A5031017755- Child and Adolescent Psychosocial and Emotional Development
- Maternal Mental Health During Pregnancy and Postpartum
- Stress Responses and Cortisol
- Birth, Development, and Health
- Infant Development and Preterm Care
- Child Abuse and Trauma
- COVID-19 Impact on Reproduction
- Tryptophan and brain disorders
- Early Childhood Education and Development
- Family Support in Illness
- Energy and Environment Impacts
- Attachment and Relationship Dynamics
- Air Quality and Health Impacts
- Functional Brain Connectivity Studies
- Health disparities and outcomes
- Neuroendocrine regulation and behavior
- Infant Health and Development
- Mental Health Research Topics
- Health, Environment, Cognitive Aging
- Psychological and Temporal Perspectives Research
- Disaster Response and Management
- Health and Conflict Studies
- Psychosomatic Disorders and Their Treatments
- Advanced Neuroimaging Techniques and Applications
- Aging and Gerontology Research
Stanford University
2021-2025
Health First
2024
The Graduate Center, CUNY
2017-2020
Queens College, CUNY
2017-2020
City University of New York
2017-2020
John Wiley & Sons (United States)
2019
Michigan State University
2019
Hudson Institute
2019
Icahn School of Medicine at Mount Sinai
2018
Abstract Different dimensions of adversity may affect mental health through distinct neurobiological mechanisms, though current supporting evidence consists largely cross-sectional associations between threat or deprivation and fronto-limbic circuitry. In this exploratory three-wave longitudinal study spanning ages 9–19 years, we examined the experiences unpredictability, threat, with development functional connectivity within three brain networks implicated in psychopathology: salience...
Abstract This study examined the effects of in utero exposure to maternal depression and Superstorm Sandy, a hurricane that hit metropolitan New York 2012, on infant temperament at 6 months. Temperament was assessed using Infant Behavior Questionnaire‐Revised. Maternal measured by Edinburgh Postnatal Depression Scale. The main interaction Sandy were multivariable generalized linear model. Results show prenatal associated with lower emotion regulation greater distress. Stratification analyses...
As the global climate crisis persists, it becomes increasingly important to understand how exposure environmental toxins can affect developing brain. Although researchers are beginning document links between prenatal air pollution and brain structure, is not clear when these associations emerge. We leveraged data from GUSTO (Growing Up Toward Healthy Outcomes in Singapore) longitudinal birth cohort study examine development during childhood. Spatiotemporally interpolated particulate matter...
Abstract Exposure to adversity during the perinatal period has been associated with cognitive difficulties in children. Given role of nucleus accumbens (NAcc) attention and impulsivity, we examined whether NAcc volume at age six mediates relations between pre- postnatal subsequent problems offspring. 306 pregnant women were recruited as part Growing Up Singapore Towards Healthy Outcomes Study. Psychosocial stress was assessed pregnancy across first 5 years postpartum. At age, children...
Parenting behaviors and neighborhood environment influence the development of adolescents' brains behaviors. Simultaneous trajectories brain behavior, however, are understudied, especially in these environmental contexts. In this four-wave study spanning 9-18 years age (N=224 at baseline, N=138 final assessment) we used longitudinal k-means clustering to identify clusters participants with distinct uncinate fasciculus (UF) fractional anisotropy (FA) anxiety symptoms; examined behavioral...
Prenatal maternal stress increases the risk for negative developmental outcomes in offspring; however, underlying biological mechanisms remain largely unexplored. In present study, alterations placental gene expression associated with were examined to clarify potential epi/genetic mechanisms. Expression levels of 40 selected genes involved regulating foetal hypothalamic-pituitary-adrenal axis and neurodevelopment profiled tissues collected from a birth cohort established around time...
Mental and physical health are affected by family neighborhood socioeconomic status (SES). Accelerated maturation in the context of lower SES is one mechanism that might contribute to underlying disparities; few studies, however, have considered relation putative markers brain adolescents.In 120 adolescents 13 18 years age, we examined cortical thickness adjusted for age. We also whether was related depressive symptoms explored regions interest.Controlling disadvantage associated with a...
Abstract Researchers have begun to examine the psychological toll of ongoing global COVID-19 pandemic. Data are now emerging indicating that there may be long-term adverse effects pandemic on new mothers and children born during this period. In a longitudinal study maternal mental health child emotional development pandemic, we conducted online assessments cohort women at two time points: when they were pregnant beginning surge in United States (baseline, N = 725), approximately 1 year...
Abstract The placenta adapts to maternal environment and its alterations may have a lasting impact on child's temperament development. Prenatal stress has been linked both downregulation of monoamine oxidase A (MAOA) gene expression in the difficult temperament. Capitalizing an ongoing longitudinal study, we analysed data from 95 mother–child dyads investigate whether MAOA mediates association between prenatal infant was defined as exposure Superstorm Sandy (Sandy) during pregnancy. Infant...
Although the intergenerational transmission of risk for depression is well documented, mechanisms and moderators involved in this from depressed parents to their offspring are not clear. In review, we discuss progress that has been made over past two decades studying describe maladaptive characteristics these a diverse range domains, including clinical, cognitive, biological functioning. Despite recent advances area, there unresolved questions warrant further investigation involving nature...
The field of developmental psychopathology has grown exponentially over the past decades, and become increasingly multifaceted. initial focus on understanding abnormal child psychology broadened to study origins psychopathology, with goals preventing alleviating disorder promoting healthy development. In this paper, we discuss how technological advances global events have expanded questions that researchers in can address. We do so by describing a longitudinal been conducting for dozen...
Maternal stress during pregnancy exerts long-term effects on the mental well-being of offspring. However, effect prenatal exposure offspring's status is only partially understood. The placenta plays a vital role in connecting maternal side to fetus, thereby serving as an important interface between and fetal development. Here, we profiled placental transcriptome women who were pregnant hurricane (Superstorm Sandy), which struck New York City 2012. offspring followed longitudinally their...
Exposure to environmental pollutants has been associated with cellular aging in children and adolescents. Individuals may vary, however, their sensitivity or vulnerability the effects of pollutants. Larger hippocampal volume emerged as a potential index increased social contexts. In exploratory analyses (N = 214), we extend work this area by providing evidence that larger early adolescence reflects effect neighborhood pollution burden on telomere length (standardized β –0.40, 95% CI[–0.65,...
Adolescence is often characterized by sleep disturbances that can affect the development of white matter tracts implicated in affective and cognitive regulation, including cingulate portion cingulum bundle (CGC) uncinate fasciculus (UF). These effects may be exacerbated adolescents exposed to early life adversity (ELA). We examined longitudinal relations between problems CGC UF microstructure during adolescence their relation depressive symptoms as a function exposure ELA. assessed...
Crying is an attachment behavior that functions to elicit support from others (Nelson, 1998); the context in which crying occurs important understanding whether it adaptive or maladaptive (Hendriks & Vingerhoets, 2006). However, very little research has examined and how style associated with adult crying, if this association might vary by individual’s relationship status. Using a sample of 305 first-year college students series hierarchical regressions, we moderating effect status on...
Background Understanding the prenatal origins of children's psychopathology is a fundamental goal in developmental and clinical science. Recent research suggests that inflammation during pregnancy can trigger cascade fetal programming changes contribute to vulnerability for emergence psychopathology. Most studies, however, have focused on handful proinflammatory cytokines not explored range biological pathways may be involved increasing postnatal risk emotional behavioral difficulties....