Abstract Background The efficacy of the erector spinae plane (ESP) block in mitigating postoperative pain has been shown for a range thoracic and abdominal procedures. However, there is paucity literature investigating its impact on analgesia as well influence weaning subsequent recovery comparison to epidural (TEA) median sternotomy-based approach open-cardiac surgeries hence study. Methods Irrespective gender or age, 74 adult patients scheduled undergo open cardiac surgery were enrolled...

The term "lean production," also known as "Lean," describes a process of operations management pioneered at the Toyota Motor Company that contributed significantly to success company. Although developed by Toyota, Lean has been implemented many other organizations, including those in health care, and should be considered dental schools evaluating their clinical operations. combines engineering principles with improvement tools optimize business operating processes. One core concepts is...

The aim was to assess the health-related quality of life (HRQOL) and its temporal variation at first visit subsequent visits among breast cancer patients.The prospective study carried out in Outpatient Department Radiation Oncology, University Teaching Tertiary Referral Hospital.After clearance from ethical committee EORTC group, 81 surgically treated female patients referred Oncology for chemoradiation hormonal therapy were included after informed written consent, irrespective age stage...

Aim: The aim of this study was to analyze the demographic features, reproductive history and stage at disease presentation among female breast cancer patients.Design Setting: present prospective hospital-based conducted in Department Radiation Oncology, University Teaching Tertiary Referral Hospital.Materials Methods: After approval from Institute's ethical committee, 132 patients surgically treated either by mastectomy or conserving surgery (BCS) then referred department radiation oncology...

The disease and surgery of the breast not only evoke a fear mutilation loss feminity but is also responsible for psychosocial, behavioral, sexual problems.To analyze prospectively time trends in "breast specific functional symptom scale scores female cancer survivors."The prospective study was conducted Department Radiation Oncology at Tertiary Referral Hospital.A total 154 operated (mastectomy) patients who were referred to chemoradiation ± target therapy (trastuzumab) hormonal (tamoxifen)...

Post thoracotomy ipsilateral shoulder pain (PTISP) is a distressing and highly prevalent problem after thoracic surgery has not received much attention despite the incidence as high 85%.To study effect of phrenic nerve infiltration with Ropivacaine compared to paracetamol infusion on PTISP in patients epidural analgesia standard mode incisional both groups.Prospective Randomised Double Blind Study.126 adult were divided randomly into 2 groups, "Group A (Phrenic Nerve Infiltration Group) 10...

Background: Laparoscopic cholecystectomy (LC) has revolutionized minimally invasive surgery, considered as gold standard and increasing number of procedures are done for patients with various high risk comorbid conditions.LC today can be straightforward operation, but may also an operative approach fraught underlying complexities necessitating conversion to open leading longer time, hospital stay more postoperative morbidity higher costs.We have tried estimate the rate factors which...

Primary sino-nasal neuroendocrine carcinomas (PSNNECs) are rare, with a wide spectrum of histological differentiation. Advanced tumors may invade the surrounding structures, such as skull base, orbit, or brain. Here, we present rare case PSNNEC and its management by concurrent chemoradiation (CCRT) followed adjuvant chemotherapy radiological resolution tumor mass.

Myasthenia gravis (MG), a rare disorder of the neuromuscular transmission, is increasingly acknowledged as syndrome rather than single disease.In recent past, there has been an active search for new antigens in myasthenia gravis, whereas clinical and experimental studies have provided insights into crucial pathways immune regulation, which might become targets future therapeutics.This review summarizes various genes involved pathophysiology MG, confirm disease heterogeneity may help find...

Abstract Context: Successful management of Wilm's tumor (WT) necessitates meticulous attention for proper staging and collaborative effort its optimal management. Aims: The aim the study was to observe patterns WT. Settings Design: This a single-institutional retrospective study. Subjects Methods: Twenty-three WT case records were analyzed over 6 years data collected interpreted as number, percent, mean ± standard deviation with regard clinicodemographic aspects, staging, diagnostic modality...

Preoperative patient education is an essential responsibility of any healthcare provider, especially anaesthetist, and beneficial for perioperative outcome. A smooth emergence extubation a clinical skill that needs to be mastered by anaesthetist. The aim this study was analyse whether detailed preoperative improves the quality preparedness at from general anaesthesia.One hundred patients were randomly assigned two groups. group received counselling about mode anaesthesia, process their...

Background In England, many people of South Asian origin consume smokeless tobacco (ST). ST use can lead to oral cancer, which is disproportionately high in Asians. Our aims were assess the compliance product retailers with statutory regulations and explore supply chain ST. Methods We undertook a multimethods study between August 2017 July 2019 five English boroughs proportion ethnic purchased products conducted field surveys at point sale. Qualitative interviews suppliers. packs assessed...

Introduction: Drug abuse is a global public health issue that poses significant challenges to healthcare systems particularly in intensive care units (ICU). This study aims assess the clinical profile and outcomes of drug patients admitted ICU tertiary hospital North India.Methods: A prospective observational was conducted over period 3 years involving ICU. Demographic data, characteristics, substance patterns, co-morbidities, severity scores were recorded.Results: total 35 included study....

A BSTRACT Artificial intelligence (AI) is revolutionizing health care by addressing some of the important concerns, health-care organizations face daily. All partners in system must understand AI technologies and how they might improve effectiveness accessibility AI-based services, leading to value-based care. Effective proper use primary emphasis this narrative review article, which also helps readers grasp basic ideas underlying AI. Despite fact that still its infancy other sectors care,...

A BSTRACT Background: Radiation-induced ovarian ablation (ROA) was one of the main modalities in early years inducing suppression hormone levels estradiol (E 2 ) and follicle-stimulating hormones (FSHs) estrogen receptor/progesterone receptor-positive breast cancer patients. However, as newer techniques such medical (MOS) laparoscopic oophorectomies (LOs) emerged, ROA began to take a back seat. Nonetheless, remains valuable option for certain patients with specific indications. It is worth...

Neurosurgical procedures are associated with profound blood loss that necessitates need for intraoperative and postoperative transfusion. Excessive ordering of based on physicians' habitual practice may lead to unintentional misuse bank services. For the optimal use resources, transfusion practices have be appropriate.The aim this study is cross match ratio review utilization (transfusion index maximal surgical order schedule) in elective neurosurgical procedures.A prospective, observational...

Plerixafor reversibly inhibits binding of stromal cell-derived factor 1 alpha to the chemokine receptor CXCR4 resulting in mobilization bone marrow hematopoietic progenitor cells. Phase III studies demonstrate that plerixafor given on day 4 G-CSF treatment significantly improves chances successful peripheral blood stem cell collection compared alone patients with multiple myeloma (MM) and non-Hodgkin lymphoma (NHL). In context an IRB approved phase II clinical trial, we studied whether could...

Status asthmaticus is an acute exacerbation of asthma that remains unresponsive to initial treatment with bronchodilators.Status can vary from a mild form severe bronchospasm, airway inflammation, and mucus plugging cause difficulty in breathing, carbon dioxide retention, hypoxemia, respiratory failure.Typically, patients present few days after the onset viral illness, following exposure potent allergen or irritant, exercise cold environment.Lidocaine local anaesthetic blocks voltage gated...

Renal cell carcinoma (RCC) has widespread and unpredictable metastatic potential, even when the curative nephrectomy is performed. RCC can metastasize via venous lymphatic routes virtually to any site but commonly metastasizes lungs, lymph nodes, bones, liver, brain. Muscular metastases are rare from RCC. After 22 years of radical disease-free follow-up, patient presented with discomfort on walking climbing upstairs also complained thigh swelling confirmed clinical examination. Noncontrast...