Lijun Han

ORCID: 0000-0002-6415-5656
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About
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Research Areas
  • Pesticide Residue Analysis and Safety
  • Analytical chemistry methods development
  • Pesticide and Herbicide Environmental Studies
  • Insect and Pesticide Research
  • Pharmacological Effects and Assays
  • Analytical Chemistry and Chromatography
  • Antibiotics Pharmacokinetics and Efficacy
  • Fungal Plant Pathogen Control
  • Weed Control and Herbicide Applications
  • Microbial Applications in Construction Materials
  • Synthesis and Biological Evaluation
  • Chromium effects and bioremediation
  • Agricultural safety and regulations
  • Mine drainage and remediation techniques
  • Synthesis and biological activity
  • Pesticide Exposure and Toxicity
  • Advanced Chemical Sensor Technologies
  • Electrochemical sensors and biosensors
  • Analytical Methods in Pharmaceuticals
  • Fungal Biology and Applications
  • Adsorption and biosorption for pollutant removal
  • Insect-Plant Interactions and Control
  • Mycotoxins in Agriculture and Food
  • Environmental Toxicology and Ecotoxicology
  • Environmental remediation with nanomaterials

China Agricultural University
2016-2025

Yancheng Institute of Technology
2025

Wuhan University of Technology
2025

Institute of Rock and Soil Mechanics
2020-2024

Nanyang Technological University
2023

University of Chinese Academy of Sciences
2020-2023

Weifang University
2022

Eastern Regional Research Center
2015-2020

Agricultural Research Service
2015-2020

Ocean University of China
2018

Pesticides, widely used for pest control and plant growth regulation, have posed a threat to the environment human health. Conventional methods analyze pesticide residues are not applied resource-limited areas because of their high cost, complexity, requirements expensive instruments (such as GC/MS LC/MS). To address these challenges, herein we fabricated colorimetric nanozyme sensor arrays based on heteroatom-doped graphene detection aromatic pesticides. The active sites nanozymes could be...

10.1021/acs.analchem.9b05110 article EN Analytical Chemistry 2020-05-04

In this study, a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) method was established for the extraction cleanup of fipronil its three metabolites (fipronil solfone, sulfide, desulfinyl) in peanut kernel, shell, straw, seedling, soil samples, liquid chromatography-tandem mass spectrometry (LC-MS/MS) used analysis. The average recoveries were 66-116% at level 0.001-0.1 mg/kg with RSD <19%, limit detection 0.3 ng/g all matrices. dissipation experiment results demonstrated...

10.1021/jf5054589 article EN Journal of Agricultural and Food Chemistry 2015-02-09

This study demonstrated the application of an automated high-throughput mini-cartridge solid-phase extraction (mini-SPE) cleanup for rapid low-pressure gas chromatography—tandem mass spectrometry (LPGC-MS/MS) analysis pesticides and environmental contaminants in QuEChERS extracts foods. Cleanup efficiencies breakthrough volumes using different mini-SPE sorbents were compared avocado, salmon, pork loin, kale as representative matrices. Optimum extract load volume was 300 µL 45 mg...

10.1007/s10337-016-3116-y article EN cc-by Chromatographia 2016-06-13

In this study, a multi-residue analytical method using quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction dispersive solid-phase (d-SPE) cleanup, followed by high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS), was investigated for rapid determination of 60 pesticide residues in whole crayfish meat. The final used 10 mL acetonitrile extraction, 3 g NaCl partitioning, 50 mg primary secondary amine d-SPE cleanup. validated at three spiking levels...

10.1021/acs.jafc.7b05339 article EN Journal of Agricultural and Food Chemistry 2018-01-24

Organophosphate esters (OPEs) are chemicals extensively used as plasticizers and flame retardants in commercial consumer products. In this study, we developed validated a method for the analysis of 13 common OPEs meat (chicken, pork, beef) fish (catfish salmon) to study their occurrence those foods United States. The was based on QuEChERS extraction with acetonitrile automated robotic cleanup extracts, followed by low pressure gas chromatography-tandem mass spectrometry (GC-MS/MS) 8...

10.1021/acs.jafc.9b01548 article EN Journal of Agricultural and Food Chemistry 2019-06-27

Pyruvate kinase (PK) has been considered as a promising fungicide target discovered in our previous studies. Natural compounds are important sources for discovery and development of new pesticides. To continue ongoing studies on the novel PK-targeted fungicides, series psoralen derivatives including 1,3,4-oxadiazole moiety were designed by computer-aided pesticide molecular design method, synthesized, evaluated their fungicidal activity. The bioassay results indicated that 11d, 11e, 11g,...

10.1021/acs.jafc.1c07911 article EN Journal of Agricultural and Food Chemistry 2022-03-10

To discover novel inhibitors of pyruvate kinase (PK) as fungicidal candidates, a series 2-thiazol-2-yl-1,3,4-oxadiazole derivatives were designed by prediction model with Rhizoctonia solani PK (RsPK) protein target and YZK-C22 ligand. Fungicidal screening indicated that 5b, 5g, 5h, 5j, 5l, 5p, 5q, 5s exhibited equal or higher activity compared to against Botrytis cinerea, Cercospora arachidicola, R. solani. our surprise, showed comparable flutriafol an EC50 0.21 μg/mL vs 0.20 μg/mL, but over...

10.1021/acs.jafc.4c08092 article EN Journal of Agricultural and Food Chemistry 2025-01-06

L-valine holds wide-ranging applications in medicine, food, feed, and various industrial sectors. Escherichia coli, a pivotal strain production, features concise fermentation period well-defined genetic background. This study focuses on mismatch repair genes (mutH, mutL, mutS, recG) associated with mutagenesis (dinB, rpoS, rpoD, recA), employing high-glucose adaptive culture conjunction metabolic modifications to systematically screen for superior phenotypes. approach enhances the...

10.1007/s00253-024-13334-9 article EN cc-by-nc-nd Applied Microbiology and Biotechnology 2025-01-21

Nitrites are added as a preservative to variety of cured meats, including bacon, kill bacteria, extend shelf life, and improve quality. During cooking, nitrites in the meat can be converted carcinogenic nitrosamines (NAs), formation which is mitigated by addition antioxidants. In past, U.S. Department Agriculture (USDA) Food Safety Inspection Service (FSIS) monitored NAs pan-fried but FSIS terminated monitoring 1990s due very low levels found. recently chose conduct risk assessment cooked...

10.1021/acs.jafc.5b04527 article EN Journal of Agricultural and Food Chemistry 2015-11-06

Agrochemicals are indispensable materials in agricultural production, used to control or prevent diseases, insects and weeds, play important roles ensuring both food security safety. Meanwhile, the negative impacts of modern synthetic pesticides on humans environment could not be neglected. Thus, registration, application monitoring should strictly checked ensure their commercial product quality safety human health as well environment. This review summarizes analytical chemistry involved...

10.1016/j.aac.2022.11.002 article EN cc-by-nc-nd Advanced Agrochem 2022-11-12
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