A5000253316- AI in cancer detection
- Digital Radiography and Breast Imaging
- Radiomics and Machine Learning in Medical Imaging
- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Infrared Thermography in Medicine
- Medical Imaging Techniques and Applications
- Phytochemicals and Antioxidant Activities
- Cancer Genomics and Diagnostics
- Molecular Biology Techniques and Applications
- Image Retrieval and Classification Techniques
- Immunodeficiency and Autoimmune Disorders
- COVID-19 Clinical Research Studies
- Fetal and Pediatric Neurological Disorders
- Prenatal Screening and Diagnostics
- Electrochemical sensors and biosensors
- MRI in cancer diagnosis
- Biosensors and Analytical Detection
- Tuberculosis Research and Epidemiology
- Plant chemical constituents analysis
- vaccines and immunoinformatics approaches
- Porphyrin and Phthalocyanine Chemistry
- Biochemical and biochemical processes
- Advanced biosensing and bioanalysis techniques
- Essential Oils and Antimicrobial Activity
Southern Medical University
2019-2024
Nanfang Hospital
2021-2024
Guangdong Pharmaceutical University
2023
Nanjing University
2018-2019
Wenzhou Medical University
2015
<sec>Background<p> Previous studies predominantly reported that the occurrence of hypomagnesemia was associated with improved cancer prognoses. However, utilizing publicly available data, we demonstrated presence bias in this association, attributable to failure account for immortal time (ITB) when grouping patients based on post-therapeutic characteristics/variates. </p></sec><sec>Methods<p> This research included 4,172 individuals from four clinical...
DNA walkers from monopodial to multipedal types have usually one cleavage site power the walking system along with track. Herein, a walker (m-DNA walker) multiple DNAzyme cores was constructed assistance of rolling circle amplification (RCA) for highly sensitive electrochemical biosensing. Firstly, three-component complex as swing strand prepared by integrating padlock, an RCA primer and block recognition element in system. After ferrocene-labeled track (trDNA) capture were fixed on gold...
Abstract Objectives To investigate the imaging characteristics and clinicopathological features of rim enhancement breast masses demonstrated on contrast-enhanced mammography (CEM). Methods 67 cases lesions confirmed by pathology showing CEM examinations were analyzed. The divided into benign malignant groups, morphological enhanced described. Sensitivity, specificity, positive predictive value (PPV), negative (NPV) calculated separately for each morphology descriptor to evaluate diagnostic...
In 2020, breast cancer becomes the most leading diagnosed all over world. The burden is increasing in prevention and treatment of cancer. Accurately detecting lesions screening images important for early detection Architectural distortion (AD) one that need to be detected.To develop a deep-learning-based computer-aided (CADe) model AD digital tomosynthesis (DBT). This uses superior-inferior directional context DBT anatomic prior knowledge reduce false positive (FP). It can identify some...
Objective. In digital breast tomosynthesis (DBT), architectural distortion (AD) is a lesion that difficult to detect. Compared with typical ADs, which have radial patterns, identifying ADs more difficult. Most existing computer-aided detection (CADe) models focus on the of ADs. This study focuses atypical and develops deep learning-based CADe model an adaptive receptive field in DBT.Approach. Our proposed uses Gabor filter convergence measure depict distribution fibroglandular tissues DBT...
This study conducted a comparative analysis of the extraction efficiency and antioxidant potential caffeoylquinic acids (CQAs) from Blumea aromatica using deep eutectic solvents (DESs) traditional solvents. Utilizing UPLC-Q-Orbitrap HRMS, quantification seven CQAs revealed concentrations ranging 0.46 to 7.60 mg/g, with 1,5-diCQA identified as most abundant. DESs demonstrated significant advantages (P < 0.05) over The optimal occurred DES-6 (choline chloride / 1,4-butanediol) for 3-CQA (4.71...
The electrochemical reduction of nitric oxide (NO) catalyzed by metal porphyrins as enzyme mimics provides a promising way to understand its roles in biological denitrification. Here, stepwise electrocatalytic NO was demonstrated cationic picket-fence porphyrin incorporated an ultrathin phospholipid film. mass transport-corrected Tafel slopes −117 mV/dec and −60 for the first second at physiological pH (pH 7.0), respectively, suggesting distinguish mechanism two-step NO. More significantly,...
With the widely application of liquid biopsy and development detection technology, standardization pre-analysis procedures is necessary. For controlling variation circulating tumor DNA (ctDNA) in blood samples, collection tubes for ctDNA preservation particularly contribute a lot. The objective this study was to investigate whether ImproGene® Cell Free Tube (ImproGene tube) can be used sample collection, NGS based mutation ctDNA. We investigated hemolysis cell free (cfDNA) concentration...
Radiologists' diagnostic capabilities for breast mass lesions depend on their experience. Junior radiologists may underestimate or overestimate Breast Imaging Reporting and Data System (BI-RADS) categories of owing to a lack The computer-aided diagnosis (CAD) method assists in improving performance by providing classification reference radiologists. This study aims evaluate the impact CAD based perceptive features learned from quantitative BI-RADS descriptions performance. We conducted...
Automatically matching corresponding regions of interest (ROIs) on two-view images is valuable in breast cancer diagnosis, benefiting saving time and cutting the workload. We propose a method for ROIs by integrating geometric model image similarity searching. The implemented restoring free 3D space from preprocessed contours. Then, possible position ROI center cranio-caudal (CC)/medio-lateral oblique (MLO) view represented three feature points space. As changes, these can be mapped onto...
Objective To assess the diagnostic performance of FFDM-based and DBT-based radiomics models to differentiate breast phyllodes tumors from fibroadenomas. Methods 192 patients (93 99 fibroadenomas) who underwent mammography were retrospectively enrolled. Radiomic features respectively extracted FFDM clearest slice DBT images. A least absolute shrinkage selection operator (LASSO) regression was used select features. combined model constructed by radiological signatures. Machine learning...
To investigate the capability of morphological and enhancement pattern analysis in contrast-enhanced mammography (CEM) to differentiate between benign malignant papillary breast lesions.
Architectural distortion (AD) is one of the important breast abnormal signs in digital tomosynthesis (DBT). It hard to be detected due its subtle appearance and similar intensity with surrounding tissue. To assist radiologists detect ADs, a single-view based computer-aided detection model DBT was developed by us previously. In this study, considering fact that always use information from craniocaudal (CC) mediolateral oblique (MLO) views simultaneously for better diagnosis each clinic, we...
Zanthoxylum myriacanthum Wall. ex Hook. f., a plant belonging to the Rutaceae family and genus, is extensively utilized for its medicinal properties as culinary seasoning in China Southeast Asian countries. However, chemical composition biological activities of Z. branches leaves remain insufficiently explored. In this study, volatile non-volatile components were analyzed using GC-MS UPLC-Q-Orbitrap HRMS techniques. A total 78 compounds 66 identified. The predominantly terpenoids aliphatic...
With the development of liquid biopsy technology, demand for noninvasive prenatal testing (NIPT) is increasing rapidly. The aim study to evaluate effects different blood collection tubes on plasma cfDNA and NIPT quality control.We investigated hemolysis, concentration, fragment distribution within samples stored in EDTA, ImproGene, Streck tubes. ImproGene control were evaluated.The prevented time-dependent increase concentration preserved size distribution. For control, there no significant...
As the coronavirus disease 2019 (COVID-19) epidemic spreads around world, demand for imaging examinations increases accordingly. The value of conventional chest radiography (CCR) remains unclear. In this study, we aimed to investigate diagnostic CCR in detection COVID-19 through a comparative analysis and CT. This study included 49 patients with 52 CT images radiographs pathogen-confirmed cases COVID-19-suspected that were found be negative (non-COVID-19). performance detecting was compared...
Objective: To evaluate the mammographic features, clinicopathological characteristics, treatments, and prognosis of pure mixed tubular carcinomas breast. Materials methods: Twenty-five were pathologically confirmed at our hospital from January 2011 to May 2019. Twenty-one patients underwent preoperative mammography. A retrospective analysis treatment, outcomes was performed. Results: Altogether, 95% (PTCs) (MTCs) showed presence a mass or structural distortions on mammography difference not...
Architectural distortion (AD) is one of the breast abnormal signs in digital tomosynthesis (DBT) and mammography (DM). It hard to be detected because its subtle appearance similar intensity with surrounding tissue. Since DBT a three-dimensional imaging, it can address problem tissue superimposition DM, so as reduce false positives negatives. Several clinical studies have confirmed that radiologists detect more ADs than DM. These conclusions are based on subjective experience. To explore...
Objective To assess the diagnostic performance of contrast-enhanced spectral mammography (CESM) in suspected breast lesions. Methods A total 97 patients with cancer identified by clinical examination or screening underwent two-views CESM on basis digital tomosynthesis (DBT) combined full-field (FFDM), and they were finally confirmed biopsy pathology. Three senior radiologists analyzed images, including lesion visibility, characteristics, enhancement type, degree enhancement, BIRDS...
Abstract Background: Computer-aided diagnosis (CAD) system can provide reference to radiologists in breast mass classification. This study was verify if a CAD model, based on perceptive features learned from quantitative BI-RADS descriptions, help improve performance for masses mammography. Methods: A retrospective multi-reader multi-case (MRMC) conducted evaluate model established features. Digital mammograms of 416 patients with were collected 2014 2017, including 231 benign and 185...