- Maternal Mental Health During Pregnancy and Postpartum
- Child and Adolescent Psychosocial and Emotional Development
- Child Development and Digital Technology
- Birth, Development, and Health
- Child Nutrition and Feeding Issues
- Autism Spectrum Disorder Research
- Functional Brain Connectivity Studies
- Infant Development and Preterm Care
- Diabetes Management and Research
- Diabetes and associated disorders
- Health and Lifestyle Studies
- Family and Disability Support Research
- Health, Environment, Cognitive Aging
- Cognitive Abilities and Testing
- Impact of Technology on Adolescents
- Psychological Well-being and Life Satisfaction
- Health disparities and outcomes
- Genetics and Neurodevelopmental Disorders
- Attention Deficit Hyperactivity Disorder
- Children's Physical and Motor Development
- Breastfeeding Practices and Influences
- Early Childhood Education and Development
- Obesity, Physical Activity, Diet
- Prenatal Substance Exposure Effects
- Dental Health and Care Utilization
National University Hospital
2019-2025
National University of Singapore
2016-2025
Agency for Science, Technology and Research
2018-2025
Singapore Institute for Clinical Sciences
2018-2025
National University Health System
2016-2025
University Health System
2016-2025
Institute for Human Development
2024
Cedars-Sinai Medical Center
2024
Khoo Teck Puat Hospital
2022
University of California, Irvine Medical Center
2022
Importance Research evidence is mounting for the association between infant screen use and negative cognitive outcomes related to attention executive functions. The nature, timing, persistence of time exposure on neural functions are currently unknown. Electroencephalography (EEG) permits elucidation correlates associated with impairments. Objective To examine associations time, EEG markers, school-age using mediation analysis structural equation modeling. Design, Setting, Participants This...
Abstract Background Screen time in infancy is linked to changes social-emotional development but the pathway underlying this association remains unknown. We aim provide mechanistic insights into using brain network topology and examine potential role of parent–child reading mitigating effects screen time. Methods examined on linear regression analysis tested if mediated between later socio-emotional competence. Lastly, we was a moderator link topology. Results Infant significantly associated...
The goals of this study were (1) to provide estimates diagnostic stability for a sample young children diagnosed with attention-deficit/hyperactivity disorder (ADHD) after undergoing comprehensive multidisciplinary assessments and (2) identify baseline child family characteristics that predict over time.Children aged 3 6 years, 11 months consecutively ADHD consultations at tertiary care clinic between 2003 2008 recontacted in 2012 2013 (N = 120). At follow-up, the primary outcome was...
Despite the potential for COVID-19 infection control-related events to have an effect on child well-being, comprehensive assessments of postlockdown changes and persistent outcomes are lacking.
Background Adjusting to new or additional parenting responsibilities increases stress and affects parental well-being. Existing research has highlighted both parents’ desire receive more support. It also been found that receiving sufficient social support enhances outcomes. With the increasing popularity of mobile health apps, a Supportive Parenting App (SPA) intervention was developed fulfill needs parents during perinatal period. Objective This study aimed examine effectiveness SPA on...
The associations of screen use with children's cognition are not well evidenced and recent, large, longitudinal studies needed. We aimed to assess the between cognitive development in French nationwide birth cohort.
Brain age has emerged as a powerful tool to understand neuroanatomical aging and its link health outcomes like cognition. However, there remains lack of studies investigating the rate brain relationship Furthermore, most models are trained tested on cross-sectional data from primarily Caucasian, adult participants. It is thus unclear how well these generalize non-Caucasian participants, especially children. Here, we previously published deep learning model Singaporean elderly participants...
ABSTRACT Maternal antenatal mood is associated with negative infant temperament. This link has not been substantiated in Asian populations. We evaluated the association between maternal and temperament among mother–infant pairs. Antenatal depression anxiety were assessed using Edinburgh Postnatal Depression Scale (J. Cox, J. Holden, & R. Sagovsky, 1987) State‐Trait Anxiety Inventory (C. Spielberger, Gorsuch, Lushene, P. Vagg, G. Jacobs, 1983), respectively, at 26 weeks of pregnancy 3...
Although infant media exposure has received attention for its implications on child development, upstream risk factors contributing to have rarely been explored. The study aim was examine the relationship between maternal factors, television (TV) viewing, and later cognition. We used a prospective population-based birth cohort study, Growing Up in Singapore Towards healthy Outcomes (GUSTO), with 1247 pregnant mothers recruited their first trimester. explored of TV at 12 months composite IQ...
ABSTRACT: Objective: Screen time in early childhood has been associated with children's prosocial and behavioral skills; however, the directionality of this relationship is unclear. We aimed to determine direction between screen time, social skills, nonsocial traits young children. Methods: This was a population-based, prospective cohort study data across 5 points. examined reciprocal relationships caregiver-reported at 12, 18, 24, 36, 54 months behaviors collected using Infant-Toddler...
The transition to parenthood can be challenging, and parents are vulnerable psychological disorders during the perinatal period. This may have adverse long-term consequences on a child's development. Given rise in technology parents' preferences for mobile health apps, supportive intervention is optimal. However, there lack of theoretical framework technology-based educational couples with healthy infants.The aim this study describe Supportive Parenting App (SPA) development procedure...
Background: Oral care activities, e.g., toothbrushing, are habitual occupations often considered routine. However, for autistic children, performing these routine dental practices can be challenging due to the child’s sensory sensitivities, unique executive function, and complicated way in which children conceptualize structure habits. Limited research exists exploring nuances of oral routines population, more knowledge is needed support targeted education interventions improve address...
Abstract Aims and objectives To explore the perspectives of parents during perinatal period amid COVID‐19 pandemic experiences Singaporean receiving support via Supportive Parenting App (SPA). Background The stressors accompanying parenting responsibilities often affect overall well‐being family unit. With emergence pandemic, are forced to shoulder childcare with minimal due safety restrictions. Application (SPA) was introduced start offer timely additional support. It is a mobile health...
Aim Children with developmental disabilities are at risk of excessive screen time and more vulnerable to sleep problems. The aim this study was determine the extent use in children its relationship duration. Methods Consecutive aged 6–15 years diagnosed Diagnostic Statistical Manual Mental Disorders, Fourth or Fifth Edition (DSM‐IV DSM‐5) were recruited for from December 2014 April 2015. Of those recruited, 87.0% families gave consent provided questionnaire information on demographics...
While socioeconomic position (SEP) is consistently related to pregnancy and birth outcome disparities, relevant biological mechanisms are manifold, thus necessitating more comprehensive characterization of SEP-exposome associations during pregnancy.We implemented an exposomic approach systematically characterize the landscape prenatal exposures in a setting where social segregation was less distinct hypotheses-generating manner.We described correlation structure 134 exogenous endogenous...
Abstract Aims There is compelling evidence for gradient effects of household income on school readiness. Potential mechanisms are described, yet the growth curve trajectory maternal mental health in a child's early life has not been thoroughly investigated. We aimed to examine relationships between incomes, trajectories from antenatal postnatal period, and Methods Prospective data 505 mother–child dyads birth cohort Singapore were used, including income, repeated measures pregnancy 2-years...
Brain age has emerged as a powerful tool to understand neuroanatomical aging and its link health outcomes like cognition. However, there remains lack of studies investigating the rate brain relationship Furthermore, most models are trained tested on cross-sectional data from primarily Caucasian, adult participants. It is thus unclear how well these generalize non-Caucasian participants, especially children. Here, we previously published deep learning model Singaporean elderly participants...