A5016251352- Advanced Nanomaterials in Catalysis
- Nanocluster Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Electrochemical sensors and biosensors
- Catalysis and Oxidation Reactions
- Marine Biology and Environmental Chemistry
- Catalytic Processes in Materials Science
- Microplastics and Plastic Pollution
- Polymer Surface Interaction Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Cellulose Research Studies
- Metal-Organic Frameworks: Synthesis and Applications
- Mesoporous Materials and Catalysis
- Graphene and Nanomaterials Applications
- Surfactants and Colloidal Systems
- Agriculture, Soil, Plant Science
- Fluid Dynamics and Mixing
- Nanomaterials for catalytic reactions
- Oral microbiology and periodontitis research
- Quantum Dots Synthesis And Properties
- Innovative Microfluidic and Catalytic Techniques Innovation
- Nanoparticles: synthesis and applications
- Electrocatalysts for Energy Conversion
- Environmental remediation with nanomaterials
Tianjin University
2010-2025
State Ethnic Affairs Commission
2025
Ministry of Natural Resources
2025
Tianjin University of Science and Technology
2023-2024
Ministry of Natural Resources
2023-2024
Nanjing University
2003-2022
Collaborative Innovation Center of Advanced Microstructures
2016-2021
University of Illinois Urbana-Champaign
2013-2014
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2014
Kansas State University
1990
Gold nanoparticles (AuNPs) with simultaneous plasmonic and biocatalytic properties provide a promising approach to developing versatile bioassays. However, the combination of AuNPs' intrinsic enzyme-mimicking their surface-enhanced Raman scattering (SERS) activities has yet be explored. Here we designed peroxidase-mimicking nanozyme by in situ growing AuNPs into highly porous thermally stable metal–organic framework called MIL-101. The obtained AuNPs@MIL-101 nanozymes acted as peroxidase...
Reactive oxygen species (ROS)-induced oxidative stress is linked to various diseases, including cardiovascular disease and cancer. Though highly efficient natural ROS scavenging enzymes have been evolved, they are sensitive environmental conditions hard mass-produce. Therefore, enormous efforts devoted developing artificial with activities. Among them, nanozymes recently attracted great interest owing their enhanced stability, multi-functionality, tunable activity. It has implicated that...
Metal–organic framework (MOF) nanosheets are a class of two-dimensional (2D) porous and crystalline materials that hold promise for catalysis biodetection. Although 2D MOF have been utilized in vitro assays, ways engineering them into diagnostic tools live animals much less explored. In this work, series successfully engineered highly sensitive selective platform vivo monitoring heparin (Hep) activity. The iron-porphyrin derivative is selected as ligand to synthesize archetypical with...
Pesticides, widely used for pest control and plant growth regulation, have posed a threat to the environment human health. Conventional methods analyze pesticide residues are not applied resource-limited areas because of their high cost, complexity, requirements expensive instruments (such as GC/MS LC/MS). To address these challenges, herein we fabricated colorimetric nanozyme sensor arrays based on heteroatom-doped graphene detection aromatic pesticides. The active sites nanozymes could be...
Glutathione peroxidase (GPx) plays an important role in maintaining the reactive oxygen metabolic balance, yet limited GPx-mimicking nanozymes are currently available for vivo therapy. Herein, a ligand engineering strategy is developed to modulate activity of metal-organic framework (MOF) nanozyme. With different substituted ligands, activities MIL-47(V)-X (MIL stands Materials Institute Lavoisier; X=F, Br, NH2 , CH3 OH, and H) MOFs rationally regulated. best one as example, both vitro...
Abstract The activity of nanomaterials (NMs) in catalytically scavenging superoxide anions mimics that dismutase (SOD). Although dozens NMs have been demonstrated to possess such activity, the underlying principles are unclear, hindering discovery as novel SOD mimics. In this work, we use density functional theory calculations study thermodynamics and kinetics catalytic processes, develop two principles, namely, an energy level principle adsorption principle, for activity. first...
Periodontitis, an inflammatory disease of oxidative stress, occurs due to excess reactive oxygen species (ROS) contributing cell and tissue damage which in turn leads alveolar bone resorption as well the destruction other periodontal support tissues. With significant recent advances nanomaterials, we considered a unique type nanomaterials possessing enzyme-like characteristics (called nanozymes) for potential future clinical applications, especially light increasing number studies evaluating...
Attributed to nanoscale proximity effects, integrated nanozymes with superior activities, specificity, and stability will be a hot topic in the future.
Abstract While the unique physicochemical properties of nanomaterials that enable regulation nanozyme activities are demonstrated in many systems, quantitative relationships between structure and their enzymatic remain poorly understood, due to heterogeneity compositions active sites these nanomaterials. Here, inspired by metalloenzymes with well‐defined metal–ligand coordination, a set substituted metal–organic frameworks (MOFs) similar coordination is employed investigate relationship...
One of the current challenges in nanozyme-based nanotechnology is utilization multifunctionalities one material. In this regard, Au@Pt nanoparticles (NPs) with excellent enzyme-mimicking activities due to Pt shell and unique surface plasmon resonance features from Au core have attracted enormous research interest. However, not been widely utilized. The practical problem optical-damping nature hinders into combination NPs' properties their surface-enhanced Raman scattering (SERS) activities....
Combining the intrinsic enzyme-mimicking properties of nanomaterials with their unique characteristics enables design multifunctional nanozymes for new biomedical applications and beyond.
Panax notoginseng is a prominent traditional Chinese medicinal herb, yet its yield and quality are significantly constrained by continuous cropping obstacles, primarily stemming from soil-related issues. This study analyzed soils subjected to various degrees of P. cultivation, without planting, natural forest floor soil planting. The objective was investigate variations in microbial communities, physicochemical properties, enzyme activities across different conditions. Macro-genome...
A systematic investigation of the effects different DNA sequences on morphologies silver nanoparticles (AgNPs) grown from Ag nanocube seeds is reported. The presence 10-mer oligo-A, -T, and -C directed AgNPs growth cubic into edge-truncated octahedra truncation extents truncated tetrahedral AgNPs, while in oligo-G remained cubic. shape morphological evolution nanoparticle for each system investigated using SEM TEM correlated with UV–vis absorption kinetic studies. In addition, roles oligo-C...
Facile-regulation of the multi-enzyme-mimicking activities and effective guidelines from radar analysis established here advance further biomedical applications ceria-based nanozymes.
The use of oxidoreductase nanozymes to regulate reactive oxygen species (ROS) has gradually emerged in periodontology treatments. However, current for treating periodontitis eliminate ROS extensively and non-specifically, ignoring the physiological functions under normal conditions, which may result uncontrolled side effects. Herein, using MIL-47(V)-F (MVF) nanozyme, mimics function glutathione peroxidase (GPx), it is proposed that can be properly regulated by specifically eliminating H
Functional nanomaterials with enzyme-mimicking activities, termed as nanozymes, have found wide applications in various fields. However, the deviation between working and optimal pHs of nanozymes has been limiting their practical applications. Here we develop a strategy to modulate microenvironmental metal-organic framework (MOF) by confining polyacids or polybases (serving Brønsted acids bases). The confinement poly(acrylic acid) (PAA) into channels peroxidase-mimicking PCN-222-Fe (PCN =...
The aggregation behaviors of silver atoms modulated by polymorphic DNA templates involving i-motif, G-quadruplex, and the Watson-Crick duplex, were investigated using density functional theory (DFT) calculations, combining with experimental characterizations CD, UV, fluorescence measurements TEM, in order to understand reason molecular level that affect emitting species Ag nanomaterials. First, affinity sites ions on different analyzed DFT conformational variations caused disclosed. Second,...