A5031749982- Gestational Diabetes Research and Management
- Hemophilia Treatment and Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Blood Coagulation and Thrombosis Mechanisms
- Platelet Disorders and Treatments
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
- Mobile Health and mHealth Applications
- Maternal Mental Health During Pregnancy and Postpartum
- Birth, Development, and Health
- Bariatric Surgery and Outcomes
- Assisted Reproductive Technology and Twin Pregnancy
- Breastfeeding Practices and Influences
- Endometriosis Research and Treatment
- Prenatal Screening and Diagnostics
- Uterine Myomas and Treatments
- Maternal and Perinatal Health Interventions
- Prenatal Substance Exposure Effects
- Parvovirus B19 Infection Studies
- Obesity, Physical Activity, Diet
- Eating Disorders and Behaviors
- Cardiovascular Issues in Pregnancy
- Pregnancy-related medical research
- Child Nutrition and Feeding Issues
- Gynecological conditions and treatments
National University Hospital
2016-2022
National University Health System
2014-2020
National University of Singapore
2015-2020
The Royal Free Hospital
2006-2013
University College London
2006-2013
RELX Group (United States)
2011
RELX Group (United Kingdom)
2011
OBJECTIVE SMART-GDM examined whether Habits-GDM, a smartphone application (app) coaching program, can prevent excessive gestational weight gain (EGWG) and improve glycemic control maternal neonatal outcomes in diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS In this randomized controlled trial, women diagnosed with GDM between 12 30 weeks were randomly assigned to usual care (control) or additional support from Habits-GDM that integrated dietary, physical activity, weight, glucose...
The aim of the study was to review complications, management and outcome pregnancy in carriers haemophilia over a 10-year period following introduction multidisciplinary guideline. Comparison made cohort prior implementation guidelines. A retrospective case notes (41 A, 12 B) who had received obstetric care at Royal Free Hospital between 1995 2005 conducted. There were 90 pregnancies (65 live births, 13 miscarriages, terminations). Prenatal testing taken up 97% (63/65) where mother known be...
OBJECTIVE Better preconception metabolic and nutritional health are hypothesized to promote gestational normoglycemia reduce preterm birth, but evidence supporting improved outcomes with supplementation starting is limited. RESEARCH DESIGN AND METHODS This double-blind randomized controlled trial recruited from the community 1,729 U.K., Singapore, New Zealand women aged 18–38 years planning conception. We investigated whether a formulation containing myo-inositol, probiotics, multiple...
A retrospective review was carried out on the methods of obstetric analgesia/anesthesia used in 80 pregnancies amongst 63 women with inherited bleeding disorders (19 factor XI deficiency, 16 carriers haemophilia, 15 von Willebrand disease, seven platelet function disorders, four VII one and deficiency X deficiency). In 72 pregnancies, woman seen antenatally a multidisciplinary clinic to discuss plan pain relief options. Regional block performed for 41 pregnancies. The mothers were known have...
Are higher overall and central adiposity associated with reduced fecundability, measured by time-to-pregnancy (TTP), in Asian women? Higher adiposity, but not was longer TTP women. High body mass index (BMI) has been a TTP, although the associations of composition distribution are less clear. There no previous studies women, who have relatively percentage fat abdominal at lower BMI. Prospective preconception cohort using data from 477 (Chinese, Malay Indian) women were planning to conceive...
Iron deficiency is the most prevalent nutrient and common cause of anaemia worldwide. Because increased iron requirements during pregnancy, can lead to maternal reduced newborn stores. We examined proportion risk factors among pregnant women in a developed Asian country. Within prospective cohort Singapore, 985 were assessed for status at 26–28 weeks' gestation, with plasma ferritin soluble transferrin receptor (sTfR) measurements. was determined according concentrations ≥30 μg/L (iron...
Mobile apps are becoming an increasingly ubiquitous platform for delivery of health behavior interventions among overweight and obese perinatal women. However, only a few methodological guidelines on integrating theory, evidence, qualitative research their designs available.The aim this study was to develop theory-based, evidence-driven, user-centered healthy lifestyle app targeting multiethnic pregnant women.This paper illustrates how intervention development may be enriched with...
Ten carriers of haemophilia referred for prenatal diagnosis were offered first trimester non‐invasive fetal gender determination by ultrasound and analysis free DNA (ffDNA) in maternal plasma an attempt to reduce the need invasive diagnostic procedure female pregnancies. Although repeat testing was required three cases, determined correctly all cases (four females, six males) at a median gestation 12 +3 (11 +2 14 +1 ) using both methods. In fetus, mothers opted not have testing. Both methods...
OBJECTIVES. To assess the obstetric outcome in women with factor XI (FXI) deficiency. DESIGN. Retrospective review of medical records. SETTING. Tertiary referral university hospital. POPULATION. Women FXI METHOD. Review pregnancies over a 10-year period (1997-2006). Main measures. Pregnancy outcome, mode delivery, changes levels during pregnancy, use prophylaxis labor and antepartum hemorrhage, postpartum hemorrhage (PPH). RESULTS. There were 61 among 30 deficiency (two severe, level <15-20...
Heart failure (HF) poses a heavy burden on patients, their families and society. The syndrome of HF comes in two types: with reduced ejection fraction (HFrEF) preserved (HFpEF). latter is the increase predominantly present women, especially older ones. There an urgent need for mortality-reducing drugs HFpEF, disease affecting around 5 % those aged 65 years over. HFpEF develops patients risk factors comorbidities such as obesity, hypertension, diabetes, COPD, but also preeclampsia. These...
We assessed the impact of adopting 2013 World Health Organization (WHO) diagnostic criteria on rates gestational diabetes (GDM), pregnancy outcomes and identification women at future risk type 2 diabetes. During a period when 1999 WHO GDM were in effect, pregnant universally screened using one-step 75 g 2-h oral glucose tolerance test 26–28 weeks' gestation. Women retrospectively reclassified according to criteria, but without 1-h glycaemia measurement. Pregnancy 4–5 years post-delivery...
Gestational diabetes mellitus (GDM) is associated with risks for both the mother and child. The escalated prevalence of GDM because obesity changes in screening criteria demands greater health care needs than before.This study aimed to understand perception patients providers barriers management preferred interventions manage an Asian setting.This mixed methods used a convergent parallel design. Survey data were collected from 216 women GDM, semistructured interviews conducted 15 8 treating...
Summary. A mail survey of members and fellows Royal College Obstetricians Gynaecologists was carried out to determine current practices obstetricians gynaecologists in the United Kingdom management women with inherited bleeding disorders. In total, 3929 questionnaires were sent, 707 returned analysis limited 545 valid questionnaires. past 5 years, 91% have managed The majority (83%) considered disorders be under diagnosed obstetrics gynaecology. More than 80% prevalence von Willebrand's...