD was associated with an increase over time. These data suggest prolonged may not be a cause for NDD, early sign NDDs.
This paper investigates the integration of technical vocabulary in merged language models. We explore knowledge transfer mechanisms involved when combining a general-purpose language-specific model with domain-specific model, focusing on resulting model's comprehension jargon. Our experiments analyze impact this merging process target proficiency handling specialized terminology. present quantitative evaluation performance comparing it that individual constituent The findings offer insights...