- Functional Brain Connectivity Studies
- Child Development and Digital Technology
- Neonatal and fetal brain pathology
- Stress Responses and Cortisol
- Multilingual Education and Policy
- Neural and Behavioral Psychology Studies
- Health, Environment, Cognitive Aging
- Maternal Mental Health During Pregnancy and Postpartum
- Infant Development and Preterm Care
- Child and Adolescent Psychosocial and Emotional Development
- Prenatal Substance Exposure Effects
- Impact of Technology on Adolescents
- Neural dynamics and brain function
- Child Abuse and Trauma
Singapore Institute for Clinical Sciences
2022-2024
Agency for Science, Technology and Research
2022-2024
Importance Research evidence is mounting for the association between infant screen use and negative cognitive outcomes related to attention executive functions. The nature, timing, persistence of time exposure on neural functions are currently unknown. Electroencephalography (EEG) permits elucidation correlates associated with impairments. Objective To examine associations time, EEG markers, school-age using mediation analysis structural equation modeling. Design, Setting, Participants This...
Abstract Early-life adversity (ELA) exposure is suggested to accelerate development. However, the influence of ELA on neurodevelopmental trajectories has not been assessed directly but largely inferred from retrospective reporting in adult cohorts. Using multimodal neuroimaging data a pediatric cohort study ( N = 549), we modeled over childhood with structure–function coupling (SC–FC), correlation between structural and functional connectivity. A linear decrease SC–FC was observed age 4.5...
Abstract Background Screen time in infancy is linked to changes social-emotional development but the pathway underlying this association remains unknown. We aim provide mechanistic insights into using brain network topology and examine potential role of parent–child reading mitigating effects screen time. Methods examined on linear regression analysis tested if mediated between later socio-emotional competence. Lastly, we was a moderator link topology. Results Infant significantly associated...
Early differences in reward behavior have been linked to executive functioning development. The nucleus accumbens (NAc) and orbitofrontal cortex (OFC) are activated by reward-related tasks identified as key nodes of the brain circuit that underlie processing. We aimed investigate relation between NAc-OFC structural functional connectivity preschool children, well associations with future sensitivity function. showed were not significantly associated but both independently predicted males a...
Excessive screen time utilization in childhood has been linked to executive dysfunction. Our primary aim was investigate the potential influence of early on brain network topology and later function (EF). We collected data (between ages 0-4 years) (n = 950), followed by MRI at age 6 414) assessment 7 620). Screen significantly associated with emotion processing-cognitive control integration which mediates effect EF performance.