A5000560885- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Radiation Dose and Imaging
- Radioactivity and Radon Measurements
- Air Quality Monitoring and Forecasting
- Energy and Environment Impacts
- Noise Effects and Management
- Epigenetics and DNA Methylation
- Health, Environment, Cognitive Aging
- Urban Transport and Accessibility
- Energy, Environment, and Transportation Policies
- Radioactive contamination and transfer
- Vehicle emissions and performance
- Cardiovascular Health and Disease Prevention
- Human Health and Disease
- COVID-19 impact on air quality
- Heavy Metal Exposure and Toxicity
- Global Health Care Issues
Harvard University
2019-2024
Boston University
2023-2024
Harvard University Press
2023
Environmental Health
2022
Utrecht University
2021-2022
Abstract Objective To estimate exposure-response associations between chronic exposure to fine particulate matter (PM 2.5 ) and risks of the first hospital admission for major cardiovascular disease (CVD) subtypes. Design Population based cohort study. Setting Contiguous US. Participants 59 761 494 Medicare fee-for-service beneficiaries aged ≥65 years during 2000-16. Calibrated PM predictions were linked each participant’s residential zip code as proxy measurements. Main outcome measures...
Background: Exposure measurement error is a central concern in air pollution epidemiology. Given that studies have been using ambient predictions as proxy exposure measures, the potential impact of on health effect estimates needs to be comprehensively assessed. Objectives: We aimed generate wide-ranging scenarios assess direction and magnitude bias caused by errors under plausible concentration–response relationships between annual fine particulate matter [PM ≤2.5μm aerodynamic diameter...
Rationale: Risk of asthma hospitalization and its disparities associated with air pollutant exposures are less clear within socioeconomically disadvantaged populations, particularly at low degrees exposure. Objectives: To assess effects short-term to fine particulate matter (particulate an aerodynamic diameter ⩽2.5 μm [PM2.5]), warm-season ozone (O3), nitrogen dioxide (NO2) on risk among national Medicaid beneficiaries, the most population in United States, test whether any subpopulations...
Inhaling radon and its progeny is associated with adverse health outcomes. However, previous studies of the effects residential exposure to in United States were commonly based on a county-level temporally invariant model that was developed using measurements collected mid- late 1980s. We machine learning predict monthly concentrations for each ZIP Code Tabulation Area (ZCTA) Greater Boston area 363,783 short-term by Spruce Environmental Technologies, Inc., during period 2005–2018. A...
Individuals are exposed to air pollution and ionizing radiation from natural sources through inhalation of particles. This study investigates the association between cardiac arrhythmias short-term exposures fine particulate matter (particulate ≤2.5 µm aerodynamic diameter; PM2.5) particle radioactivity.Ventricular arrhythmic events were identified among 176 patients with dual-chamber implanted cardioverter-defibrillators in Boston, Massachusetts September 2006 June 2010. Patients assigned...
Temporally resolved assessment of residential exposure to radon is essential for investigating radon's acute health effects. Recent studies have used large numbers short-term measurements model the spatiotemporal variations in concentrations. However, most northeastern and midwestern United States were conducted basements, which less frequently occupied had higher average concentrations than upstairs spaces. Disproportionate usage basement potentially introduces misclassifications. In an...
Air pollution has been associated with carotid intima-media thickness test (CIMT), a marker of subclinical atherosclerosis. To our knowledge, this is the first study to report an association between ambient air and CIMT in younger adolescent population. investigate associations beyond standard mean regression by using quantile explore if occur at different percentiles distribution. We measured cross-sectionally age 16 years 363 adolescents participating Dutch PIAMA birth cohort. fit separate...
Particulate radioactivity, a characteristic of particulate matter, is primarily determined by the abundance radionuclides that are bound to airborne particulates. Exposure high levels radioactivity has been associated with negative health outcomes. However, there currently no spatially and temporally resolved data for exposure assessment purposes. We estimated monthly distributions gross beta across contiguous United States from 2001 2017 spatial resolution 32 km, via multi-stage...
Epigenome-wide association studies of ambient fine particulate matter (PM2.5) have been reported. However, few examined PM2.5 components (PMCs) and sources or included repeated measures. The lack high-resolution exposure measurements is the key limitation. We hypothesized that significant changes in DNA methylation might vary by PMCs sources.We predicted annual average 14 using novel models across contiguous U.S., between 2000-2018. resolution was 50 m × Greater Boston Area. also identified...
Cardiac arrhythmias have been associated with intense solar and geomagnetic activity (SGA) exposures to air pollution.We examined whether oscillations of SGA can modify the effect hourly pollutants on atrial fibrillation ≥30 s (AF) risk in patients dual-chamber implantable cardioverter-defibrillators. The effects ambient particulate matter <2.5 µm (PM2.5), black carbon (BC), ultrafine particles (PN), associations AF were assessed. Measures included wind proton density (SW), total...
Investigations into long-term fine particulate matter (PM 2.5 ) exposure's impact on nonaccidental and cardiovascular (CVD) deaths primarily involve nonrepresentative adult populations at concentrations above the new Environmental Protection Agency annual PM standard. Using generalized linear models, we studied exposure rates of five mortality outcomes (all nonaccidental, CVD, myocardial infarction, stroke, congestive heart failure) in 12 US states from 2000 to 2016. We aggregated predicted...
Our study adds to the sparse literature on effect of multiple fine particulate matter (PM2.5) components QT interval length, an outcome with high clinical relevance in vulnerable populations. To our knowledge, this is first examine association between spatiotemporally resolved exposures PM2.5 and length.
Cardiac arrhythmias have been associated with intense solar and geomagnetic activity (SGA) exposures to air pollution.We examined whether oscillations of SGA can modify the effect hourly pollutants on atrial fibrillation ≥30 seconds (AF) risk in patients dual chamber implantable cardioverter defibrillators (ICD). The effects ambient particulate matter <2.5 µm (PM2.5), black carbon (BC), ultrafine particles (PN), associations AF were assessed. Measures included wind proton density (SW), total...
BACKGROUND AND AIM: Exposure measurement error is a central concern in air pollution epidemiology. As studies have been using ambient predictions as proxy exposure measures, the potential impact of on health effect estimates needs to be comprehensively assessed. We aim generate wide-ranging scenarios assess direction and magnitude bias caused by errors under plausible concentration-response relationships between annual fine particulate matter (PM2.5) all-cause mortality. METHODS: use daily...
TPS 782: Health effects of emf, radiation and light, Johan Friso Foyer, Floor 1, August 28, 2019, 3:00 PM - 4:30 Background/Aim: Individuals are continuously exposed to DNA-damaging ionizing from terrestrial sources through inhalation. We examined the association between particle radioactivity cardiac arrhythmias. Methods: Ventricular arrhythmic events were identified among 176 patients with dual-chamber implanted cardioverter-defibrillators (ICDs) in Boston, Massachusetts September 2006...
Backgrounds and Aims: Our study adds to the sparse literature that examines whether arterial stiffness, related cardiovascular risk, increases with exposure air pollution. We assessed associations between spatio-temporally resolved pollutants vascular hemodynamics parameters in an elderly population based Eastern Massachusetts. Methods: Among 401 men living Massachusetts 2007 2019, we utilized time-varying linear mixed-effects regressions examine central augmentation index (%) pulse pressure...
Backgrounds and Aims: While many studies have found adverse health effects to ambient air pollution exposure, the combined of particulate matter (PM) components on measures arterial stiffness (central augmentation index central pulse pressure) not been evaluated. We aimed model pressure individual joint associations long-term exposure PM using a Bayesian Kernel machine regression (BKMR) approach compare results those from linear mixed-effects regressions. Methods: Central Augmentation (%)...
Background and Aim: Episodes of ventricular arrhythmias (VA) have been associated with environmental exposures such as air pollution. Solar driven geomagnetic disturbances may alter autonomic nervous system activity, modify systemic oxidative stress, or induce changes in aerosols. However, few studies investigated if there is an association between VA (GMD). The aim this study was to assess whether GMD the initiation patients implantable cardioverter defibrillators (ICDs). Methods: This...