Weiyu Hao

ORCID: 0000-0002-2203-0986
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About
Contact & Profiles
Research Areas
  • Insect and Pesticide Research
  • Environmental Toxicology and Ecotoxicology
  • Pharmacogenetics and Drug Metabolism
  • Pesticide and Herbicide Environmental Studies
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Pesticide Exposure and Toxicity
  • Analytical Chemistry and Chromatography
  • Drug Transport and Resistance Mechanisms
  • Microplastics and Plastic Pollution
  • Computational Drug Discovery Methods
  • Malaria Research and Control
  • Pesticide Residue Analysis and Safety
  • Pharmacological Effects and Assays
  • Physiological and biochemical adaptations
  • Carcinogens and Genotoxicity Assessment
  • Metabolomics and Mass Spectrometry Studies
  • Metabolism and Genetic Disorders
  • Glutathione Transferases and Polymorphisms
  • Animal Behavior and Reproduction
  • thermodynamics and calorimetric analyses
  • Mycotoxins in Agriculture and Food
  • Hydrogen's biological and therapeutic effects
  • Antibiotics Pharmacokinetics and Efficacy
  • Primate Behavior and Ecology
  • Speech and dialogue systems

Research Center for Eco-Environmental Sciences
2016-2024

Chinese Academy of Sciences
2016-2024

Henan Agricultural University
2024

University of Chinese Academy of Sciences
2016-2022

Affiliated Hospital of Qingdao University
2013

Qingdao University
2013

Myclobutanil (MT), a chiral fungicide, can be metabolized enantioselectively in organisms. In this work, the associated absorption, distribution, metabolism and transcriptional responses of MT rats were determined following single-dose (10 mg·kg–1 body weight) exposure to rac-, (+)- or (−)-MT. The enantiomer fractions (EFs) less than 0.5 with time liver, kidney, heart, lung, testis, suggesting preferential enrichment (−)-MT these tissues. Furthermore, there was conversion (+)-form (−)-form...

10.1021/acs.est.8b01721 article EN Environmental Science & Technology 2018-06-29

As a phenylpyrazole insecticide, flufiprole is an important substitute for fipronil in the agricultural field of China. However, its bioaccumulation and metabolism terrestrial organisms especially lizards living area have rarely been investigated. ectothermic animal, are also sensitive to temperature changes. Considering global warming, this study measured bioaccumulation, metabolism, hepatotoxicity Chinese native lizard (Eremias argus) under different stresses. Lizards exposed...

10.1021/acs.est.3c01049 article EN Environmental Science & Technology 2023-07-25

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10.2139/ssrn.4772331 preprint EN 2024-01-01

Mycotoxin cocontamination is a severe threat to health and economic security worldwide. The mycotoxins aflatoxin B1 (AFB1), zearalenone (ZEN), deoxynivalenol, T-2 toxin, fumonisin B1, ochratoxin A are of particular concern due their substantial toxicity. Lac-W laccase with the unique property degrading these six in absence redox mediators. Nevertheless, degradation rates low. This work aims improve ability degrade elucidate its detoxification mechanism. Including mediators increased...

10.3390/toxins16110477 article EN cc-by Toxins 2024-11-04
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