A5005598334- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Acute Ischemic Stroke Management
- COVID-19 and healthcare impacts
- Retinal and Optic Conditions
- Emergency and Acute Care Studies
- Chronic Disease Management Strategies
- Respiratory viral infections research
- Geriatric Care and Nursing Homes
- Heart Failure Treatment and Management
- Mental Health and Patient Involvement
- Bone health and osteoporosis research
- Sepsis Diagnosis and Treatment
- COVID-19 epidemiological studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetes Management and Research
- HIV Research and Treatment
- Cancer-related gene regulation
- Healthcare professionals’ stress and burnout
- Viral Infections and Vectors
- vaccines and immunoinformatics approaches
- Burn Injury Management and Outcomes
- Workplace Health and Well-being
University of Massachusetts Chan Medical School
2025
University of Missouri
2019-2024
University of Missouri Hospital
2016-2021
The University of Texas Health Science Center at Houston
2019
Background and Purpose: Acute ischemic stroke may occur in patients with coronavirus disease 2019 (COVID-19), but risk factors, in-hospital events, outcomes are not well studied large cohorts. We identified comorbidities, COVID-19 or without acute compared stroke. Methods: analyzed the data from 54 health care facilities using Cerner deidentified dataset. The dataset included an emergency department inpatient encounter discharge diagnoses codes that could be associated to suspicion of...
A better understanding of reinfection after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become one the healthcare priorities in current pandemic. We determined rate reinfection, associated factors, and mortality during follow-up a cohort patients with SARS-CoV-2 infection.We analyzed 9119 who received serial tests total 62 facilities United States between 1 December 2019 13 November 2020. Reinfection was defined by positive separated interval >90 days...
Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are two serious, preventable complications of diabetes mellitus. Analysis variables associated with recurrent DKA HHS admission has the potential to improve patient outcomes by identifying possible areas for intervention. The aim this study was evaluate predictors or admission.This a retrospective case-control 367 patients presenting during 5-year period at US tertiary academic medical center. Six readmission risk factors...
Case series without control groups suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may result in cognitive deficits and dementia the postinfectious period.Adult pneumonia patients with SARS-CoV-2 (index hospitalization) age-, gender-, race/ethnicity-matched contemporary were identified from 110 healthcare facilities United States. The risk of new diagnosis following >30 days after index hospitalization event any previous history was using logistic...
Introduction Islatravir (ISL) is a nucleoside reverse transcriptase translocation inhibitor (NRTTI) that inhibits HIV RT through multiple mechanisms. Contrary to all approved NtRTIs, islatravir retains 3'OH group. In vitro and clinical data show ISL an ultrapotent investigational drug with high tolerability.
Background Existing readmission reduction solutions tend to focus on complementing inpatient care with enhanced transition and postdischarge interventions. These are initiated near or after discharge, when clinicians’ impact is ending. Preventive intervention during hospitalization an underexplored area that holds potential for reducing risk. However, it challenging predict risk at the early stage of because few data available. Objective The objective this study was build prediction model...
Objectives: Acute ischemic stroke patients are at risk of acute kidney injury due to volume depletion, contrast exposure, and preexisting comorbid diseases. We determined the occurrence rate identified predictors associated with in patients. Setting: Multiple specialized ICUs within academic medical centers. Design: Post hoc analysis pooled data from prospective randomized clinical trials. Patients: recruited 3 hours or 5 symptom onset. Interventions: IV recombinant tissue plasminogen...
Objective: To identify differences in short-term outcomes of patients with coronavirus disease 2019 (COVID-19) according to various racial/ethnic groups.Design: Analysis Cerner de-identified COVID-19 dataset.Setting: A total 62 health care facilities.Participants: The cohort included 49,277 adult who were hospitalized from December 1, November 13, 2020.Methods: We compared patients’ age, gender, individual components Charlson and Elixhauser comorbidities, medical complications, use...
An adult male from Missouri sought care for fever, fatigue, and gastrointestinal symptoms. He had leukopenia thrombocytopenia was treated a presumed tickborne illness. His condition deteriorated with respiratory renal failure, lactic acidosis, hypotension. Next-generation sequencing phylogenetic analysis identified reassortant Cache Valley virus.
Abstract Participant representation, including the Good Participatory Practice guidelines, in design and execution of clinical research can profoundly affect structure process. Early COVID-19 pandemic, an online registry called Healthcare Worker Exposure Response Outcomes (HERO) Registry, was launched to capture experiences healthcare workers (HCWs) on pandemic frontlines. It evolved into a program that distributed COVID-19-related information connected participants with opportunities....
Acute ischemic stroke patients with severe acute respiratory syndrome coronavirus maybe candidates for revascularization treatments (intravenous thrombolysis and/or mechanical thrombectomy).
Coronary artery disease (CAD) and osteoporosis, the two most frequently occurring chronic diseases of aging populations, share many risk factors including lack estrogen, smoking, low physical activity. CAD bone mineral density (BMD) are strongly associated. Statins, (3-hydroxy-3-methylglutaryl coenzyme A [HMG-CoA] reductase inhibitors), used to prevent treat have been associated with high BMD. This cross-sectional study examined associations BMD statin use nonuse in elderly women or without...
Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may have an increased risk of cardiovascular events in the convalescent period.To determine whether patients SARS-CoV-2 during period.We analyzed 10,691 hospitalized adult pneumonia and contemporary matched controls without infection. The new following >30 days admission (convalescent period) was ascertained using Cox proportional hazards regression analysis to adjust for potential confounders.Among...
<sec> <title>BACKGROUND</title> Existing readmission reduction solutions tend to focus on complementing inpatient care with enhanced transition and postdischarge interventions. These are initiated near or after discharge, when clinicians’ impact is ending. Preventive intervention during hospitalization an underexplored area that holds potential for reducing risk. However, it challenging predict risk at the early stage of because few data available. </sec> <title>OBJECTIVE</title> The...
Objectives: Acute ischemic stroke patients with severe acute respiratory syndrome coronavirus maybe candidates for revascularization treatments (intravenous thrombolysis and/or mechanical thrombectomy). Materials and Methods: We analyzed the data from 62 healthcare facilities to determine odds of receiving in infected composite death non-routine discharge non-infected undergoing after adjusting potential confounders. Results: infection were significantly less likely receive (odds ratio 0.6,...

 Since December 2019, COVID 19 pandemic has devastated communities across the world. As number of patients recovered from continue to rise, question acquired immunity versus chances re-infection becomes critical understand future spread infection. Here, we present a case patient previously COVID-19, develops new symptoms concerning for possible with positive reverse transcriptase-polymerase chain reaction (RT-PCR) after few months initial infection.