A5059311571- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Proteoglycans and glycosaminoglycans research
- Analytical Chemistry and Sensors
- Advanced biosensing and bioanalysis techniques
- Porphyrin and Phthalocyanine Chemistry
- Supramolecular Chemistry and Complexes
- Dendrimers and Hyperbranched Polymers
- Metal-Organic Frameworks: Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Lipid Membrane Structure and Behavior
- Acoustic Wave Resonator Technologies
- Glycosylation and Glycoproteins Research
- Metal complexes synthesis and properties
- Magnetism in coordination complexes
- Carbohydrate Chemistry and Synthesis
- Sulfur Compounds in Biology
- Electrochemical Analysis and Applications
- Advanced Chemical Sensor Technologies
- Electrochemical sensors and biosensors
- Crystallography and molecular interactions
- Advanced Computing and Algorithms
- Advanced Nanomaterials in Catalysis
Nanjing Agricultural University
2017-2025
Dalian University
2019-2021
Dalian University of Technology
2019-2021
East China University of Science and Technology
2010-2020
College of Medical Sciences
2017-2020
Nanjing University
2014-2018
Chimie Biologique pour le Vivant
2015-2017
Collaborative Innovation Center of Advanced Microstructures
2016-2017
Metal–organic framework (MOF) nanosheets are a class of two-dimensional (2D) porous and crystalline materials that hold promise for catalysis biodetection. Although 2D MOF have been utilized in vitro assays, ways engineering them into diagnostic tools live animals much less explored. In this work, series successfully engineered highly sensitive selective platform vivo monitoring heparin (Hep) activity. The iron-porphyrin derivative is selected as ligand to synthesize archetypical with...
The combination of pyrrole and hemiquinone units produced a novel prototype efficient colorimetric fluoride sensors, the presence tautomerism effect provides additional means modulating sensing behavior.
Di- and tripyrrin Zn<sup>2+</sup> sensors exhibit CHEF-type fluorescence enhancement by factors up to 72, with tunable emission colours.
2,2′-Dipyridylamine and anthracene units were linked to afford highly emissive compounds whose Cu2+ ensembles developed as effective fluorescence turn-on CN− probes.
For the rational design of fluorescence "turn-on" cyanide probes, a general strategy is developed by introducing dicyanovinyl group at sterically demanding position large π framework.
With the purpose of developing readily synthesized CHEF (chelation-enhanced fluorescence) type Zn(2+) probes with relatively simple molecular structures and excellent sensing behavior, p-anisoyl chloride was used for acylation 5-(pentafluorophenyl)dipyrromethane. Interestingly, α,β'-diacylated product PS2 a unique substitution mode obtained in high yield addition to normal α-substituted mono- diacylated products PS1 PS3. Further oxidation PS1-PS3 afforded dipyrrins S1-S3. Crystal structure...
Cyanide sensing has attracted increasing interest due to its toxicity and wide use in industrial activities. Herein, we developed three colorimetric cyanide sensors by the modification of α-position a dipyrrin chromophore with various carbonyl groups, namely, C6F5CO, C6H5CO CHO for 1, 2 3, respectively. In dichloromethane, these respond both CN− F− distinct colour changes. UV-Vis, 1H NMR HRMS measurements imply two-process interaction between CN−. Initially, forms hydrogen bond NH moiety,...
The conjugation of tetraphenylethene and a heparin binding peptide afforded “turn on” fluorescent probe for reliable determination its contaminant oversulfated chondroitin sulfate.
The detection of moisture in organic solvents is very important before their use water-sensitive reactions. Herein, we report that coumarins D1 and D2 were able to generate the corresponding copper complexes D1-Cu D2-Cu common solvents, which can be used as efficient fluorescent turn-on sensors for water. Single-crystal diffraction analysis reaction product indicated sensing mechanism based on formation a water-bridged 3D supramolecular hydrogen-bonding network. We demonstrated hydroxyl or...
Self-assembly of N,N,N′,N′-tetra(4-pyridyl)-1,4-phenylenediamine (L1) and N,N-di(2-pyridyl)-N′,N′-di(4-pyridyl)-1,4-phenylenediamine (L2) with MX2 (M = Zn, Cd, Hg; X Cl, Br, I) generated novel supramolecular structures a rich structural diversity. In the crystal L1, all pyridyl rings are involved in intermolecular π···π stacking T-shaped C−H···π interactions to form two-dimensional (2D) network. [CdL1Cl2]n·nH2O (4), [CdL1I2]n (6), [HgL1Cl2]n (7), [HgL1Br2]n (8), [Cd4(L2)4Cl8]n·2nDMF (13),...
Accurate discrimination of complicated glycosaminoglycans is a challenging but meaningful task for ensuring their safe use in clinics. With the purpose reducing production cost sensor arrays glycosaminoglycans, three fluorescence turn-on sensors named TPPEBA, TPPEMe, and TPPEC7 were readily synthesized by simple alkylation pyridyl units π-extended AIEgen, namely, tetra-(4-pyridylphenyl) ethylene. The designed are cross-reactive toward tested including heparin, chondroitin sulfate, hyaluronic...
The design and syntheses of novel ligands are essential for developing coordination compounds with structures interesting properties. In this work, we designed synthesized a ligand bis(4,4′-dipyridylaminophenylene)butadiyne (L) by attaching two 4,4′-dipyridylamine moieties to flexible butadiyne linker. Starting from ligand, seven polymers [Zn2L(HCOO)3(OH)]n (1), [Cd2L2Cl4]n·3nDMF·3nH2O (2), [CdLBr2]n (3), [Cd6L3(SO4)6]n·4nMeCN (4), [Hg2LBr4]n·3nCH2Cl2·nH2O (5), [Cu2LI2]n·0.5nCH2Cl2 (6),...
Functional nanomaterials have found wide applications in diverse areas because of their intrinsically different properties compared to bulk counterparts. To achieve the goal preparing functional nanomaterials, various strategies been successfully developed. Among them, biomolecule-directed approach has extensively explored synthesize many owing programmability, self-assembly and recognition capabilities. This Feature Article highlights use lysozyme as a model protein direct synthesis...
Directly linked porphyrin dimers have attracted considerable attention because of their intriguing electronic features. Most emphasis has been placed on either with large dihedral angles between the constituent planar monomeric subunits or those overall planarity, referred to as "Planar-Twisted-Planar" and "Planar-Planar-Planar", respectively. Herein, we report a "Twisted-Planar-Twisted" framework, hexaphyrin dimer D that exists in trans configuration. Treatment MeOH affords two isomeric...
Heparin (Hep), widely used in clinics as an anticoagulant drug, has high degrees of heterogeneity and shares a similar disaccharide repeating unit with its GAG analogues. The development reliable convenient methods to discriminate Hep from analogues detect trace contaminants is meaningful for safe usage clinics. Herein, five porphyrin-GO nanocomposites denoted PP1-GO, PP2a-GO, PP2b-GO, PP3-GO, PP4-GO were synthesized by assembling corresponding positively charged porphyrins onto the surface...
By combining leucine (Leu) and tetraphenylethene (TPE), a pH-sensitive aggregation induced emission (AIE) probe <bold>TPE-Leu</bold> was developed.
Most reported Zn2+ probes suffer from the interference of background fluorescence originated conjugated structures commonly utilized fluorophores. In this work, three novel meso-hydroxyl group substituted dipyrromethanes DPMOH1–DPMOH3 were synthesized and found to be colourless nonfluorescent due interruption π system by an sp3 carbon between two pyrrolic units. Interestingly, only addition solutions promoted their oxidation dipyrrin forms, bright "turn on" was observed formation...
An unusual arylboronate based fluorescent probe<bold>R1</bold>was synthesized for the selective and sensitive detection of ClO<sup>−</sup>.