- Optimization and Variational Analysis
- CAR-T cell therapy research
- Fuzzy Systems and Optimization
- Energy and Environment Impacts
- Protein Degradation and Inhibitors
- Probabilistic and Robust Engineering Design
- Anesthesia and Pain Management
- Nausea and vomiting management
- Smart Grid Energy Management
- Monoclonal and Polyclonal Antibodies Research
- Artificial Intelligence and Decision Support Systems
- South Asian Studies and Conflicts
- vaccines and immunoinformatics approaches
- E-Government and Public Services
- Biosimilars and Bioanalytical Methods
- Acute Lymphoblastic Leukemia research
- Analytic and geometric function theory
- Contact Mechanics and Variational Inequalities
- Anesthesia and Sedative Agents
- Topology Optimization in Engineering
- Library Science and Information Literacy
- Global Energy and Sustainability Research
- Nonlinear Differential Equations Analysis
- Agricultural risk and resilience
- Nuts composition and effects
Aligarh Muslim University
2025
Otto-von-Guericke University Magdeburg
2023-2024
Sher-i-Kashmir Institute of Medical Sciences
2014-2024
Devi Ahilya Vishwavidyalaya
2017
National Institute of Technology Srinagar
2008-2009
Abstract Background The efficacy of the erector spinae plane (ESP) block in mitigating postoperative pain has been shown for a range thoracic and abdominal procedures. However, there is paucity literature investigating its impact on analgesia as well influence weaning subsequent recovery comparison to epidural (TEA) median sternotomy-based approach open-cardiac surgeries hence study. Methods Irrespective gender or age, 74 adult patients scheduled undergo open cardiac surgery were enrolled...
The growing dependence on optimization models in decision-making has created a demand for tools that can facilitate the formulation and resolution of broader range real-world processes systems associated with human activity. These situations often involve assumptions diverge from traditional methodologies. One viable approach addressing problems real-life scenarios uncertainty is interval-valued optimization. Taking into account significance optimization, this paper, we derive first second...
Abstract CD19‐directed immunotherapy has become a cornerstone in the therapy of B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL). cellular and antibody‐based therapeutics have entered primary relapsed disease contributed to improved outcomes lower toxicity. However, efficacy remains limited many cases due lack response, short remission phases, or antigen escape. Here, BCP‐ALL cell lines, patient‐derived xenograft (PDX) samples, human macrophages, an vivo transplantation model...
Children with acute lymphoblastic leukemia (ALL) have a favorable prognosis; however, diagnosis and treatment of central nervous system (CNS)-involvement remain challenging, particularly in T-cell ALL (T-ALL).1 Due to insufficient strategies conclusively diagnose treat CNS-disease, all patients receive risk-adapted potent CNS-directed chemotherapies, which can cause severe toxicity is associated neurocognitive deficits.1,2 Recent research has identified distinguishing features CNS-ALL cells...
As the number of patients having implantable cardioverter defibrillator (ICD) devices is increasing, it important for physicians and to be aware situations conditions that can result in interference with normal functioning these devices. There are multiple cases malfunction ICDs reported literature may great significance have an overview incidents appropriate recognition future prevention. Here we reviewing available as well reporting interesting case electromagnetic (EMI) resulting from...
SYNOPSIS This study presents the analysis and results of a pilot survey regarding energy consumption patterns for major end-uses in residential sector Kashmir valley Indian province Jammu Kashmir. The consuming are space heating, water cooking lighting. A questionnaire was designed to collect responses. total 120 households were interviewed their purchase patterns, source usage different end-uses, types sources systems rural urban reasons choice. covered income group families areas. Space...
Background: Intrathecal α2 agonists prolong the duration of action local anesthetics and reduce required dose.Dexmedetomidine is a receptor agonist its α2/α1 selectivity 8 times higher than that clonidine.Aims: In this study, we aimed to investigate effect adding dexmedetomidine intrathecal bupivacaine on onset time motor sensory blocks.Methods: Patients were randomly assigned into two groups.Group B(n= 30) patients received 3ml (15mg) 0.5% +0.5ml normal saline Group BD (n= (15 mg) + 0.5ml...
SYNOPSIS An attempt to assess the financial feasibility of space heating systems used in Kashmir valley has been made. The include Electric heater, LPG radiant Bukhari (the metallic heater) and Kangri portable heater). A typical household comprising six members considered for comparison various options. figures merit analysis are total annual cost per hour heating. sensitivity studied numbers days operation, different hours daily operation rate fuel price escalation. impact on with percent...
The genus Betula, commonly known as birch, belongs family Betulaceae. There are approximately 50 recognized species of all which essential ecological components northern temperate and boreal forests in many parts the world. extensive stands this have originated on southern slopes ravines East Asia (Afghanistan, Pakistan, India) South China. prefers moist sandy loam soil can tolerate strong winds high freezing temperatures but not maritime exposure. Betula's forms tree line vegetation at...
In this paper, we present strongly geodesic preinvexity on Riemannian manifolds (RM) and {\eta}-invexity of order m RM. Furthermore, define invariant {\eta}-monotonicity Under Condition C, an important characterization these functions are studied. We construct several non-trivial examples in support definitions. Afterwords, significant a strict {\eta}-minimizers ({\eta}-minimizers)of for MOP solution to the variational like-inequality problem (VVLIP) has been derived.
<p>A file containing supplementary figures 1-8 and the table S1.</p>
<p>A file containing RPPA and RNAseq datasets, pathway analyses prediction calculations presented in the main figures.</p>
<p>A file containing RPPA and RNAseq datasets, pathway analyses prediction calculations presented in the main figures.</p>
<p>A file containing supplementary figures 1-8 and the table S1.</p>
This paper introduces the concepts of strongly geodesic preinvexity, η -invexity order m , and invariant -monotonicity on Riemannian manifolds. Additionally, it discusses an important characterization these functions under a condition, known as Condition C (The is defined in Remark 1 this article), by Barani Pouryayevali [ J. Math. Anal. Appl. 328 (2007) 767–779]. The provides various non-trivial examples to support definitions. Furthermore, presents significant strict -minimizers (or...
This article explores fundamental properties of convex interval-valued functions defined on Riemannian manifolds. The study employs generalized Hukuhara directional differentiability to derive KKT-type optimality conditions for an optimization problem Based type involved in problems, we consider the following cases: 1. objective function as well constraints are real-valued; 2. is and 3. contraints interval-valued. whole theory justified with help examples. order relation that use throughout...
The KKT optimality conditions for multi-objective interval-valued optimization problem on Hadamard manifold are studied in this paper. Several concepts of Pareto optimal solutions, considered under LU and CW ordering the class all closed intervals $\mathbb{R}$, given. presented notions convexity, pseudo-convexity generalized Hukuhara difference. We show, with help an example, that results done paper solving problems spaces more general than existing ones Euclidean spaces. main supported by examples.
<div>Abstract<p>Despite impressive advances in melanoma-directed immunotherapies, resistance is common and many patients still succumb to metastatic disease. In this context, harnessing natural killer (NK) cells, which have thus far been sidelined the development of melanoma immunotherapy, could provide therapeutic benefits for cancer treatment. To identify molecular determinants NK cell–mediated killing (<i>NKmK</i>), we quantified NK-cell cytotoxicity against a...
The ‘E’ in E-Governance stands for ‘Electronic’. Thus, is basically associated with carrying out the functions and achieving results of governance through utilization what has today come to be known as Information Communication Technology (ICT). new technologies offer vast opportunities progress all walks life. Since Internet evolved rapidly last few years, there a need think strategically about where we want future. technology well initiatives have long way since then. refers...